Preliminary studies of the physical stability of a glucagon-like peptide-1 derivate in the presence of metal ions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 66, Issue 3, 2007, Pages 366-371

  Christensen, Stina ^a   Moeller, Eva Horn ^b   Bonde, Claude ^a   Lilleoere, Anne Mette ^a  

^a NOVO NORDISK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Fourier transform infrared spectroscopy; GLP 1 derivate; Metal ions; Physical stability; Thioflavine T test; Tryptophan fluorescence

Indexed keywords

ALUMINUM; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; MAGNESIUM ION; METAL ION; POTASSIUM ION; THIOFLAVINE; TRYPTOPHAN; ZINC ION;

ALPHA HELIX; ARTICLE; BETA SHEET; CONCENTRATION RESPONSE; DRUG STABILITY; FLUORESCENCE ANALYSIS; INFRARED SPECTROSCOPY; LEACHING; NEPHELOMETRY; PHYSICAL CHEMISTRY; PROTEIN SECONDARY STRUCTURE;

ALUMINUM; DRUG STABILITY; GLUCAGON-LIKE PEPTIDE 1; MAGNESIUM; METALS; NEPHELOMETRY AND TURBIDIMETRY; POTASSIUM; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; ZINC;

EID: 34248597406     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.11.019     Document Type: Article

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