Usefulness of PCR strategies for early diagnosis of Chagas' disease reactivation and treatment follow-up in heart transplantation

American Journal of Transplantation

Volumn 7, Issue 6, 2007, Pages 1633-1640

  Diez, M ^a   Favaloro, L ^a   Bertolotti, A ^a   Burgos, J M ^a   Vigliano, C ^a   Lastra, M P ^a   Levin, M J ^a   Arnedo, A ^a   Nagel, C ^a   Schijman, A G ^a   Favaloro, R R ^a  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

Author keywords

Chagas' cardiomyopathy; Heart transplantation; kDNA PCR; Reactivation; SL DNA PCR

Indexed keywords

ANTIHISTAMINIC AGENT; AZATHIOPRINE; BENZNIDAZOLE; CALCINEURIN INHIBITOR; CYCLOSPORIN A; DNA; EVEROLIMUS; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY;

ACUTE GRAFT REJECTION; ADOLESCENT; ADULT; ARTICLE; CARDIAC GRAFT REJECTION; CHAGAS DISEASE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG ERUPTION; EARLY DIAGNOSIS; EXON; FEMALE; FOLLOW UP; GRAFT FAILURE; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; LEUKOPENIA; MALE; ORTHOTOPIC TRANSPLANTATION; PARASITE IDENTIFICATION; PATIENT MONITORING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REINFECTION; SAMPLE; SERODIAGNOSIS; TREATMENT RESPONSE;

EID: 34248639319     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.01820.x     Document Type: Article

References (34)

1. WHO Expert Committee on the Control of Chagas Disease (2000 Brasilia, Brasil) Control of Chagas Disease: Second report of the WHO expert committee. WHO Technical report series; 905
2. Storino R, Barragán H. Epidemiología. En: Storino R; Milei J. Enfermedad de Chagas. Buenos Aires : Doyma 1994 : 51 74.
3. Segura E, Ruiz M. Tripanosoma cruzi. En: Perea E. Enfermedades infecciosas y Microbiología Clínica. Buenos Aires : Doyma 1994 : 989.
4. UNDP/World Bank/WHO. Special Programme for Research and Training in Tropical Diseases. TRD News N°34, 1990.
5. Guzmán-Bracho C. Epidemiology of Chagas disease in México: An update. Trends in Parasitology 2001 17 : 372 377.
6. Kirchhoff L. American Trypanosomiasis (Chagaś Disease) - A tropical disease now in the United States. N Engl J Med 1993 329 : 639 644.
7. Hayes R, Schofield C. Estimación de las tasas de incidencia de infecciones y parasitosis crónicas a partir de la prevalencia: La enfermedad de Chagas en América Latina. Boletín de la Oficina Sanitaria Panamericana 1990 108 : 308 316.
8. Storino R Milei J. Vias de infección y aspectos clínicos. En: Storino R; Milei J. Enfermedad de Chagas. Buenos Aires : Doyma 1994 185 207.
9. Andrade Z : Períodos anatomo-clínicos de la enfermedad de Chagas. Reunión Internacional sobre Enfermedad de Chagas. Sociedad Argentina de Cardiología, Buenos Aires 1983.
10. Storino R, Milei J. Miocardiopatía chagásica crónica, un enfoque para el clínico general. Buenos Aires : Club de Estudio, 1980.
11. Bocchi E Fiorelli A. The Paradox of Survival Results after Heart Transplantation for Cardiomyopathy Caused by Trypanosoma cruzi. Ann Thorac Surg 2001 71 : 1833 1838.
12. Avila HA, Sigman DS, Cohen LM, Millikan RC, Simpson L. Polymerase chain reaction amplification of Trypanosoma cruzi kinetoplast minicircle DNA isolated from whole blood lysates: Diagnosis of chronic Chagaś disease. Mol Biochem Parasitol 1991 48 : 211 221.
13. Britto C, Cardoso MA, Wincker P, Morel CM. A simple protocol for the physical cleavage of Trypanosoma cruzi kinetoplast DNA present in blood samples and its use in polymerase chain reaction (PCR)-based diagnosis of chronic Chagas disease. Mem Inst Oswaldo Cruz, 1993 88 : 171 172.
14. Shumway N, Lower R. Transplantation of the heart. Adv Surg 1996 2 : 265 284.
15. Sarsan MA, Campell CS, Yonan NA, Deiraniya AK, Rahman AN. An alternative surgical technique in orthotopic cardiac transplantation. J Card Surg 1993 8 : 344 349.
16. Billingham ME, Cary NRB, Hammond EH et al. A Working Formulation for the Standardization of Nomenclature in the Diagnosis of Heart and Lung Rejection: Heart Rejection Study Group. J Heart Transplant 1990 9 : 587 593.
17. Strout RG. A method for concentrating hemoflagellates. J Parasitol 1962 48 : 100.
18. Freilij H Storino R. Diagnóstico de Laboratorio. En: Storino R; Milei J. Enfermedad de Chagas. Buenos Aires : Doyma 1994 343 357.
19. Riarte A, Luna C, Sabatiello R. Chagas disease in patients with kidney transplantation: 7 years of experience. Clin Infectious Diseases 1999 29 : 561 567.
20. Altclas J, Cíngara A, Dictar M et al. Chagas disease in bone marrow transplantation: An approach to preemptive therapy. Bone Marrow transplantation 2005 36 : 123 129.
21. Schijman A, Vigliano C, Burgos JM et al. Early diagnosis of recurrence of T. cruzi infection by polymerase chain reaction after heart transplantation of a chronic Chagaś heart disease patient. J Heart Lung Transplant, 2000 19 : 1114 1117.
22. Schijman A, Vigliano C, Viotti R et al. Trypanosoma cruzi DNA in cardiac lesions of Argentinean patients with end-stage chronic chagas heart disease. Am J Trop Med Hyg. 2004 70 : 210 220.
23. Burgos JM, Begher S, Freitas JM et al. Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral Chagas disease in a patient with AIDS. Am J Trop Med Hyg, 2005 73 : 1016 1018.
24. Marcet PL, Duffy T, Cardinal MV et al. PCR-based screening and lineage identification of Trypanosoma cruzi directly from faecal samples of triatomine bugs from northwestern Argentina. Parasitology. 2006 132 : 57 65.
25. Morris S, Tanowitz H, Wittner M, Bilezikian J Pathophysiological insights into the cardiomyopathy of Chagaś disease. Circulation 1990 82 : 1900 1909.
26. Guzzetti S, Iosa D, Pecis M, Bonura L, Prosdocimi M, Malliani A. Impaired Herat rate variability in patients with chronic Chagaśdisease. Am Heart J 1991 121 : 7.
27. Maldonado C, Albano S, Vettorazzi L et al. Using polymerase chain reaction in early diagnosis of re-activated Trypanososma cruzi infection after heart transplantation. J Heart Lung Transplant 2004 23 : 1345 1348.
28. Bacal F, Pereira Silva C, Bocchi E et al. Mychophenolate Mofetil increased Chagas Disease reactivation in heart transplanted patients: Comparison between two different protocols. American Journal of Transplantation 2005 5 : 2017 2021.
29. Kierszenbaum F, Cunha W, Beltz L, Sztein M. Trypanosomal immunosuppressive factor: A secretion products of T. cruzi that's inhibits proliferation and IL-2 receptor expression by activated human peripheral blood mononuclear cells. J Immunol. 1990 144 : 4000 4004.
30. Sinagra A, Riarte A, Lauricella M, Segura E. Reactivation of experimental chronic T. cruzi infection after immunosuppressive treatment by cyclosporin A and betametasone. Transplantation 1993 55 : 1431 1433.
31. Gluckstein D, Ciferri F, Ruskin J. Chagaś disease: Another cause of cerebral mass in the acquired immunodeficiency syndrome. Am J Med 1992 92 : 429 432.
32. Fiorelli A, Stolf N, Honorato R et al. Later evolution after cardiac transplantation in Chagaś disease. Transplantation Proceedings, 2005 37 : 2793 2798.
33. Sosa-Estani S, Armenti A, Araujo G et al. Tratamiento de la enfermedad de Chagas con Beznidazole y Acido Tioctico. Medicina 2004 64 : 1 6.
34. Rodolfo Viotti, Carlos Vigliano, Hector Armenti, Elsa Segura. Treatment of Chagaś disease with beznidazole: Clinical and serological evolution of patients with long term follow-up. Am Heart J 1994 127 : 151 162.