Avidity of the immunoglobulin G response to a Neisseria meningitidis group C polysaccharide conjugate vaccine as measured by inhibition and chaotropic enzyme-linked immunosorbent assays

Clinical and Vaccine Immunology

Volumn 14, Issue 4, 2007, Pages 397-403

  Harris, Shannon L ^a   Tsao, How ^a   Ashton, Lindsey ^b   Goldblatt, David ^b   Fernsten, Philip ^a  

^a WYETH RESEARCH   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

23 VALENT PNEUMOCOCCAL POLYSACCHARIDE VACCINE; IMMUNOGLOBULIN G; MENINGOCOCCUS VACCINE; MONOCLONAL ANTIBODY MNC207 3; MONOCLONAL ANTIBODY MNC46 1; PNEUMOCOCCAL CAPSULAR POLYSACCHARIDE VACCINE; POLYSACCHARIDE VACCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNIZATION; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL;

ANTIBODIES, BACTERIAL; ANTIBODY AFFINITY; ANTIGENS, BACTERIAL; BINDING SITES, ANTIBODY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN G; INFANT; MENINGOCOCCAL VACCINES; NEISSERIA MENINGITIDIS, SEROGROUP C; POLYSACCHARIDES, BACTERIAL; THIOCYANATES; VACCINES, CONJUGATE;

EID: 34248390155     PISSN: 15566811     EISSN: None     Source Type: Journal    
DOI: 10.1128/CVI.00241-06     Document Type: Article

References (34)

1. Anttila, M., J. Eskola, H. Ahman, and H. Kayhty. 1998. Avidity of IgG for Streptococcus pneumoniae type 6B and 23F polysaccharides in infants primed with pneumococcal conjugates and boosted with polysaccharide or conjugate vaccines. J. Infect. Dis. 177:1614-1621.
2. Anttila, M., J. Eskola, H. Ahman, and H. Kayhty. 1999. Differences in the avidity of antibodies evoked by four different pneumococcal conjugate vaccines in early childhood. Vaccine 17:1970-1977.
3. Anttila, M., M. Voutilainen, V. Jantti, J. Eskola, and H. Kayhty. 1999. Contribution of serotype-specific IgG concentration, IgG subclasses and relative antibody avidity to opsonophagocytic activity against Streptococcus pneumoniae. Clin. Exp. Immunol. 118:402-407.
4. Borrow, R., N. Andrews, D. Goldblatt, and E. Miller. 2001. Serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom: reevaluation of correlates of protection. Infect. Immun. 69:1568-1573.
5. Borrow, R., D. Goldblatt, N. Andrews, P. Richmond, J. Southern, and E. Miller. 2001. Influence of prior meningococcal C polysaccharide vaccination on the response and generation of memory after meningococcal C conjugate vaccination in young children. J. Infect. Dis. 184:377-380.
6. Borrow, R., D. Goldblatt, N. Andrews, J. Southern, L. Ashton, S. Deane, R. Morris, K. Cartwright, and E. Miller. 2002. Antibody persistence and immunological memory at age 4 years after meningococcal group C conjugate vaccination in children in the United kingdom. J. Infect. Dis. 186:1353-1357.
7. Borrow, R., D. Goldblatt, A. Finn, J. Southern, L. Ashton, N. Andrews, G. Lai, C. Riley, R. Rahim, K. Cartwright, G. Allan, and E. Miller. 2003. Immunogenicity of, and immunologic memory to, a reduced primary schedule of meningococcal C-tetanus toxoid conjugate vaccine in infants in the United Kingdom. Infect. Immun. 71:5549-5555.
8. Box, G. E. P., and D. R. Cox. 1964. An analysis of transformations. J. R. Stat. Soc. B 26:211-243.
9. Bundle, D. R., and B. W. Sigurskjold. 1994. Determination of accurate thermodynamics of binding by titration microcalorimetry. Methods Enzymol. 247:288-305.
10. Burrage, M., A. Robinson, R. Borrow, N. Andrews, J. Southern, J. Findlow, S. Martin, C. Thornton, D. Goldblatt, M. Corbel, D. Sesardic, K. Cartwight, P. Richmond, and E. Miller. 2002. Effect of vaccination with carrier protein on response to meningococcal C conjugate vaccines and value of different immunoassays as predictors of protection. Infect. Immun. 70:4946-4954.
11. Ekstrom, N., H. Ahman, J. Verho, J. Jokinen, M. Vakevainen, T. Kilpi, and H. Kayhty. 2005. Kinetics and avidity of antibodies evoked by heptavalent pneumococcal conjugate vaccines PncCRM and PncOMPC in the Finnish Otitis Media Vaccine Trial. Infect. Immun. 73:369-377.
12. Evans, S. V., B. W. Sigurskjold, H. J. Jennings, J. R. Brisson, R. To, W. C. Tse, E. Altman, M. Frosch, C. Weisgerber, H. D. Kratzin, et al. 1995. Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2→8)-polysialic acid. Biochemistry 34: 6737-6744.
13. Friguet, B., A. F. Chaffotte, L. Djavadi-Ohaniance, and M. E. Goldberg. 1985. Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J. Immunol. Methods 77:305-319.
14. Garcia-Ojeda, P. A., M. E. Monser, L. J. Rubinstein, H. J. Jennings, and K. E. Stein. 2000. Murine immune response to Neisseria meningitidis group C capsular polysaccharide: analysis of monoclonal antibodies generated in response to a thymus-independent antigen and a thymus-dependent toxoid conjugate vaccine. Infect. Immun. 68:239-246.
15. Giardina, P. C., R. E. Evans, D. J. Sikkema, D. Madore, and S. W. Hildreth. 2003. Effect of antigen coating conditions on enzyme-linked immunosorbent assay for detection of immunoglobulin G antibody to Neisseria meningitidis serogroup Y and W135 capsular polysaccharide antigens in serum. Clin. Diagn. Lab. Immunol. 10:1136-1140.
16. Giardina, P. C., E. Longworth, R. E. Evans-Johnson, M. L. Bessette, H. Zhang, R. Borrow, D. Madore, and P. Fernsten. 2005. Analysis of human serum immunoglobulin G against O-acetyl-positive and O-acetyl-negative serogroup W135 meningococcal capsular polysaccharide. Clin. Diagn. Lab. Immunol. 12:586-592.
17. Goldblatt, D., R. Borrow, and E. Miller. 2002. Natural and vaccine-induced immunity and immunologic memory to Neisseria meningitidis serogroup C in young adults. J. Infect. Dis. 185:397-400.
18. Granoff, D. M., and S. L. Harris. 2004. Protective activity of group C anticapsular antibodies elicited in two-year-olds by an investigational quadrivalent Neisseria meningitidis-diphtheria toxoid conjugate vaccine. Pediatr. Infect. Dis. J. 23:490-497.
19. Granoff, D. M., A. Morgan, and J. A. Welsch. 2005. Immunogenicity of an investigational quadrivalent Neisseria meningitidis-diphtheria toxoid conjugate vaccine in 2-year old children. Vaccine 23:4307-4314.
20. Gray, B. M., and D. R. Shaw. 1993. Artifacts with the thiocyanate elution method for estimating relative antibody avidity. J Immunol. Methods 157: 269-271.
21. Greenspan, N. S., and L. J. Cooper. 1993. Cooperative binding by mouse IgG3 antibodies: implications for functional affinity, effector function, and isotype restriction. Springer Semin. Immunopathol. 15:275-291.
22. Harris, S. L., W. J. King, W. Ferris, and D. M. Granoff. 2003. Age-related disparity in functional activities of human group C serum anticapsular antibodies elicited by meningococcal polysaccharide vaccine. Infect. Immun. 71:275-286.
23. Macdonald, R. A., C. S. Hosking, and C. L. Jones. 1988. The measurement of relative antibody affinity by ELISA using thiocyanate elution. J. Immunol. Methods 106:191-194.
24. McCloskey, N., M. W. Turner, and T. D. Goldblatt. 1997. Correlation between the avidity of mouse-human chimeric IgG subclass monoclonal antibodies measured by solid-phase elution ELISA and biospecific interaction analysis (BIA). J. Immunol. Methods 205:67-72.
25. Meikle, P. J., N. M. Young, and D. R. Bundle. 1990. O-antigen biotin conjugates. Preparation and use in direct competitive enzyme immunoassays. J. Immunol. Methods 132:255-261.
26. Pichichero, M. E., T. Voloshen, D. Zajac, and S. Passador. 1999. Avidity maturation of antibody to Haemophilus influenzae type b (Hib) after immunization with diphtheria-tetanus-acellular pertussis-Hib-hepatitis B combined vaccine in infants. J. Infect. Dis. 180:1390-1393.
27. Richmond, P., R. Borrow, D. Goldblatt, J. Findlow, S. Martin, R. Morris, K. Cartwright, and E. Miller. 2001. Ability of 3 different meningococcal C conjugate vaccines to induce immunologic memory after a single dose in UK toddlers. J. Infect. Dis. 183:160-163.
28. Richmond, P., D. Goldblatt, P. C. Fusco, J. D. Fusco, I. Heron, S. Clark, R. Borrow, and F. Michon. 1999. Safety and immunogenicity of a new Neisseria meningitidis serogroup C-tetanus toxoid conjugate vaccine in healthy adults. Vaccine 18:641-646.
29. Romero-Steiner, S., P. F. Holder, P. Gomez de Leon, W. Spear, T. W. Hennessy, and G. M. Carlone. 2005. Avidity determinations for Haemophilus influenzae Type b anti-polyribosylribitol phosphate antibodies. Clin. Diagn. Lab. Immunol. 12:1029-1035.
30. Sigurdardottir, S. T., K. Davidsdottir, V. A. Arason, O. Jonsdottir, and F. Laudat. 2005. Safety and immunogenicity of CRM197 conjugated 9-valent pneumococcal and meningococcal C combination vaccine (9vPnCMnCC) administrated in two or three primary doses in infancy, abstr. 288. Twenty-Third Annual Meeting of the European Society for Paediatric Infectious Diseases-ESPID, Valencia, Spain, 18 to 20 May, 2005.
31. Southern, J., S. Deane, L. Ashton, R. Borrow, D. Goldblatt, N. Andrews, P. Balmer, R. Morris, J. S. Kroll, and E. Miller. 2004. Effects of prior polysaccharide vaccination on magnitude, duration, and quality of immune responses to and safety profile of a meningococcal serogroup C tetanus toxoid conjugate vaccination in adults. Clin. Diagn. Lab. Immunol. 11:1100-1104.
32. Vorberg, E., and D. R. Bundle. 1990. Carbohydrate-enzyme conjugates for competitive EIA. J. Immunol. Methods 132:81-89.
33. Wiseman, T., S. Williston, J. F. Brandts, and L. N. Lin. 1989. Rapid measurement of binding constants and heats of binding using a new titration calorimeter. Anal. Biochem. 179:131-137.
34. Wuorimaa, T., R. Dagan, M. Vakevainen, F. Bailleux, R. Haikala, M. Yaich, J. Eskola, and H. Kayhty. 2001. Avidity and subclasses of IgG after immunization of infants with an 11-valent pneumococcal conjugate vaccine with or without aluminum adjuvant. J. Infect. Dis. 184:1211-1215.