Characterisation of particle properties and compaction behaviour of hydroxypropyl methylcellulose with different degrees of methoxy/hydroxypropyl substitution

European Journal of Pharmaceutical Sciences

Volumn 9, Issue 2, 1999, Pages 171-184

  Gustafsson, Christina ^a   Bonferoni, Maria Cristina ^b   Caramella, Carla ^b   Lennholm, Helena ^c   Nyström, Christer ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF PAVIA   (Italy)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Compaction; HPMC; NMR; Particle shape; Substitution degree; Tablet

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; METHOCEL E4M; METHOCEL F4M; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; HYDROGEN BOND; MOISTURE; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; POROSITY; POWDER; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET THICKNESS; TENSILE STRENGTH;

COMPRESSIVE STRENGTH; DENSITOMETRY; ELASTICITY; LACTOSE; MAGNETIC RESONANCE SPECTROSCOPY; METHYLCELLULOSE; OXAZINES; POROSITY; POWDERS; SOLUBILITY; SURFACE PROPERTIES; TABLETS;

EID: 0033407637     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(99)00054-8     Document Type: Article

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