Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 4, 2002, Pages 623-629

  Vincent, Loïc ^a   Soria, Claudine ^a   Mirshahi, Farrokh ^a   Opolon, Paule ^a   Mishal, Zohair ^a   Vannier, Jean Pierre ^a   Soria, Jeannette ^a   Hong, Li ^a  

^a UFR Medecine et Pharmacie   (France)

Author keywords

Angiogenesis inhibition; RhoA; Statins; Vascular risk

Indexed keywords

ACTIN; ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR; CERIVASTATIN; CYCLIN DEPENDENT KINASE INHIBITOR; FARNESYL DIPHOSPHATE; FOCAL ADHESION KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MATRIGEL; MESSENGER RNA; PROTEIN KINASE B; PROTEIN P21; RHO FACTOR;

ANGIOGENESIS; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL CYCLE; CELL PROLIFERATION; CHICKEN; DEPOLYMERIZATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ARTERIOSCLEROSIS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENDOTHELIUM, VASCULAR; G1 PHASE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MICROCIRCULATION; NEOVASCULARIZATION, PATHOLOGIC; POLYISOPRENYL PHOSPHATES; PYRIDINES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 0036120428     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000012283.15789.67     Document Type: Article

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