Cytokine and cytokine receptor concentrations in bone marrow supernatant from patients with HIV: Correlation with hematologic parameters

Journal of Investigative Medicine

Volumn 47, Issue 9, 1999, Pages 477-483

  Dallalio, Gail ^a,b   North, Melissa ^b   McKenzie, Stacey W ^a,b   Means Jr , Robert T ^b,c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Cytokines; Human immunodeficiency virus; Macrophage inflammatory protein; RANTES; Tumor necrosis factor

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS;

BIOLOGICAL MARKER; CYTOKINE; CYTOKINE RECEPTOR;

ADULT; ARTICLE; BONE MARROW; COMPARATIVE STUDY; DIFFERENTIAL DIAGNOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; METABOLISM; MIDDLE AGED; NEEDLE BIOPSY; PATHOLOGY;

ADULT; BIOLOGICAL MARKERS; BIOPSY, NEEDLE; BONE MARROW; CYTOKINES; DIAGNOSIS, DIFFERENTIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; RECEPTORS, CYTOKINE; SEVERITY OF ILLNESS INDEX;

EID: 0033227670     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Sullivan PS, Hanson DL, Chu SY, Jones JL, Ward JW, Adult/Adolescent Spectrum of Disease Group. Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the Adult/Adolescent Spectrum of HIV Disease Surveillance Project. Blood 1998;91:301-8.
2. Zon LI, Arkin C, Groopman JE. Hematologic manifestations of the human immunodeficiency virus (HIV). Br J Haematol 1987;66:251-56.
3. Richman DD, Fischl MA, Grieco MH, Gottlieb MS, Volberding PA, Laskin OL, Leedom JM, Groopman JE, Mildvan D, Hirsch MS, Jackson GG, AZT Collaborative Working Group. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987;317:192-97.
4. Spivak JL, Barnes DC, Fuchs E, Quinn TC. Serum immunoreactive erythropoietin in HIV-infected patients. JAMA 1989;261:3104-7.
5. Fischl M, Galpin JE, Levine JD, Groopman JE, Henry DH, Kennedy P, Miles S, Robbins W, Starrett B, Zalusky R, Abels RI, Tsai HC, Rudnick SA. Recombinant human erythropoietin for patients with AIDS treated with zidovudine. N Engl J Med 1990;322:1488-93.
6. Re MC, Zauli G, Furlini G, Raineri S, Monari P, Ramazzoti E, LaPlaca M. The impaired number of circulating granulocyte/macrophage progenitors in human immunodeficiency virus type-1 correlates with an active HIV-1 replication. Arch Virol 1993;129:53-64.
7. Stella CC, Ganser A, Hoelzer D. Defective in vitro growth of the hemopoietic progenitor cells in the acquired immunodeficiency syndrome. J Clin Invest 1987;80:286-93.
8. Fuchs D, Zangerle R, Artner-Dworzak E, Weiss G, Fritsch P, Tilz GP, Dierich MP, Wachter H. Association between immune activation, changes of iron metabolism, and anaemia in patients with HIV infection. Eur J Haematol 1993;50:90-94.
9. Karcher DS, Frost AR. The bone marrow in human immunodeficiency virus (HIV) related disease. Morphology and clinical correlation. Am J Clin Pathol 1991;95:63-71.
10. Lepe-Zuniga JL, Mansell PWA, Hersh EM. Idiopathic production of interleukin-1 in acquired immune deficiency syndrome. J Clin Micro 1987;25:1695-1700.
11. Means RT, Krantz SB. Progress in understanding the pathogenesis of the anemia of chronic disease. Blood 1992;80:1639-47.
12. Means RT. Cytokines and anaemia in human immunodeficiency virus infection. Cytokines, Cellular and Molecular Therapy 1997;3:179-86.
13. Wright SC, Jewett A, Mitsuyasu R, Bonavida B. Spontaneous cytotoxicity and tumor necrosis factor production by peripheral blood monocytes from AIDS patients. J Immunol 1988;141:99-104.
14. Kalinkovich A, Engelmann H, Harpaz N, Burstein R, Barak V, Kalickman I, Wallach D, Bentwich Z. Elevated serum levels of soluble tumor necrosis factor receptors (sTNF-R) in patients with HIV infection. Clin Exp Immunol 1992;89:351-55.
15. Cope AP, Aderka D, Doherty M, Engelmann H, Gibbons D, Jones AC, Brennan FM, Maini RN, Wallach D, Feldmann M. Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. Arthritis Rheum 1992;35:1166-69.
16. Maury CPJ, Lahdevirta J. Correlation of serum cytokine levels with haematological abnormalities in human immunodeficiency virus infection. J Intern Med 1990;227:253-57.
17. Molina J-M, Scadden DT, Byrn R, Dinarello CA, Groopman JE. Production of tumor necrosis factor a and interleukin 1 by monocytic cells infected with human immunodeficiency virus. J Clin Invest 1989;84:733-37.
18. Berman MA, Sandborg CI, Calabia BS, Andrews BS, Friou GJ. Interleukin-1 inhibitor masks high interleukin 1 production in acquired immunodeficiency syndrome (AIDS). Clin Immunol Immunopathol 1987;42:133-40.
19. Roux-Lombard P, Aladjem D, Balavoine J-F, Chofflon M, Despont J-P, Hirschel B, Jennet M, Kapanci Y, Lang R, Toccanier M-F, Voiners B, Wilhelm A, Dayer J-M, Cruchand A. Altered functions of peripheral blood monocytes in homosexual males and intravenous drug users with persistent generalized lymphadenopathy. Eur J Clin Invest 1986;16:262-70.
20. Enk C, Gersoft J, Moller S, Remvig L. Interleukin 1 activity in the acquired immunodeficiency syndrome. Scand J Immunol 1986;23:491-97.
21. Murray HW, Rubin BY, Masur H, Roberts RB. Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome. N Engl J Med 1984;310:883-89.
22. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P. Identification of RANTES, MIP-1α, and MIP-1 as the major HIV-suppressive factors produced by CD8+ T cells. Science 1995;270:1811-15.
23. Verfaillie CM. Chemokines as inhibitors of hematopoietic progenitors. J Lab Clin Med 1996;127:148-50.
24. Suter PM, Suter S, Girardin E, Roux-Lombard P, Grau GE, Dayer JM. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am Rev Resp Dis 1992;145:1016-22.
25. Griffin DE, McArthur JC, Cornblath DR. Neopterin and interferon gamma in serum and cerebrospinal fluid of patients with HIV-associated neurologic disease. Neurology 1991;41:69-74.
26. Hirayama Y, Sakamaki S, Matsunaga T, Kuga T, Huroda H, Kusakabe T, Sasaki K, Fujiwaka K, Kato J, Kogawa K, Koyama R, Niitsu Y. Concentrations of thrombopoietin in bone marrow in normal subjects and in patients with idiopathic thrombocytopenia purpura, aplastic anemia, and essential thrombocythemia correlate with its mRNA expression of bone marrow stromal cells. Blood 1998;92:46-52.
27. Cluitmans FHM, Esendam BHJ, Landegent JE, Willemze R, Falkenberg JHF. Constituitive in vivo cytokine and hematopoietic growth factor gene expression in the bone marrow and peripheral blood of healthy individuals. Blood 1995;85:2038-44.
28. Glantz SA. Primer of biostatistics. 3rd ed. New York: McGraw Hill, 1992.
29. Centers for Disease Control. 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. JAMA 1993;269:729-30.
30. Means RT, Dessypris EN, Krantz SB. Inhibition of human colony-forming units erythroid by tumor necrosis factor requires accessory cells. J Clin Invest 1990;86:538-41.
31. Means RT, Krantz SB. Inhibition of human erythroid colony-forming units by tumor necrosis factor requires beta interferon. J Clin Invest 1993;91:416-19.
32. Peetre C, Gullberg U, Nilsson E, Olsson I. Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relation to cell surface receptors. J Clin Invest 1986;78:1694-1700.
33. Roodman GD, Bird A, Hutzler D, Montgomery W. Tumor necrosis factor-alpha and hematopoietic progenitors: effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines K562, HL60, HEL cells. Exp Hematol 1987;15:928-35.
34. Blick M, Sherwin SA, Rosenblum M, Gutterman I. Phase I study of recombinant tumor necrosis factor in cancer patients. Cancer Res 1987;47:2986-89.
35. Ebrahim O, Folb PI, Robson SC, Jacobs P. Blunted erythropoietin response to anaemia in tuberculosis. Eur J Haematol 1995;55:251-54.
36. Elliott MJ, Maini RN, Feidmann M, Long-Fox A, Charles P, Bijl H, Woody JN. Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 1994;344:1125-27.
37. Alkhatib G, Conbadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA. CC CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 1996;272:1955-58.
38. Jansson M, Popovic M, Karlsson A, Cocchi F, Rossi P, Albert J, Wigzell H. Sensitivity to inhibition by Beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates. Proc Natl Acad Sci USA 1996;93:15382-87.
39. Mayani H, Little M-T, Dragowska W, Thornbury G, Lansdorp PM. Differential effects of the hematopoietic inhibitors MIP-1α, TGF-β, and TNF-α on cytokine-induced proliferation of subpopulations of CD34+ cells purified from cord blood and fetal liver. Exp Hematol 1995;23:422-27.
40. Gautam S, Noth CJ, Janakiraman N, Pindolia KR, Chapman RA. Induction of chemokine mRNA in bone marrow stromal cells: modulation by TGF-β1 and IL-4. Exp Hematol 1995;23:482-91.