Roles of bone marrow, mucosa and lymphoid tissues in pathogenesis of murine IgA nephropathy

Contributions to Nephrology

Volumn 157, Issue , 2007, Pages 164-168

  Aizawa, Masashi ^a   Suzuki, Yusuke ^a   Suzuki, Hitoshi ^a   Pang, Huihua ^a   Kihara, Masao ^a   Yamaji, Kenji ^a   Horikoshi, Satoshi ^a   Tomino, Yasuhiko ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A;

ADOPTIVE TRANSFER; ANIMAL; BLOOD; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CONFERENCE PAPER; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOLOGY; LYMPHOID TISSUE; MOUSE; MUCOSA; PATHOLOGY; PLASMA CELL;

ADOPTIVE TRANSFER; ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; GLOMERULONEPHRITIS, IGA; IMMUNOGLOBULIN A; LYMPHOID TISSUE; MICE; MUCOUS MEMBRANE; PLASMA CELLS;

EID: 34249015583     PISSN: 03025144     EISSN: None     Source Type: Book Series    
DOI: 10.1159/0000102462     Document Type: Conference Paper

References (8)

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3. Harper SJ, Allen AC, Feehally J, et al: Increased dimeric IgA producing B cells in the bone marrow in IgA nephropathy determined by in situ hybridisation for J chain mRNA. J Clin Pathol 1996;49:38-42.
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5. Suzuki H, Suzuki Y, Tomino Y, et al: Genome-wide scan in a novel IgA nephropathy model identifies a susceptibility locus on murine chromosome 10, in a region syntenic to human IGAN1 on chromosome 6q22-23. J Am Soc Nephrol 2005;16:1289-1299.
6. Suzuki H, Suzuki Y, Tomino Y, et al: Bone marrow derived cell dependent IgA-IgG2a immune complex is involved in the pathogenesis of murine IgA nephropathy. Reported at the annual meeting of the American Society of Nephrology, St Louis, USA, 2004.
7. Shinkura R, Kitada K, Honjo T, et al: Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet 1999;22:74-77.
8. + B cells to the gut lamina propria. Proc Natl Acad Sci USA 2005;102:2482-2486.