A diplotype in the lymphotoxin alpha gene is associated with differential expression of LTA mRNA induced by Gram-positive and Gram-negative bacteria

International Journal of Immunogenetics

Volumn 34, Issue 3, 2007, Pages 157-160

  Temple, S E L ^a   Almeida, C M ^a   Cheong, K Y ^a   Wunderink, R G ^b   Waterer, G W ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOTOXIN; MESSENGER RNA;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE EXPRESSION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC LINKAGE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; ESCHERICHIA COLI; FEMALE; GENOTYPE; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; LYMPHOTOXIN-ALPHA; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; STREPTOCOCCUS PNEUMONIAE;

NEGIBACTERIA; POSIBACTERIA;

EID: 34248524055     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2007.00674.x     Document Type: Article

References (26)

1. Aggarwal, B.B., Henzel, W.J., Moffat, B., Kohr, W.J. Harkins, R.N. (1985) Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line. Journal of Biological Chemistry, 260, 2334.
2. Allcock, R.J., Windsor, L., Gut, I.G., Kucharzak, R., Sobre, L., Lechner, D., Garnier, J.G., Baltic, S., Christiansen, F.T. Price, P. (2004) High-density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging. Human Mutation, 24, 517.
3. Bouma, G., Crusius, J.B., Oudkerk, P.M., Kolkman, J.J., von Blomberg, B.M., Kostense, P.J., Giphart, M.J., Schreuder, G.M., Meuwissen, S.G. Pena, A.S. (1996) Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease. Scandinavian Journal of Immunology, 43, 456.
4. English, B.K., Burchett, S.K., English, J.D., Ammann, A.J., Wara, D.W. Wilson, C.B. (1988) Production of lymphotoxin and tumor necrosis factor by human neonatal mononuclear cells. Pediatrics Research, 24, 717.
5. Fang, X.M., Schroder, S., Hoeft, A. Stuber, F. (1999) Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis. Critical Care Medicine, 27, 1330.
6. Fu, Y.X., Huang, G., Wang, Y. Chaplin, D.D. (1998) B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion. Journal of Experimental Medicine, 187, 1009.
7. Hamid, Y.H., Urhammer, S.A., Glumer, C., Borch-Johnsen, K., Jorgensen, T., Hansen, T. Pedersen, O. (2005) The common T60N polymorphism of the lymphotoxin-alpha gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome. Diabetologia, 48, 445.
8. Heesen, M., Kunz, D., Bachmann-Mennenga, B., Merk, H.F. Bloemeke, B. (2003) Linkage disequilibrium between tumor necrosis factor (TNF)-alpha-308 G/A promoter and TNF-beta NcoI polymorphisms: association with TNF-alpha response of granulocytes to endotoxin stimulation. Critical Care Medicine, 31, 211.
9. Knight, J.C., Keating, B.J. Kwiatkowski, D.P. (2004) Allele- specific repression of lymphotoxin-alpha by activated B cell factor-1. Nature Genetics, 36, 394.
10. Leeper-Woodford, S.K., Carey, P.D., Byrne, K., Jenkins, J.K., Fisher, B.J., Blocher, C., Sugerman, H.J. Fowler, A.A. 3rd (1991) Tumor necrosis factor. Alpha and beta subtypes appear in circulation during onset of sepsis-induced lung injury. American Review of Respiratory Disease, 143, 1076.
11. Mackay, F. Browning, J.L. (1998) Turning off follicular dendritic cells. Nature, 395, 26.
12. Majetschak, M., Flohe, S., Obertacke, U., Schroder, J., Staubach, K., Nast-Kolb, D., Schade, F.U. Stuber, F. (1999) Relation of a TNF gene polymorphism to severe sepsis in trauma patients. Annals of Surgery, 230, 207.
13. Messer, G., Spengler, U., Jung, M.C., Honold, G., Blomer, K., Pape, G.R., Riethmuller, G. Weiss, E.H. (1991) Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production. Journal of Experimental Medicine, 173, 209.
14. Nedwin, G.E., Naylor, S.L., Sakaguchi, A.Y., Smith, D., Jarrett- Nedwin, J., Pennica, D., Goeddel, D.V. Gray, P.W. (1985) Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization. Nucleic Acids Research, 13, 6361.
15. Ozaki, K., Ohnishi, Y., Iida, A., Sekine, A., Yamada, R., Tsunoda, T., Sato, H., Hori, M., Nakamura, Y. Tanaka, T. (2002) Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nature Genetics, 32, 650.
16. Pierce, A.K., Reynolds, R.C. Harris, G.D. (1977) Leukocytic response to inhaled bacteria. American Review of Respiratory Disease, 116, 679.
17. Pociot, F., Briant, L., Jongeneel, C.V., Molvig, J., Worsaae, H., Abbal, M., Thomsen, M., Nerup, J. Cambon-Thomsen, A. (1993) Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. European Journal of Immunology, 23, 224.
18. Ross, P., Hall, L., Smirnov, I. Haff, L. (1998) High level multiplex genotyping by MALDI-TOF mass spectrometry. Nature Biotechnology, 16, 1347.
19. Sriskandan, S., Evans, T.J. Cohen, J. (1996a) Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma. Journal of Immunology, 156, 2430.
20. Sriskandan, S., Moyes, D., Lemm, G. Cohen, J. (1996b) Lymphotoxin-alpha (TNF-beta) during sepsis. Cytokine, 8, 933.
21. Stuber, F., Petersen, M., Bokelmann, F. Schade, U. (1996) A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis. Critical Care Medicine, 24, 381.
22. Temple, S.E., Cheong, K.Y., Almeida, C.M., Price, P. Waterer, G.W. (2003) Polymorphisms in lymphotoxin alpha and CD14 genes influence TNFalpha production induced by Gram-positive and Gram-negative bacteria. Genes Immunity, 4, 283.
23. Vial, W.C., Toews, G.B. Pierce, A.K. (1984) Early pulmonary granulocyte recruitment in response to Streptococcus pneumoniae. American Review of Respiratory Disease, 129, 87.
24. Waterer, G.W., ElBahlawan, L., Quasney, M.W., Zhang, Q., Kessler, L.A. Wunderink, R.G. (2003) Heat shock protein 70+1267 AA homozygotes have an increased risk of septic shock in adults with community-acquired pneumonia. Critical Care Medicine, 31, 1367.
25. Waterer, G.W., Quasney, M.W., Cantor, R.M. Wunderink, R.G. (2001) Septic shock and respiratory failure in community-acquired pneumonia have different TNF polymorphism associations. American Journal of Respiratory Critical Care Medicine, 163, 1599.
26. Zinetti, M., Agyekum, S., Evans, T., Polak, J. Cohen, J. (1998) The role of lipopolysaccharide, pro-inflammatory cytokines and bacterial superantigens in the transcriptional regulation of lymphotoxin alpha and beta in mouse splenocytes. Cytokine, 10, 940.