Statins and intra-plaque angiogenesis in carotid artery disease

Atherosclerosis

Volumn 192, Issue 2, 2007, Pages 455-456

  Karthikeyan, V J ^a   Lip, Gregory Y H ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CERIVASTATIN; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; NITRIC OXIDE SYNTHASE; PRAVASTATIN; SIMVASTATIN; VASCULOTROPIN;

ALZHEIMER DISEASE; ANGIOGENESIS; CANCER RISK; CARDIOVASCULAR DISEASE; CAROTID ARTERY DISEASE; CELL MIGRATION; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; DIABETES MELLITUS; EDITORIAL; ENZYME ACTIVITY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MULTIPLE SCLEROSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; VASCULAR SURGERY;

CAROTID ARTERY DISEASES; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 34248229191     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.01.018     Document Type: Editorial

References (7)

1. Kurian K.C., Rai P., Sankaran S., et al. The effect of statins in heart failure: beyond its cholesterol-lowering effect. J Card Fail 12 (2006) 473-478
2. Inoue I., Goto S., Mizotani K., et al. Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. Life Sci. 67 (2000) 863-876
3. McCarthy M.J., Loftus I.M., Thompson M.M., et al. Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology. J Vasc Surg 30 (1999) 261-268
4. Blann A.D., Belgore F.M., Constans J., Conri C., and Lip G.Y. Plasma vascular endothelial growth factor and its receptor Flt-1 in patients with hyperlipidemia and atherosclerosis and the effects of fluvastatin or fenofibrate. Am J Cardiol 87 (2001) 1160-1163
5. Undas A., Celinska-Lowenhoff M., Stepien E., Nizankowski R., Tracz W., and Szczeklik A. Effects of simvastatin on angiogenic growth factors released at the site of microvascular injury. Thromb Haemost 95 (2006) 1045-1047
6. Lip G.Y., Blann A.D., and Thrombogenesis. atherogenesis and angiogenesis in vascular disease: a new 'vascular triad'. Ann Med 36 (2004) 119-125
7. Vincent L., Soria C., Mirshahi F., et al. Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models. Arterioscler Thromb Vasc Biol 22 (2002) 623-629