To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?

Critical Care

Volumn 11, Issue 1, 2007, Pages

  Li, Shi Sheng ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; ENDOTHELIAL PROTEIN C RECEPTOR; MYOSIN LIGHT CHAIN; PROTEIN ANTIBODY; PROTEINASE ACTIVATED RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR; PROTEIN C;

CELL CULTURE; CYTOSKELETON; DISEASE SEVERITY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LETTER; MEDICAL LITERATURE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SEPSIS; SIGNAL TRANSDUCTION; ENDOTHELIUM; METABOLISM; NOTE;

ENDOTHELIUM; HUMANS; PROTEIN C; RECEPTOR, PAR-1; RECEPTORS, LYSOSPHINGOLIPID; SEPSIS; SIGNAL TRANSDUCTION;

EID: 34248231205     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc5149     Document Type: Letter

References (5)

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5. Cheng T, Liu D, Griffin JH, Fernandez JA, Castellino F, Rosen ED, Fukudome K, Zlokovic BV. Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. Nat Med 2003, 9:338-342. 10.1038/nm826, 12563316.