Protective nature of Murraya koeninii leaves against hepatosuppression through antioxidant status in experimental rats

Pharmacologyonline

Volumn 1, Issue , 2007, Pages 232-242

  Gupta, R S ^a   Singh, Dharmendra ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

Author keywords

Carbon tetrachloride; Fat metabolism; Free radical quenching activity; Hepatic marker enzymes

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ALKALOID; ALPHA TOCOPHEROL; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; CATALASE; CHOLESTEROL; COPPER; GAMMA GLUTAMYLTRANSFERASE; GIRINIMBINE; IDITOL DEHYDROGENASE; IRON; ISOMAHANIMBINE; LACTATE DEHYDROGENASE; MAHANIMBINE; MAHANINE; METHANOL; MURRAYA KOENIGII EXTRACT; MURRAYAZOLIDINE; MURRAYAZOLINE; PLANT EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ZINC;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; DRUG STRUCTURE; ENZYME BLOOD LEVEL; EXPERIMENTAL STUDY; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID METABOLISM; LIPID PEROXIDATION; LIVER CELL MEMBRANE; LIVER PROTECTION; LIVER TOXICITY; MALE; MURRAYA; MURRAYA KOENIGII; NONHUMAN; PLANT LEAF; RAT; SOLVENT EXTRACTION; STATISTICAL SIGNIFICANCE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 34248390182     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Eaton DL, Gallagher EP, Bammler TK, Kunze KL. Role of cytochrome P-450 1A2 in chemical carcinogenesis: Implications for human variability in expression and enzyme activity. Pharmacogenetics 1995;5:259-274.
2. Prajapati ND, Purohit SS, Sharma AK, Kumar T. A Handbook of Medicinal Plants: A complete source Book. Agrobios, Jodhpur: India, 2003:352-353.
3. Tachibana Y, Kikuzaki H, Lajis NH, Nakatani N. Antioxidative activity of carbazoles from Murraya koenigii leaves. J Agric Food Chem 2001;49:5589-5594.
4. Narendhirakannan RT, Subramaniam S, Kandaswamy M. Mineral content of some medicinal plants used in the treatment of diabetes mellitus. Biol Trace Elem Res 2005;103:109-116.
5. Kesari AN, Gupta RK, Watal G. Hypoglycemic effects of Murraya koenigii on normal and alloxan-diabetic rabbits. J Ethnopharmacol 2005;97:247-251.
6. Tachibana Y, Kikuzaki H, Lajis NH, Nakatani N. Comparison of antioxidative properties of carbazole alkaloids from Murraya koenigii leaes. J Argic Food Chem 2003;51:6461-6467.
7. Zlatkis A, Zak B, Boyle AJ. A new method for the direct determination of cholesterol. J Lab Clin Med 1953;41:486-492.
8. Gottfried SP, Rosenberg B. Improved manual spectrophotometric procedure for determination of triglycerides. Clin Chem 1973;19:1077-1078.
9. Roe JH, Kuether CA. The determination of ascorbic acid in whole blood and urine through 2,4-DNPH derivative of dehydroascorbic acid. J Biochem 1943;147:399-407.
10. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal Biochem 1979;95:351-353.
11. Moron MS, Depierre JW, Mannervick B. Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochem Biophys Acta 1979;582:67-78.
12. Aebi H. Catalase in vitro. In: Colowick, SP, Kaplan, NO, editors. Methods in Enzymology. Vol. 105. Academic Press: New York, 1984: 121-126.
13. Marklund S, Marklund G. Involvement of superoxide anion radical in auto-oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-474.
14. Bishayee A, Sarkar A, Chatterjee M. Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver. J Ethnopharmacol 1995;47:69-74.
15. Bhatia AL, Jain M. Spinacia oleraceae L. Protects against gamma radiations: a study on glutathione and lipid peroxidation in mouse liver. Phytomedicine 2004;11:1-14.
16. Subrata De, Ravishankar B, Bhavsar GC. An investigation on the hepatoprotective activity of Gymnosporia montana. Plant Med 1994;60:301-304.
17. Shirwaikar A, Rajendran K, Kumar CD. In vitro antioxidant studies of Annona squamosa Linn. Leaves. Indian J Exp Biol 2004;42:803-807.
18. Bump EA, Brown JM. Role of glutathione in the radiation response of mammalian cells in vitro and in vivo. Pharmac Ther 1990;47:117-124.
19. Bronzetti G. Antimutagens in food. Trends Food Sci Technol 1994;5:390-396.