In vitro effects of bethanechol on intestinal smooth muscle preparations in presence and absence of M2 or M3 muscarinic receptor antagonists in healthy dairy cows

Deutsche Tierarztliche Wochenschrift

Volumn 114, Issue 5, 2007, Pages 171-177

  Zanolari, P ^a   Meylan, M ^a   Marti, M ^a   Keller, C ^b   Steiner, A ^a  

^a VETSUISSE FACULTY UNIVERSITY OF ZURICH   (Switzerland)

^b Tierarztpraxis Studer and Luder ^*  (Switzerland)

Author keywords

4 DAMP; AF DX 116; Bethanechol; Contractility; Dairy cow

Indexed keywords

BOS; BOVINAE;

EID: 34248647892     PISSN: 03416593     EISSN: None     Source Type: Journal    
DOI: 10.2377/0341-6593-114-171     Document Type: Article

References (43)

1. BRAUN, U., EICHER, R., HAUSAMMANN, K. (1989): Clinical findings in cattle with dilatation and torsion of the caecum. Vet. Rec. 125, 265-267.
2. BRUNNER, E., DOMHOF, S., LANGER, F. (2002): Nonparametric analysis of longitudinal data in factorial experiments, Wiley, New York.
3. CAULFIELD, M. P., BIRDSALL, N. J. (1998): International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol. Rev. 50, 279-290.
4. CHOPPIN, A., EGLEN, R. M. (2001): Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle. Br. J. Pharmacol. 133, 1035-1040.
5. DAVIS, L. E., KNIGHT, A. (1977): Review of the clinical pharmacology of the equine digestive system. J. Equine Med. Surg. 1, 27-35.
6. DIRKSEN, G. (1962): Die Blinddarmerweiterung und -drehung beim Rind. Dtsch. tierärztl. Wschr. 69, 409-416.
7. EGLEN, R. M. (2001): Muscarinic receptors and gastrointestinal tract smooth muscle function. Life Sci. 68, 2573-2578.
8. EGLEN, R. M., CHOPPIN, A., WATSON, N. (2001): Therapeutic opportunities from muscarinic receptor research. Trends Pharmacol. Sci. 22, 409-414.
9. EGLEN, R. M., HEGDE, S. S., WATSON, N. (1996): Muscarinic receptor subtypes and smooth muscle function. Pharmacol. Rev. 48, 531-565.
10. EGLEN, R. M., REDDY, H., WATSON, N. (1994): Selective inactivation of muscarinic receptor subtypes. Int. J. Biochem. 26, 1357-1368.
11. EHLERT, F. J., OSTROM, R.S., SAWYER, G. W. (1997): Subtypes of the muscarinic receptor in smooth muscle. Life Sci. 61, 1729-1740.
12. 3 muscarinic receptors in gastrointestinal smooth muscle. Life Sci. 64, 387-394.
13. EICHER, R., AUDIGÉ, E., BRAUN, U., BLUM, J., MEYLAN, M., STEINER, A. (1999): Epidemiologie und Risikofaktoren der Blinddarmdilatation und Labmagenverlagerung bei der Milchkuh. Schweiz. Arch. Tierheilkd. 141, 423-429.
14. FUBINI, S. L. (1990): Surgery of the bovine large intestine. Vet. Clin. North Am. Food Anim. Pract. 6, 461-471.
15. FUBINI, S. L., ERB, H. N., REBHUN, W. C., HORNE, D. (1986): Cecal dilatation and volvulus in daily cows: 84 cases (1977-1983). J. Am. Vet. Med. Assoc. 189, 96-99.
16. GIRALDO, E., MONFERINI, E., LADINSKY, H., HAMMER, R. (1987): Muscarinic receptor heterogeneity in guinea pig intestinal smooth muscle: binding studies with AF-DX116. Eur. J. Pharmacol. 141, 475-477.
17. HAMMER, R., GIRALDO, E., SCHIAVI, G. B., MONFERINI, E., LADINSKY, H. (1986): Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat. Life Sci. 38, 1653-1662.
18. HERLIHY, J. T., MURPHY, R. A. (1973): Length-Tension Relationship of Smooth Muscle of the Hog Carotid Artery. Circulation Research, Vol. XXXIII, September, 275-283.
19. HUNT, J. M., GERRING, E. L. (1985): Effects of autonomic agonists on equine gastrointestinal electromechanical activity. Proceedings Equine Colic Research Symposium, 210-213.
20. MANSFIELD, K.J., MITCHELSON, F. J., MOORE, K. H., BURCHER, E. (2003): Muscarinic receptor subtypes in the human colon: lack of evidence for atypical subtypes. Eur. J. Pharmacol. 482, 101-109.
21. MARTI, M., MEVISSEN, M., ALTHAUS, H., STEINER, A. (2005): in vitro effects of bethanechol on equine gastrointestinal contractility and functional characterization of involved muscarinic receptor subtypes. J. Vet. Pharmacol. Ther. 28, 565-574.
22. 3 subtype. Proc. Natl. Acad. Sci. USA 97, 9579-9584.
23. MICHEL, A., MEVISSEN, M., BURKHARDT, H. W., STEINER, A. (2003): in vitro effects of dsapride, metoclopramide and bethanechol on smooth muscle preparations from abomasal antrum and duodenum of dairy cows. J. Vet. Pharmacol. Ther. 26, 413-420.
24. PARKMAN, H. P., PAGANO, A. P., RYAN, J. P. (1999): Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions. Am. J. Physiol. 276, G1243-50.
25. PEARSON, H. (1963): Dilatation and torsion of the bovine caecum and colon. Vet. Rec. 75, 961-964.
26. PFEIFFER, J. B. R. (2006): in vitro effects of bethanechol on intestinal smooth muscle preparations from the duodenum and jejunum of healthy dairy cows, Doctoral thesis, Vetsuisse Faculty Berne.
27. PLUMB, D. C. (2002): Veterinary Drug Handbook. Fourth edition, Iowa State Press, Ames, 100-101.
28. RADOSTITS, O. (1960): Torsion of the cecum in cattle. Can. Vet. J. 1, 405-407.
29. RINGGER, N., LESTER, G. D., NEUWIRTH, L., MERRITT, A. M., VETRO, T., HARRISON, J. (1996): Effect of bethanechol or erythromycin on gastric emptying in horses. Am. J. Vet. Res. 57, 1771-1775.
30. STEINER, A., BRAUN, U., LISCHER, C., ISELIN, U. (1992a): Die chirurgische Behandlung der Blinddarmdilatation/-torsion bei der Kuh - 80 Fälle (1988-1990). Wien. Tierärztl. Mschr. 72, 41-46.
31. STEINER, A., DENAC, M., BALLINARI, U. (1992b): Effects of adrenaline, dopamine, serotonin, and different cholinergic agents on smooth muscle preparations from the ansa proximaus coli in cattle: studies in vitro. Zbl.Vet. Med. A 39, 541-547.
32. STEINER, A., MEYLAN, M., EICHER, R. (1999): Neue Erkenntnisse zur Ätiopathogenese und Behandlung der Blinddarmdilatation/-torsion bei der Kuh - Eine Übersicht. Schweiz. Arch. Tierheilkd. 141, 419-422.
33. STEINER, A., ROUSSEL, A. J., ELLIS, W. (1994): Colic motor complex of the cecum and proximal loop of the ascending colon in an experimental cow with large intestinal obstruction. J. Vet. Med. A 41, 53-61.
34. STEINER, A., ROUSSEL, A. J., MARTIG, J. (1995): Effect of bethanechol, neostygmine, metoclopramide, and propanolol on myoelectric activity of the ileocecocolic area in cows. Am. J. Vet. Res. 56, 1081-1086.
35. STENGEL, P. W., GOMEZA, J., WESS, J., COHEN, M. L. (2000): M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro. J. Pharmacol. Exp. Ther. 292, 877-885.
36. STOFFEL, M., MONNARD WICKI, C., MEVISSEN, M., STEINER, A., MEYLAN, M. (2006): Distribution of muscarinic receptor subtypes and of intestinal Cells of Cajal in the gastrointestinal tract of healthy dairy cows. Am. J. Vet. Res. 67, 1992-1997.
37. STOCKER, S., STEINER, A., GEISER, S., KÜNDIG, H. (1997): Myoelectric activity of the cecum and proximal loop of the ascending colon in cows after spontaneous cecal dilatation/dislocation. Am. J. Vet. Res. 58, 961-968.
38. SVENDSEN, P., KRISTENSEN, B. (1970): Cecal dilatation in cattle: An experimental study of the etiology. Nord. Vet. Med. 22, 578-583.
39. 2 muscarinic receptor in smooth muscle of guinea pig ileum. Mol. Pharmacol. 44, 102-110.
40. UCHIYAMA, T., CHESS-WILLIAMS, R. (2004): Muscarinic receptor subtypes of the bladder and gastrointestinal tract. J. Smooth Muscle Res. 40, 237-247.
41. UENO, T., DUENES, J. A., KOST, L. J., SARR, M. G. (2004): Contractile activity of mouse small intestinal longitudinal smooth muscle. J. Surg. Res. 118, 136-143.
42. WRZOS, H. F., TANDON, T., OUYANG, A. (2004): Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats. World J. Gastroenterol. 10, 3292-3298.
43. 3 subtypes. Mol. Pharmacol. 40, 943-951.