Abnormal permeability pathways in human red blood cells

Blood Cells, Molecules, and Diseases

Volumn 39, Issue 1, 2007, Pages 1-6

  Ellory, J C ^a   Robinson, H C ^a   Browning, J A ^a   Stewart, G W ^b   Gehl, K A ^a   Gibson, J S ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c Department of Veterinary Medicine ^*  (United Kingdom)

Author keywords

Band 3; Psickle; Permeability; Sickle cell disease; Stomatocytosis

Indexed keywords

CALCIUM; HEMOGLOBIN A; HEMOGLOBIN S; POTASSIUM; SODIUM;

ARTICLE; BLOOD OXYGENATION; CALCIUM CELL LEVEL; CALCIUM CONDUCTANCE; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE PERMEABILITY; DEOXYGENATION; ERYTHROCYTE MEMBRANE; HEMOLYSIS; OXYGEN TENSION; PATCH CLAMP; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RADIOISOTOPE DIAGNOSIS; SICKLE CELL ANEMIA; SODIUM TRANSPORT; STOMATOCYTOSIS; WHOLE CELL;

ANEMIA, SICKLE CELL; CALCIUM; CELL MEMBRANE PERMEABILITY; ERYTHROCYTE MEMBRANE; ERYTHROCYTES, ABNORMAL; HEMOGLOBIN, SICKLE; HUMANS; ION CHANNELS; ION TRANSPORT; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; POTASSIUM; SODIUM;

EID: 34248509091     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2007.02.011     Document Type: Article

References (54)

1. Tosteson D.C., and Hoffman J.F. Regulation of cell volume by active cation transport in high and low potassium sheep red cells. J. Gen. Physiol. 44 (1960) 169-194
2. Ellory J.C., and Lew V.L. Membrane Transport in Red Cells (1976), Academic Press, London
3. Kirk K. Membrane transport in the malaria-infected erythrocyte. Physiol. Rev. 81 (2001) 495-537
4. Brugnara C. Sickle cell disease. In: Bernhardt I., and Ellory J.C. (Eds). Red Cell Membrane Transport in Health and Disease (2004), Springer Verlag, Berlin 549-567
5. + transport. In: Bernhardt I., and Ellory J.C. (Eds). Red Cell Membrane Transport in Health and Disease (2003)
6. Staines H.M., Powell T., Ellory J.C., Egee S., Lapaix F., Decherf G., Thomas S.L.Y., Duranton C., Lang F., and Huber S.M. Modulation of whole-cell currents in Plasmodium falciparum-infected human red blood cells by holding potential and serum. J. Physiol. 552 (2003) 177-183
7. Desai S.A., Bezrukov S.M., and Zimmerberg J. A voltage-dependent channel involved in nutrient uptake by the red blood cells infected with the malaria parasite. Nature 406 (2000) 1001-1004
8. Duranton S.M., Huber S.M., and Lang F. Oxidation induces a Cl-dependent cation conductance in human red blood cells. J. Physiol. 539 (2002) 847-855
9. Dunham P.B., and Ellory J.C. Passive potassium transport in low potassium sheep red cells: dependence upon cell volume and chloride. J. Physiol. 318 (1981) 511-530
10. Speake P.F., Roberts C.A., and Gibson J.S. Effect of changes in respiratory blood parameters on equine red blood cell K-Cl cotransporter. Am. J. Physiol. 273 (1997) C1811-C1818
11. Pauling L., Itano H.A., Singer S.J., and Wells I.C. Sickle cell anaemia, a molecular disease. Science 110 (1949) 1141-1152
12. Ingram V.M. Gene mutations in human haemoglobin, the chemical difference between normal and sickle cell haemoglobin. Nature 180 (1957) 326-328
13. Bunn H.F., and Forget B.G. Hemoglobin: Molecular, Genetic and Clinical Aspects (1986), Saunders, Philadelphia
14. Eaton W.A., and Hofrichter J. Hemoglobin S gelation and sickle cell disease. Blood 70 (1987) 1245-1266
15. Hebbel R.P., Eaton J.W., Balasingam M., and Steinberg M.H. Spontaneous oxygen radical generation by sickle erythrocytes. J. Clin. Invest. 70 (1982) 1253-1259
16. Hebbel R.P., Morgan W.T., Eaton J.W., and Hedlund B.E. Accelerated autoxidation and heme loss due to instability of sickle hemoglobin. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 237-241
17. Hebbel R.P. Beyond hemoglobin polymerization: the red blood cell membrane and sickle cell disease pathophysiology. Blood 77 (1991) 214-237
18. Stuart J., and Ellory J.C. Rheological consequences of erythrocyte dehydration. Br. J. Haematol. 69 (1988) 1-4
19. Bookchin R.M., Ortiz O.E., and Lew V.L. Evidence for a direct reticulocyte origin of dense red cells in sickle cell anemia. J. Clin. Invest. 87 (1991) 113-124
20. Lew V.L., and Bookchin R.M. Ion transport pathology in the mechanism of sickle cell dehydration. Physiol. Rev. 85 (2005) 179-200
21. Brugnara C., Bunn H.F., and Tosteson D.C. Regulation of erythrocyte cation and water content in sickle cell anemia. Science 232 (1986) 388-390
22. Brugnara C. Sickle cell disease: from membrane pathophysiology to novel therapies for prevention of erythrocyte dehydration. J. Pediatr. Hematol./Oncol. 25 (2003) 927-933
23. Joiner C.H. Cation transport and volume regulation in sickle red blood cells. Am. J. Physiol. 264 (1993) C251-C270
24. 2+ permeability. J. Clin. Invest. 99 (1997) 2727-2735
25. Gardos G. The function of calcium and potassium permeability of human erythrocytes. Biochim. Biophys. Acta 30 (1958) 653-654
26. 2+ permeability in deoxygenated sickle cells. Blood 75 (1990) 2453-2458
27. + transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives. J. Clin. Invest. 92 (1993) 520-526
28. Ellory J.C., Hall A.C., and Stewart G.W. Volume-sensitive cation fluxes in mammalian red cells. Mol. Physiol. 8 (1985) 235-246
29. Ellory J.C., Player M., Chalder S.M., and Stuart J. Rheological effect of activation of the KCl-cotransport pathway in normal and sickle erythrocytes. Clin. Hemorheol. 9 (1989) 1009-1016
30. Pellegrino C.M., Rybicki A.C., Musto S., Nagel R.L., and Schwartz R.S. Molecular identification of erythroid K:Cl cotransporter in human and mouse erythroleukemic cells. Blood Cells Mol. Dis. 24 (1998) 31-40
31. Joiner C.H., Dew A., and Ge D.L. Deoxygenation-induced fluxes in sickle cells. I. Relationship between net potassium efflux and net sodium influx. Blood Cells 13 (1988) 339-348
32. Joiner C.H., Jiang M., and Franco R.S. Deoxygenation-induced cation fluxes in sickle cells IV. Modulation by external calcium. Am. J. Physiol. 269 (1995) C403-C409
33. Berkowitz L.R., and Orringer E.P. Passive sodium and potassium movements in sickle erythrocytes. Am. J. Physiol. 249 (1985) C208-C214
34. Bennekou P., and Christophersen P. Ion channels. In: Bernhardt I., and Ellory J.C. (Eds). Red Cell Membrane in Health and Disease (2003), Springer, Berlin 139-152
35. Tosteson D.C., Carlsen E., and Dunham E.T. The effects of sickling on ion transport. I. Effect of sickling on potassium transport. J. Gen. Physiol. 39 (1955) 31-53
36. Tosteson D.C. The effects of sickling on ion transport. II. The effect of sickling on sodium and cesium transport. J. Gen. Physiol. 39 (1955) 55-67
37. Clark M.R., and Rossi M.E. Permeability characteristics of deoxygenated sickle cells. Blood 76 (1990) 2139-2145
38. Joiner C.H., Morris C.L., and Cooper E.S. Deoxygenation-induced cation fluxes in sickle cells. III. Cation selectivity and response to pH and membrane potential. Am. J. Physiol. 264 (1993) C734-C744
39. Joiner C.H. Deoxygenation-induced cation fluxes in sickle cells: II. Inhibition by stilbene disulfonates. Blood 76 (1990) 212-220
40. Joiner C.H., Jiang M., Claussen W.J., Roszell N.J., Yasin Z., and Franco R.S. Dipyridamole inhibits sickling-induced cation fluxes in sickle red blood cells. Blood 97 (2001) 3976-3983
41. Bookchin R.M., Etzion Z., Sorette M.P., Mohandas N., and Lew V.L. Heterogeneity of ion transport in sickle cell anemia reticulocytes revealed by patterns of acid-induced dehydration. Blood 82 (1993) 350
42. Lew V.L., Tiffert T., Etzion Z., Perdomo D., Daw N., Macdonald L., and Bookchin R.M. Distribution of dehydration rates generated by maximal Gardos-channel activation in normal and sickle red blood cells. Blood 105 (2005) 361-367
43. Johnson R.M., and Gannon S.A. Erythrocyte cation permeability induced by mechanical stress: a model for sickle cell cation loss. Am. J. Physiol. 259 (1990) C746-C751
44. Egee S., Lapaix F., Decherf G., Staines H.M., Ellory J.C., Doerig C., and Thomas S.L. A stretch-activated anion channel is up-regulated by the malaria parasite Plasmodium falciparum. J. Physiol. 542 (2002) 795-801
45. Browning J.A., Ellory J.C., and Gibson J.S. Pathophysiology of red cell volume. Contrib. Nephrol. 152 (2006) 241-268
46. Browning J.A., Robinson H.C., Ellory J.C., and Gibson J.S. Deoxygenation-induced non-electrolyte pathway in red cells from sickle cell patients. Cell. Physiol. Biochem. 19 (2007) 165-174
47. Bernhardt I., Hall A.C., and Ellory J.C. Effects of low ionic strength media on passive human red cell monovalent cation transport. J. Physiol. 434 (1991) 489-506
48. Kirk K., Ellory J.C., and Young J.D. Transport of organic substrates via a volume-activated channel. J. Biol. Chem. 267 (1992) 23475-23478
49. Kirk K., Horner H.A., Elford B.C., Ellory J.C., and Newbold C.I. Transport of diverse substrates into malaria-infected erythrocytes via a pathway showing functional characteristics of a chloride channel. J. Biol. Chem. 269 (1994) 3339-3347
50. Bruce L.J., Ring S.M., Ridgewell K., Reardon D.M., Seymour C.A., Van Dort H.M., Low P.S., and Tanner M.J.A. South-east Asian ovalocytic (SAO) erythrocytes have a cold sensitive cation leak: implications for in vitro studies on stored SAO red cells. Biochim. Biophys. Acta 1416 (1999) 258-270
51. Culliford S.J., Bernhardt I., and Ellory J.C. Activation of a novel organic solute transporter in mammalian red cells. J. Physiol. 489 (1995) 755-765
52. Ellory J.C., Gibson J.S., and Stewart G.W. Pathophysiology of abnormal cell volume in human red cells. Contrib. Nephrol. 123 (1998) 220-239
53. Bruce L.J., Robinson H.C., Guizouarn H., Borgese F., Harrison P., King M.J., Goede J.S., Coles S.E., Gore D.M., Lutz H.U., et al. Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger AE1. Nat. Genet. 37 (2005) 1258-1263
54. Browning J.A., Staines H.M., Robsinson H.C., Powell T., Ellory J.C., and Gibson J.S. The effect of deoxygenation on whole-cell conductance of red blood cells from healthy individuals and patients with sickle cell disease. Blood 109 (2007) 2622-2629