A polymorphism in the type one complement receptor (CR1) involves an additional cysteine within the C3b/C4b binding domain that inhibits ligand binding

Molecular Immunology

Volumn 44, Issue 14, 2007, Pages 3510-3516

  Birmingham, Daniel J ^a   Irshaid, Fawzi ^b   Gavit, Katherine F ^a   Nagaraja, Haikady N ^c   Yu, C Yung ^c   Rovin, Brad H ^a   Hebert, Lee A ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b AL AL BAYT UNIVERSITY   (Jordan)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Complement; CR1; Polymorphism; SLE

Indexed keywords

COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C4B; COMPLEMENT FACTOR I; CYSTEINE;

AFRICAN AMERICAN; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CAUCASIAN; COHORT ANALYSIS; COMPLEMENT FIXATION; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION; GENE FREQUENCY; HETEROZYGOTE; HUMAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; RACE DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; WILD TYPE;

AMINO ACID SEQUENCE; BASE SEQUENCE; COMPLEMENT C3B; COMPLEMENT C4B; CYSTEINE; CYTOSINE; GENE FREQUENCY; HUMANS; LIGANDS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, COMPLEMENT; REPETITIVE SEQUENCES, AMINO ACID; THYMINE;

SUGARCANE RAMU STUNT DISEASE PHYTOPLASMA;

EID: 34248523995     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.03.007     Document Type: Article

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