CNS germ cell tumor (CNSGCT) of childhood: Presentation and delayed diagnosis

Neurology

Volumn 68, Issue 20, 2007, Pages 1668-1673

  Crawford, J R ^a   Santi, M R ^b   Vezina, G ^b   Myseros, J S ^b   Keating, R F ^b   LaFond, D A ^b   Rood, B R ^b   MacDonald, T J ^b   Packer, R J ^b  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ANOREXIA; ARTICLE; BASAL GANGLION; BRAIN RADIOGRAPHY; BRAIN REGION; CANCER DIAGNOSIS; CENTRAL NERVOUS SYSTEM TUMOR; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CLINICAL FEATURE; DELAYED DIAGNOSIS; DIABETES INSIPIDUS; DISEASE DURATION; DISEASE FREE SURVIVAL; DISSEMINATED CANCER; ENDOCRINE DISEASE; ENURESIS; EYE DISEASE; FEMALE; GERM CELL TUMOR; GROWTH HORMONE DEFICIENCY; HEADACHE; HUMAN; HYPOTHYROIDISM; MALE; MENTAL DISEASE; MOTOR DYSFUNCTION; NAUSEA; NUCLEAR MAGNETIC RESONANCE IMAGING; OPHTHALMOLOGY; PATIENT ASSESSMENT; PINEAL BODY; PRIORITY JOURNAL; RADIODIAGNOSIS; SELLA TURCICA TUMOR; SYMPTOMATOLOGY; TEMPORAL LOBE; THALAMUS; TUMOR LOCALIZATION; VISUAL ACUITY; VISUAL DISORDER; VISUAL FIELD; VOMITING;

ADOLESCENT; AGE OF ONSET; ANOREXIA NERVOSA; BASAL GANGLIA DISEASES; BRAIN NEOPLASMS; CHILD; CHILD BEHAVIOR DISORDERS; CHILD, PRESCHOOL; DIAGNOSTIC ERRORS; DIAGNOSTIC IMAGING; DISEASE-FREE SURVIVAL; ENDOCRINE SYSTEM DISEASES; ENURESIS; FEMALE; FOLLOW-UP STUDIES; HEADACHE; HUMANS; HYDROCEPHALUS; KAPLAN-MEIERS ESTIMATE; MALE; MENTAL DISORDERS; MOVEMENT DISORDERS; NAUSEA; NEOPLASMS, GERM CELL AND EMBRYONAL; PINEALOMA; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; THALAMIC DISEASES; TREATMENT OUTCOME; VISION DISORDERS;

EID: 34248579296     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000261908.36803.ac     Document Type: Article

References (24)

1. Jennings MT, Gelman R, Hochberg F. Intracranial germ-cell tumors: natural history and pathogenesis. J Neurosurg 1985;63:155-167.
2. Araki C, Matsumoto S. Saishin Igaku [Latent intracranial tumors]. Recent Medicine 1969;24:1716-1720.
3. Yoshida J, Sugita K, Kobayashi T, et al. Prognosis of intracranial germ cell tumours: effectiveness of chemotherapy with cisplatin and etoposide (CDDP and VP-16). Acta Neurochirurgica 1993;120:111-117.
4. Matsutani M, Sano K, Takakura K, et al. Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg 1997;86:446-455.
5. Robertson PL, DaRosso RC, Allen JC. Improved prognosis of intracranial non-germinoma germ cell tumors with multimodality therapy. J Neuro-oncol 1997;32:71-80.
6. Engel U, Gottschalk S, Niehaus L, et al. Cystic lesions of the pineal region-MRI and pathology. Neuroradiology 2000;42:399-402.
7. Dearnaley DP, A'Hern RP, Whittaker S, Bloom HJ. Pineal and CNS germ cell tumors: Royal Marsden Hospital experience 1962-1987. Int J Radiat Oncol Biol Physics 1990;18:773-781.
8. Baranzelli MC, Patte C, Bouffet E, et al. Nonmetastatic intracranial germinoma: the experience of the French Society of Pediatric Oncology. Cancer 1997;80:1792-1797.
9. Shotelersuk K, Rojpornpradit P, Chottetanaprasit T, et al. Intracranial germ cell tumors: experience in King Chulalongkorn Memorial Hospital. J Med Assoc Thailand 2003;86:603-611.
10. Smith AA, Weng E, Handler M, Foreman NK. Intracranial germ cell tumors: a single institution experience and review of the literature. J Neuro-oncol 2004;68:153-159.
11. Wong LC, Yang TL, Gao F, Tan AM, Sethi VK, Chua EJ. Intracranial germ cell tumour: experience of a Singaporean institution over 11-year period. Singapore Med J 2002;43:182-188.
12. Chipkevitch E. Brain tumors and anorexia nervosa syndrome. Brain Dev 1994;16:175-179.
13. Mordecai D, Shaw RJ, Fisher PG, Mittelstadt PA, Guterman T, Donaldson SS. Case study: suprasellar germinoma presenting with psychotic and obsessive-compulsive symptoms [see comment]. J Am Acad Child Adolesc Psychiatry 2000;39:116-119.
14. Rushing EJ, Sandberg GD, Judkins AR, et al. Germinoma: unusual imaging and pathological characteristics. Report of two cases. J Neurosurg 2006;104:143-148.
15. Gottschling S, Graf N, Meyer S, Reinhard H, Krenn T, Rohrer T. Intracranial germinoma: a rare but important differential diagnosis in children with growth retardation. Acta Paediatr 2006;95:302-305.
16. Kellie SJ, Boyce H, Dunkel IJ, et al. Intensive cisplatin and cyclophosphamide-based chemotherapy without radiotherapy for intracranial germinomas: failure of a primary chemotherapy approach [see comment]. Pediatr Blood Cancer 2004;43:126-133.
17. Douglas JG, Rockhill JK, Olson JM, Ellenbogen RG, Geyer JR. Cisplatin-based chemotherapy followed by focal, reduced-dose irradiation for pediatric primary central nervous system germinomas. J Pediatr Hematol Oncol 2006;28:36-39.
18. Calaminus G, Bamberg M, Harms D, et al. AFP/beta-HCG secreting CNS germ cell tumors: long-term outcome with respect to initial symptoms and primary tumor resection. Results of the cooperative trial MAKEI 89. Neuropediatrics 2005;36:71-77.
19. Matsutani M, Takakura K, Sano K. Primary intracranial germ cell tumors: pathology and treatment. Progr Exp Tumor Res 1987;30:307-312.
20. Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O. Combined treatment with chemotherapy and radiation therapy for intracranial germ cell tumors. Childs Nerv Syst 1998;14:59-62.
21. Matsutani M. Japanese Pediatric Brain Tumor Study, G Combined chemotherapy and radiation therapy for CNS germ cell tumors-the Japanese experience. J Neuro-oncol 2001;54:311-316.
22. Modak S, Gardner S, Dunkel IJ, et al. Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumors. J Clin Oncol 2004;22:1934-1943.
23. Kellie SJ, Boyce H, Dunkel IJ, et al. Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocol. J Clin Oncol 2004;22:846-853.
24. Sawamura Y, Ikeda J, Shirato H, Tada M, Abe H. Germ cell tumours of the central nervous system: treatment consideration based on 111 cases and their long-term clinical outcomes. Eur J Cancer 1998;34:104-110.