Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis

Clinical Genetics

Volumn 71, Issue 5, 2007, Pages 427-433

  Nielsen, M ^a   Hes, F J ^a   Nagengast, F M ^b   Weiss, M M ^a   Mathus Vliegen, E M ^c   Morreau, H ^a   Breuning, M H ^a   Wijnen, J T ^a   Tops, C M J ^a   Vasen, Hans F A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Adenomatous polyposis coli; Associated polyposis; Attenuated familial adenomatous polyposis; Colorectal cancer; MUTYH; MYH; Polyposis

Indexed keywords

APC PROTEIN; DNA GLYCOSYLASE MUTY;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; CLINICAL FEATURE; COLORECTAL CANCER; CONTROLLED STUDY; FAMILIAL COLON POLYPOSIS; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; NETHERLANDS; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; DNA GLYCOSYLASES; DNA MUTATIONAL ANALYSIS; GENES, APC; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; MIDDLE AGED; MUTATION; NETHERLANDS; REGISTRIES;

EID: 34248356377     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2007.00766.x     Document Type: Article

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