ND4 mutation in transitional cell carcinoma: Does mitochondrial mutation occur before tumorigenesis?

Mitochondrion

Volumn 7, Issue 4, 2007, Pages 273-278

  Tzen, Chin Yuan ^a,b,c,d   Mau, Bey Liing ^e   Wu, Tsu Yen ^a  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b NURSING AND MANAGEMENT COLLEGE   (Taiwan)

^c NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e Sun Yat Sen Cancer Center   (Taiwan)

Author keywords

Mitochondrial DNA; Mutation; NADH dehydrogenase subunit 4; Transitional cell carcinoma

Indexed keywords

MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA SEQUENCE; FEMALE; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MITOCHONDRION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY ANALYSIS; SOFT TISSUE; TRANSITIONAL CELL CARCINOMA; URINARY TRACT; URINARY TRACT CANCER;

AGED; AGED, 80 AND OVER; AMINO ACIDS; BASE SEQUENCE; CARCINOMA, TRANSITIONAL CELL; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; MUTATION; NADH DEHYDROGENASE; NUCLEOTIDES;

EID: 34248655678     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2007.04.004     Document Type: Article

References (17)

1. Coller H.A., Khrapko K., Bodyak N.D., Nekhaeva E., Herrero-Jimenez P., and Thilly W.G. High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat. Genet. 28 (2001) 147-150
2. Conley Y.P., Brockway H., Beatty M., and Kerr M.E. Qualitative and quantitative detection of mitochondrial heteroplasmy in cerebrospinal fluid using denaturing high-performance liquid chromatography. Brain Res. Brain Res. Protoc. 12 (2003) 99-103
3. Fliss M.S., Usadel H., Caballero O.L., Wu L., Buta M.R., Eleff S.M., Jen J., and Sidransky D. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287 (2000) 2017-2019
4. Grzybowski T. Extremely high levels of human mitochondrial DNA heteroplasmy in single hair roots. Electrophoresis 21 (2000) 548-553
5. Jones J.B., Song J.J., Hempen P.M., Parmigiani G., Hruban R.H., and Kern S.E. Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations. Cancer Res. 61 (2001) 1299-1304
6. Liu V.W., Shi H.H., Cheung A.N., Chiu P.M., Leung T.W., Nagley P., Wong L.C., and Ngan H.Y. High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas. Cancer Res. 61 (2001) 5998-6001
7. Lo M.C., Lee H.M., Lin M.W., and Tzen C.Y. Analysis of heteroplasmy in hypervariable region II of mitochondrial DNA in maternally related individuals. Ann. N.Y. Acad. Sci. 1042 (2005) 130-135
8. Petros J.A., Baumann A.K., Ruiz-Pesini E., Amin M.B., Sun C.Q., Hall J., Lim S., Issa M.M., Flanders W.D., Hosseini S.H., Marshall F.F., and Wallace D.C. mtDNA mutations increase tumorigenicity in prostate cancer. Proc. Natl. Acad. Sci. USA 102 (2005) 719-724
9. Polyak K., Li Y., Zhu H., Lengauer C., Willson J.K., Markowitz S.D., Trush M.A., Kinzler K.W., and Vogelstein B. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat. Genet. 20 (1998) 291-293
10. Sharp M.G., Adams S.M., Walker R.A., Brammar W.J., and Varley J.M. Differential expression of the mitochondrial gene cytochrome oxidase II in benign and malignant breast tissue. J. Pathol. 168 (1992) 163-168
11. Shay J.W., and Werbin H. Are mitochondrial DNA mutations involved in the carcinogenic process?. Mutat. Res. 186 (1987) 149-160
12. Tan D.J., Bai R.K., and Wong L.J. Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res. 62 (2002) 972-976
13. Tzen C.Y., Huang Y.W., and Fu Y.S. Is atypical follicular adenoma of the thyroid a preinvasive malignancy?. Hum. Pathol. 34 (2003) 666-669
14. Wallace D.C. Mitochondrial diseases in man and mouse. Science 283 (1999) 1482-1488
15. Wilkie D., Evans I.H., Egilsson V., Diala E.S., and Collier D. Mitochondria, cell surface, and carcinogenesis. Int. Rev. Cytol. Suppl. 15 (1983) 157-189
16. Wong L.J., Lueth M., Li X.N., Lau C.C., and Vogel H. Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients. Cancer Res. 63 (2003) 3866-3871
17. Yeh J.J., Lunetta K.L., van Orsouw N.J., Moore Jr. F.D., Mutter G.L., Vijg J., Dahia P.L., and Eng C. Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene 19 (2000) 2060-2066