Cytokine concentrations in bone marrow of stable sickle cell anemia patients

Journal of Investigative Medicine

Volumn 55, Issue 2, 2007, Pages 69-74

  Dallalio, Gail ^a   Brunson, Chris Y ^b   Means Jr , Robert T ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c LEXINGTON VA MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Cytokines; Erythropoiesis; Inflammation; Placental growth factor; Sickle cell anemia

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; PLACENTAL GROWTH FACTOR; TRANSFERRIN RECEPTOR; TUMOR NECROSIS FACTOR;

ARTICLE; BONE MARROW; BONE MARROW BIOPSY; CLINICAL ARTICLE; COLONY FORMING UNIT E; CONTROLLED STUDY; ERYTHROPOIESIS; HOMOZYGOSITY; HUMAN; SICKLE CELL ANEMIA;

EID: 34248211641     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: 10.2310/6650.2007.06029     Document Type: Article

References (29)

1. Chies JA, Nardi NB. Sickle cell disease: a chronic inflammatory condition. Med Hypotheses 2001:57:46-50.
2. Hebbel RP, Osarogiagbon R, Kaul D. The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy. Microcirculation 2004;11:129-51.
3. Miller ST, Sleeper LA, Pegelow CH, et al. Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med 2000;342:83-9.
4. Platt OS. Sickle cell anemia as an inflammatory disease. J Clin Invest 2000;106:337-8.
5. Wun T. The role of inflammation and leukocytes in the pathogenesis of sickle cell disease. Hematology 2001;5:403-12.
6. Bourantas KL, Dalekos GN, Makis A, et al. Acute phase proteins and interleukins in steady state sickle cell disease. Eur J Haematol 1998;61:49-54.
7. Croizat H. Circulating cytokines in sickle cell patients during steady state. Br J Haematol 1994;87:592-7.
8. Hibbert JM, Hsu LL, Bhathena SJ, et al. Proinflammatory cytokines and the hypermetabolism of children with sickle cell disease. Exp Biol Med (Maywood) 2005;230:68-74.
9. Taylor SC, Shacks SJ, Qu Z, Wiley P. Type 2 cytokine serum levels in healthy sickle cell disease patients. J Natl Med Assoc 1997;89:753-7.
10. Dallalio G, North M, McKenzie SW, Means RT. Cytokine and cytokine receptor concentrations in bone marrow supernatant from patients with HIV: correlation with hematologic parameters. J Invest Med 1999;47:477-83.
11. Jongen-Lavrenic H, Peeters HR, Wognum A, et al. Elevated levels of inflammatory cytokines in bone marrow of patients with rheumatoid arthritis and anemia of chronic disease. J Rheumatol 1997;24:1504-9.
12. Lichtenstein A, Berenson J, Norman D, et al. Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood 1989;74:1266-73.
13. McLeod DL, Shreeve MM, Axelrad AA. Improved plasma culture system for production of erytrocytic colonies in vitro: quantitative assay method for CFU-E. Blood 1974; 44:517-34.
14. Eaves AC, Eaves CJ. Erythropoiesis in culture. Clin Haematol 1984;13:371-91.
15. Cazzola M, Guarnone R, Cerani P, et al. Red blood cell precursor mass as an independent determinant of serum erythropoietin level. Blood 1998;91:2139-45.
16. Beguin Y, Clemons GK, Pootrakul P, Fillet G. Quantitative assessment of erythropoiesis and functional classification of anemia based on measurements of serum transferrin receptor and erythropoietin. Blood 1993;81:1067-76.
17. Perelman N, Selvaraj SK, Batra S, et al. Placenta growth factor activates monocytes and correlates with sickle cell disease activity. Blood 2003:102:1506-14.
18. Selvaraj SK, Giri RK, Perelman N, et al. Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. Blood 2003; 102:1515-24.
19. Pennathur-Das R, Alpen E, Vichinsky E, et al. Evidence for the presence of CFU-E with increased in vitro sensitivity to erythropoietin in sickle cell anemia. Blood 1984;63:1168-71.
20. Croizat H, Ponchio L, Nicolini FE, et al. Primitive haematopoietic progenitors in the blood of patients with sickle cell disease appear to be endogenously mobilized. Br J Haematol 2000;111:491-7.
21. Dallalio G, North M, Means RT. Inhibition of marrow CFU-E colony formation from human immunodeficiency virus-infected patients by β- and γ-interferon. Am J Hematol 1996;53:118-20.
22. Selvaraj SK, Gin RK, Perelman N, et al. Mechanism of monocyte activation and expression of proinflammatory cytokines by placenta growth factor. Blood 2003:102:1515-24.
23. Duits AJ, Rodriguez T, Schnog J-JB. Scrum levels of angiogenic factors indicate a pro-angiogenic state in adults with sickle cell disease. Br J Haematol 2006;134:116-9.
24. Singhal A, Cook JD, Skikne BS, et al. The clinical significance of serum transferrin receptor levels in sickle cell disease. Br J Haematol 1993;84:301-4.
25. Tancabelic J, Sheth S, Paik M, Piomelli S. Serum transferrin receptor as a marker of erythropoiesis suppression in patients on chronic transfusion. Am J Hematol 1999;60: 121-5.
26. Vercellotti GM. PIGF: a link between inflammation and angiogenesis in sickle disease. Blood 2003:102:1153.
27. Means RT. Recent developments in the anemia of chronic disease. Curr Hematol Rep 2003;2:116-21.
28. Murakami M, Iwai S, Hiratsuka S, et al. Signaling of vascular endothelial growth factor receptor- 1 tyrosine kinase promotes rheumatoid arthritis through activation of monocyte/macrophages. Blood 2006. [Epub May 18, 2006].
29. Errico M, Riccioni T, Iyer S, et al. Identification of placenta growth factor determinants for binding and activation of Flt-1 receptor. J Biol Chem 2004:279: 43929-39.