Differences in the avidity of antibodies evoked by four different pneumococcal conjugate vaccines in early childhood

Vaccine

Volumn 17, Issue 15-16, 1999, Pages 1970-1977

  Anttila, Merja ^a   Eskola, Juhani ^a   Åhman, Heidi ^a   Käyhty, Helena ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Antibody avidity; Infants; Pneumococcal conjugate vaccines

Indexed keywords

BACTERIAL POLYSACCHARIDE; BACTERIAL PROTEIN; DIPHTHERIA TOXIN; DIPHTHERIA TOXOID; PNEUMOCOCCUS VACCINE; TETANUS TOXOID;

ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ARTICLE; BINDING AFFINITY; CLINICAL TRIAL; ENZYME IMMUNOASSAY; GEOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SERODIAGNOSIS; STREPTOCOCCUS PNEUMONIA; VACCINATION;

AGE FACTORS; ANALYSIS OF VARIANCE; ANTIBODIES, BACTERIAL; ANTIBODY AFFINITY; BACTERIAL VACCINES; HUMANS; IMMUNIZATION, SECONDARY; IMMUNOENZYME TECHNIQUES; IMMUNOGLOBULIN G; INFANT; POLYSACCHARIDES, BACTERIAL; STREPTOCOCCUS PNEUMONIAE; THIOCYANATES; TIME FACTORS; VACCINATION; VACCINES, CONJUGATE;

EID: 0033537870     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00458-7     Document Type: Article

References (16)

1. Stein K.E. Thymus-independent and thymus-dependent responses to polysaccharide antigens. J. Infect. Dis. 165 (Suppl. 1):1992;S49.
2. Berek C. The development of B-cells and the B-cell repertoire in the microenvironment of the germinal center. Immunol. Rev. 126:1992;5.
3. MacLennan I.C.M., Liu Y.-J., Johnson G.D. Maturation and dispersal of B-cell clones during T-cell-dependent antibody responses. Immunol. Rev. 126:1992;143.
4. Berek C., Berger A., Apel M. Maturation of the immune response in germinal centers. Cell. 67:1991;1121.
5. Agbarakwe A.E., Griffiths H., Begg N., Chapel H.M. Avidity of specific IgG antibodies elicited by immunization against Haemophilus influenzae type b. J. Clin. Pathol. 48:1995;206.
6. Avidity and bactericidal activity of antibody elicited by different Haemophilus influenzae type b conjugate vaccines. JAMA. 267:1992;1489-1494.
7. Granoff D.M., Lucas A.H. Laboratory correlates of protection against Haemophilus influenzae type b disease. Importance of assessment of antibody avidity and immunological memory. Ann. N. Y. Acad. Sci. 754:1995;278.
8. Lucas A.H., Granoff D.M. Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type b polysaccharide-protein conjugates. J. Immunol. 154:1995;4195.
9. Mäkelä PH, Eskola J, Käyhty H, Takala A. Vaccines against Haemophilus influenzae type b. In: Ala-Aldeen DA, Hormaeche CE, editors. Molecular and clinical aspects of bacterial vaccine development. John Wiley & Sons, 1995. p. 41-91.
10. Anttila M., Eskola J., Åhman H., Käyhty H. Avidity of IgG for Streptococcus pneumoniae type 6B and 23F polysaccharides in infants primed with pneumococcal conjugates and boosted with polysaccharide or conjugate vaccines. J. Infect. Dis. 177:1998;1614.
11. Käyhty H., Åhman H., Rönnberg P.-R., Tillikainen R., Eskola J. Pneumococcal polysaccharide-meningococcal outer membrane protein complex conjugate vaccine is immunogenic in infants and children. J. Infect. Dis. 172:1995;1273.
12. Åhman H., Käyhty H., Lehtonen H., Leroy O., Froeschle J., Eskola J. Streptococcus pneumoniae capsular polysaccharide-diphtheria toxoid conjugate vaccine is immunogenic in early infancy and able to induce immunologic memory. Pediatr. Infect. Dis. J. 17:1998;211.
13. Quataert S.A., Kirch C.S., Wiedl L.J., Phipps D.C., Strohmeyer S., Cimino C.O., Skuse J., Madore D.V. Assignment of weight-based antibody units to a human antipneumococcal standard reference serum, Lot 89-S. Clin. Diagn. Lab. Immunol. 2:1995;590.
14. Liu M., Friedman A., Oliff A., Tai J., Martinez D., Deck R., Shieh J., Jenkins T., Donnelly J., Hawe L. A Vaccine carrier derived from Neisseria meningitidis with mitogenic activity for lymphocytes. Proc. Natl. Acad. Sci. USA. 89:1992;4633.
15. Kurikka S., Käyhty H., Saarinen L., Rönnberg P.-R., Eskola J., Mäkelä P.H. Comparison of five different vaccination schedules with Haemophilus influenzae type b-tetanus toxoid conjugate vaccine. J. Pediatr. 128:1996;524.
16. Koskela M., Leinonen M., Häivä V.M., Timonen M., Mäkelä P.H. First and second dose antibody responses to pneumococcal polysaccharide vaccine in infants. Pediatr. Infect. Dis. 5:1986;45.