Mychophenolate mofetil increased Chagas disease reactivation in heart transplanted patients: Comparison between two different protocols

American Journal of Transplantation

Volumn 5, Issue 8, 2005, Pages 2017-2021

  Bacal, Fernando ^a   Silva, Christiano Pereira ^a   Bocchi, Edimar Alcides ^a   Pires, Philippe Vieira ^a   Moreira, Luiz Felipe P ^a   Issa, Victor Sarli ^a   Moreira, Silvia Ayub ^a   Das Dores Cruz, Fátima ^a   Strabelli, Tânia ^a   Stolf, Noedir Antonio Groppo ^a   Ramires, José Antonio Franchini ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Chagas cardiomyopathy; Heart transplantation; Immunosuppression; Reactivation

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISONE; THYMOCYTE ANTIBODY;

ADULT; ARTICLE; CARDIAC ALLOGRAFT VASCULOPATHY; CARDIOMYOPATHY; CHAGAS DISEASE; CLINICAL ARTICLE; CLINICAL PROTOCOL; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTERMETHOD COMPARISON; MALE; PATIENT MONITORING; PRIORITY JOURNAL; TREATMENT OUTCOME; TRYPANOSOMA CRUZI;

ADOLESCENT; ADULT; AGED; AZATHIOPRINE; CHAGAS CARDIOMYOPATHY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; RECURRENCE; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 22844442006     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2005.00975.x     Document Type: Article

References (21)

1. Bocchi EA, Fiorelli A. The paradox of survival results after heart transplantation for cardiomyopathy caused by Trypanosoma cruzi. Ann Thorac Surg 2001; 71: 1833-1838.
2. Centers for Disease Control and Prevention. Chagas disease after organ transplantation. JAMA 2002; 287: 1795-1796.
3. Canesin MF, Giorgi D, Oliveira MT et al. Ambulatory blood pressure monitoring of patients with heart failure. A new prognosis marker. Arq Bras Cardiol 2002; 78: 83-89.
4. Riarte A, Luna C, Sabatiello R et al. Chagas' disease in patients with kidney transplants: 7 years of experience 1989-1996. Clin Infect Dis 1999; 29: 561-567.
5. Vagelos R, Fowler MB. Selection of patients for cardiac transplantation. Cardiol Clin 1990; 8: 23-28.
6. Shumway NE, Lower RR. Transplantation of the heart. Adv Surg 1966; 2: 265-284.
7. Odorico JS, Pirsch JD, Knechtle SJ, D'Alessandro AM, Sollinger HW. A study comparing mycophenolate mofetil to azathioprine in simultaneous pancreas-kidney transplantation. Transplantation 1998; 66(12): 1751-1759.
8. Billingham ME. Endomyocardial biopsy diagnosis of acute rejection in cardiac allografts. Prog Cardiovasc Dis 1990; 33: 11-18.
9. Aretz HT. Myocarditis: the Dallas criteria. Hum Pathol 1987; 18: 619-624.
10. Bocchi EA, Fiorelli A. The brazilian experience with heart transplantation: a multicenter report. J Heart Lung Transplant 2001; 20: 637-645.
11. Bocchi EA, Bellotti G, Bacal F et al. Heart transplantation for chronic Chagas heart disease. Ann Thorac Surg 1996; 61: 1727-1733.
12. Malheiros SM, Gabbai AA, Brucki SM et al. Neurologic outcome after heart transplantation in Chagas' disease. Preliminary results. Acta Neurol Scand 1997; 96: 252-255.
13. Carvalho VB, Macruz R, Zerbini EJ†. Heart transplantation in Chagas disease. Circulation 1996; 94: 1815-1817.
14. Billingham ME, Gary NRB, Hamond ME et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: heart rejection study. J Heart Transplant 1990; 9: 587-593.
15. La Forgia MP, Pellerano G, de las Mercedes Portaluppi M et al. Cutaneous manifestation of reactivation of Chagas disease in a renal transplant patient: long-term follow-up. Arch Dermatol 2003; 139: 104-105.
16. Carvalho MF, de Franco MF, Soares VA. Amastigotes forms of Trypanosoma cruzi detected in a renal allograft. Rev Inst Med Trop Sao Paulo 1997; 39: 223-226.
17. Schijman AG, Vigliano C, Burgos J et al. Early diagnosis of recurrence 7 of Trypanosoma cruzi infection by polymerase chain reaction after heart transplantation of a chronic Chagas' heart disease patient. J Heart Lung Transplant 2000; 19: 1114-1117.
18. Blanche C, Aleksic I, Takkenberg JJ, Czer LS, Fishbein MC, Trento A. Heart transplantation for Chagas' cardiomyopathy. Ann Thorac Surg 1995; 60: 1406-1408 [Discussion 1408-1409].
19. I Guideline for heart transplantation of the Brazilian Society of Cardiology. Arq Bras Cardiol 1999; 73: 1-57.
20. Altclas J, Sinagra A, Jaimovich G et al. Reactivation of chronic Chagas disease following allogeneic bone marrow transplantation and successful pre-emptive therapy with benznidazole. Transpl Infect Dis 1999; 1: 135-137.
21. Almeida DR, Carvalho AC, Branco JN et al. Chagas' disease reactivation after heart transplantation: efficacy of allopurinol treatment. J Heart Lung Transplant 1996; 15: 988-992.