Memory switched B cell percentage and not serum immunoglobulin concentration is associated with clinical complications in children and adults with specific antibody deficiency and common variable immunodeficiency

Clinical Immunology

Volumn 120, Issue 3, 2006, Pages 310-318

  Alachkar, Hana ^a   Taubenheim, Nadine ^b   Haeney, Mansel R ^a   Durandy, Anne ^b   Arkwright, Peter D ^c  

^a HOPE HOSPITAL   (United Kingdom)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

B cell switching; Bronchiectasis; CVID; Specific antibody immunodeficiency; Splenomegaly

Indexed keywords

ANTIBIOTIC AGENT; BIOCHEMICAL MARKER; CD19 ANTIGEN; CD27 ANTIGEN; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN D; PNEUMOCOCCUS VACCINE;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; BACTERIAL INFECTION; BRONCHIECTASIS; CELL COUNT; CELLULAR IMMUNITY; CHILD; COMMON VARIABLE IMMUNODEFICIENCY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE CLASSIFICATION; EAR INFECTION; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNE DEFICIENCY; HUMORAL IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; INFLUENZA; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MEMORY CELL; PREVALENCE; PRIORITY JOURNAL; SPLENOMEGALY; STREPTOCOCCUS INFECTION; UNITED KINGDOM;

ADOLESCENT; ADULT; AGED; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; BRONCHIECTASIS; CHILD; CHILD, PRESCHOOL; COMMON VARIABLE IMMUNODEFICIENCY; FEMALE; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULINS; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MUTATION; PREDICTIVE VALUE OF TESTS; SPLENOMEGALY;

EID: 33746786376     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2006.05.003     Document Type: Article

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