Reduced response of splenocytes after mitogen-stimulation in the prion protein (PrP) gene-deficient mouse: PrPLP/Doppel production and cerebral degeneration

Biochemical and Biophysical Research Communications

Volumn 358, Issue 2, 2007, Pages 469-474

  Kim, Chi Kyeong ^a   Hirose, Yuko ^a   Sakudo, Akikazu ^a   Takeyama, Natsumi ^a   Kang, Chung Boo ^b   Taniuchi, Yojiro ^a   Matsumoto, Yoshitsugu ^a   Itohara, Shigeyoshi ^c   Sakaguchi, Suehiro ^d   Onodera, Takashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Institute of Animal Medicine   (South Korea)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Apoptosis; Prion disease; Prion protein; PrP deficient mice; Spleen

Indexed keywords

CONCANAVALIN A; IONOMYCIN; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PRION PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BRAIN CORTEX; BRAIN DEGENERATION; BRAIN NERVE CELL; CELL PROLIFERATION; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; MALE; MOUSE; NERVE CELL DEGENERATION; NEUROMODULATION; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; CEREBRAL CORTEX; LYMPHOCYTES; MICE; MICE, KNOCKOUT; MITOGENS; PRIONS;

MUS;

EID: 34248545152     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.04.174     Document Type: Article

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