-
1
-
-
34248206072
-
Glucagon-like peptide-1: A novel therapeutic agent for the treatment of type 2 diabetes
-
Brubaker PL. Glucagon-like peptide-1: a novel therapeutic agent for the treatment of type 2 diabetes. Can J Diab Care 1999; 23: 39-46
-
(1999)
Can J Diab Care
, vol.23
, pp. 39-46
-
-
Brubaker, P.L.1
-
2
-
-
0031936954
-
Glucagon-like peptides
-
Drucker DJ. Glucagon-like peptides. Diabetes 1997; 47: 159-69
-
(1997)
Diabetes
, vol.47
, pp. 159-169
-
-
Drucker, D.J.1
-
3
-
-
0038202937
-
Antihypertensive effect of glucagon-like peptide 1 in Dahl salt-sensitive rats
-
Yu M, Moreno C, Hoagland KM, et al. Antihypertensive effect of glucagon-like peptide 1 in Dahl salt-sensitive rats. J Hypertension 2003; 21: 1125-35
-
(2003)
J Hypertension
, vol.21
, pp. 1125-1135
-
-
Yu, M.1
Moreno, C.2
Hoagland, K.M.3
-
4
-
-
0036307872
-
Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
-
Yamamoto H, Lee CE, Marcus JN, et al. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest 2002; 110: 43-52
-
(2002)
J Clin Invest
, vol.110
, pp. 43-52
-
-
Yamamoto, H.1
Lee, C.E.2
Marcus, J.N.3
-
5
-
-
0029954211
-
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide 1 (7-36) amide in type 1 diabetic patients
-
Creutzfeldt WO, Kleine N, Willms B, et al. Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide 1 (7-36) amide in type 1 diabetic patients. Diabetes Care 1996; 19: 580-6
-
(1996)
Diabetes Care
, vol.19
, pp. 580-586
-
-
Creutzfeldt, W.O.1
Kleine, N.2
Willms, B.3
-
6
-
-
0026596851
-
Antidiabetogenic effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus
-
Gutniak M, Orskov C, Holst JJ, et al. Antidiabetogenic effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus. N Engl J Med 1992; 326: 316-22
-
(1992)
N Engl J Med
, vol.326
, pp. 316-322
-
-
Gutniak, M.1
Orskov, C.2
Holst, J.J.3
-
7
-
-
0028889380
-
Enteral enhancement of glucose disposition by both insulin-dependent and insulin-independent processes: A physiological role of glucagon-like peptide 1
-
D'Alessio DA, Prigeon RL, Ensinck JW. Enteral enhancement of glucose disposition by both insulin-dependent and insulin-independent processes: a physiological role of glucagon-like peptide 1. Diabetes 1995; 44: 1433-7
-
(1995)
Diabetes
, vol.44
, pp. 1433-1437
-
-
D'Alessio, D.A.1
Prigeon, R.L.2
Ensinck, J.W.3
-
8
-
-
0032005005
-
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
-
Flint A, Raben A, Astrup A, et al. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998; 101: 515-20
-
(1998)
J Clin Invest
, vol.101
, pp. 515-520
-
-
Flint, A.1
Raben, A.2
Astrup, A.3
-
9
-
-
0030068620
-
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
-
Willms B, Werner J, Holst JJ, et al. Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. J Clin Endocrinol Metab. 1996; 81: 327-32
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 327-332
-
-
Willms, B.1
Werner, J.2
Holst, J.J.3
-
10
-
-
0029857454
-
The antidiabetogenic effect of GLP-1 is maintained during a 7-day treatment period and improves diabetic dyslipoproteinemia in NIDDM patients
-
Juntti-Berggren L, Pigon J, Karpe F, et al. The antidiabetogenic effect of GLP-1 is maintained during a 7-day treatment period and improves diabetic dyslipoproteinemia in NIDDM patients. Diabetes Care. 1996; 19: 1200-6
-
(1996)
Diabetes Care
, vol.19
, pp. 1200-1206
-
-
Juntti-Berggren, L.1
Pigon, J.2
Karpe, F.3
-
11
-
-
33644840976
-
Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus
-
De Leon DD, Crutchlow MF, Ham JYN, et al. Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus. Int J Biochem Cell Biol 2006; 38: 845-59
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 845-859
-
-
De Leon, D.D.1
Crutchlow, M.F.2
Ham, J.Y.N.3
-
12
-
-
0032908654
-
Glucose-lowering and insulin-sensitizing actions of exendin-4
-
Young AA, Gedulin BR, Bhavsar S, et al. Glucose-lowering and insulin-sensitizing actions of exendin-4. Diabetes 1999; 48: 1026-34
-
(1999)
Diabetes
, vol.48
, pp. 1026-1034
-
-
Young, A.A.1
Gedulin, B.R.2
Bhavsar, S.3
-
13
-
-
0036305993
-
Glucagon-like peptide-1 (GLP-1) and glucose metabolism in human myocytes
-
Luque MA, Gonzalez N, Marquez L, et al. Glucagon-like peptide-1 (GLP-1) and glucose metabolism in human myocytes. J Endocrinol 2002; 173: 465-73
-
(2002)
J Endocrinol
, vol.173
, pp. 465-473
-
-
Luque, M.A.1
Gonzalez, N.2
Marquez, L.3
-
14
-
-
0035980166
-
Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes
-
Vila Petroff MGV, Egan JM, Wang X, et al. Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes. Circ Res 2001; 89: 445-52
-
(2001)
Circ Res
, vol.89
, pp. 445-452
-
-
Vila Petroff, M.G.V.1
Egan, J.M.2
Wang, X.3
-
15
-
-
0028077525
-
Glucagon-like peptide-1 (7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3t3-l1 adipocytes: One of several potential extrapancreatic sites of GLP-1 action
-
Egan JM, Montrose-Rafizadeh C. Wang Y, et al. Glucagon-like peptide-1 (7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3t3-l1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action. Endocrinology 1994; 135: 2070-5
-
(1994)
Endocrinology
, vol.135
, pp. 2070-2075
-
-
Egan, J.M.1
Montrose-Rafizadeh, C.2
Wang, Y.3
-
16
-
-
12144260853
-
Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury
-
Bose AK, Mocanu MM, Carr RD, et al. Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury. Diabetes 2005; 54: 146-51
-
(2005)
Diabetes
, vol.54
, pp. 146-151
-
-
Bose, A.K.1
Mocanu, M.M.2
Carr, R.D.3
-
17
-
-
0038577144
-
Cardiac function in mice lacking the glucagon-like peptide-1 receptor
-
Gros R, You X, Baggio LL, et al. Cardiac function in mice lacking the glucagon-like peptide-1 receptor. Endocrinology 2003; 144: 2242-52
-
(2003)
Endocrinology
, vol.144
, pp. 2242-2252
-
-
Gros, R.1
You, X.2
Baggio, L.L.3
-
19
-
-
33646165752
-
LAF 237: A dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of type 2 diabetes mellitus
-
Cornell S. LAF 237: a dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of type 2 diabetes mellitus. J Pharm Technol 2006; 22: 1-5
-
(2006)
J Pharm Technol
, vol.22
, pp. 1-5
-
-
Cornell, S.1
-
20
-
-
0036307610
-
The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects
-
Hui H, Farilla L, Merkel P, et al. The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects. Eur J Endocrinol. 2002; 146: 863-9
-
(2002)
Eur J Endocrinol
, vol.146
, pp. 863-869
-
-
Hui, H.1
Farilla, L.2
Merkel, P.3
-
21
-
-
28144441354
-
Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy
-
Nikolaidis LA, Elahi D, Shen YT, et al. Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am J Physiol 2005; 289: H2401-8
-
(2005)
Am J Physiol
, vol.289
-
-
Nikolaidis, L.A.1
Elahi, D.2
Shen, Y.T.3
-
22
-
-
4344697195
-
Cardiac metabolism as a target for the treatment of heart failure
-
Taegtmeyer H. Cardiac metabolism as a target for the treatment of heart failure. Circulation 2004; 110: 894-6
-
(2004)
Circulation
, vol.110
, pp. 894-896
-
-
Taegtmeyer, H.1
-
23
-
-
0030583731
-
Interactions of exendin-(9-39) amide and of exendin-4 on arterial blood pressure and heart rate in rats
-
Barragan JM, Rodriguez RE, Eng J, et al. Interactions of exendin-(9-39) amide and of exendin-4 on arterial blood pressure and heart rate in rats. Regul Pept 1996; 67: 63-8
-
(1996)
Regul Pept
, vol.67
, pp. 63-68
-
-
Barragan, J.M.1
Rodriguez, R.E.2
Eng, J.3
-
24
-
-
8544258807
-
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease
-
Nystrom T, Gutniak MK, Zhang Q, et al. Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease. Am J Physiol 2004; 287: E1209-15
-
(2004)
Am J Physiol
, vol.287
-
-
Nystrom, T.1
Gutniak, M.K.2
Zhang, Q.3
-
25
-
-
0842346377
-
Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin
-
Buyukcoskun NI, Gulec G. Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin. Regul Pept 2004; 118: 33-8
-
(2004)
Regul Pept
, vol.118
, pp. 33-38
-
-
Buyukcoskun, N.I.1
Gulec, G.2
-
26
-
-
0028042205
-
Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats
-
Barragan JM, Rodriguez RE, Blazquez E. Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats. Am J Physiol 1994; 266: E459-66
-
(1994)
Am J Physiol
, vol.266
-
-
Barragan, J.M.1
Rodriguez, R.E.2
Blazquez, E.3
-
27
-
-
31144446219
-
Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious rats
-
Gardiner SM, March JE, Kemp PA, et al. Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious rats. J Pharmacol Exp Ther 2006; 316: 852-9
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 852-859
-
-
Gardiner, S.M.1
March, J.E.2
Kemp, P.A.3
-
28
-
-
4344605042
-
Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy
-
Nikolaidis LA, Elahi D, Hentosz T, et al. Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy. Circulation 2004; 110: 955-61
-
(2004)
Circulation
, vol.110
, pp. 955-961
-
-
Nikolaidis, L.A.1
Elahi, D.2
Hentosz, T.3
-
29
-
-
0032714917
-
Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats
-
Barragan JM, Eng J, Rodriguez R, et al. Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats. Am J Physiol 1999; 277: E784-91
-
(1999)
Am J Physiol
, vol.277
-
-
Barragan, J.M.1
Eng, J.2
Rodriguez, R.3
-
30
-
-
0030836364
-
Cardiovascular and pancreatic endocrine responses to glucagon-like peptide-1(7-36) amide in the conscious calf
-
Edwards CMB, Edwards AV, Bloom SR. Cardiovascular and pancreatic endocrine responses to glucagon-like peptide-1(7-36) amide in the conscious calf. Exp Physiol 1997; 82: 709-16
-
(1997)
Exp Physiol
, vol.82
, pp. 709-716
-
-
Edwards, C.M.B.1
Edwards, A.V.2
Bloom, S.R.3
-
31
-
-
33646795007
-
Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts
-
Zhao T, Parkkh P, Bhashyam S, et al. Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J Pharmacol Exp Ther 2006; 317: 1106-13
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 1106-1113
-
-
Zhao, T.1
Parkkh, P.2
Bhashyam, S.3
-
32
-
-
0028900758
-
Tissue-specific expression of the human receptor for glucagon-like peptide-1: Brain, heart and pancreatic forms have the same deduced amino acid sequences
-
Wei Y, Mojsov S. Tissue-specific expression of the human receptor for glucagon-like peptide-1: brain, heart and pancreatic forms have the same deduced amino acid sequences. FEBS Lett 1995; 358: 219-24
-
(1995)
FEBS Lett
, vol.358
, pp. 219-224
-
-
Wei, Y.1
Mojsov, S.2
-
33
-
-
9944251347
-
Glucagon-like peptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism
-
Nystrom T, Gonon AT, Sjoholm A, et al. Glucagon-like peptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism. Regul Pept 2005; 125: 173-7
-
(2005)
Regul Pept
, vol.125
, pp. 173-177
-
-
Nystrom, T.1
Gonon, A.T.2
Sjoholm, A.3
-
34
-
-
0037629509
-
Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium
-
Kavianipour M, Ehlers MR, Malmberg K, et al. Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium. Peptides 2003; 24: 569-78
-
(2003)
Peptides
, vol.24
, pp. 569-578
-
-
Kavianipour, M.1
Ehlers, M.R.2
Malmberg, K.3
-
35
-
-
0032976939
-
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients
-
Toft-Nielsen MB, Madsbad S, Holst JJ. Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. Diabetes Care 22: 1999, 1143
-
(1999)
Diabetes Care
, vol.22
, pp. 1143
-
-
Toft-Nielsen, M.B.1
Madsbad, S.2
Holst, J.J.3
-
36
-
-
34248218497
-
-
Vilsboll T, Zdravkovic M, Le-Thi T, et al. Liraglutide treatment, blood pressure and biomarkers of cardiovascular risk in patients with type 2 diabetes: 14 weeks monotherapy study. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 2007-PO
-
Vilsboll T, Zdravkovic M, Le-Thi T, et al. Liraglutide treatment, blood pressure and biomarkers of cardiovascular risk in patients with type 2 diabetes: 14 weeks monotherapy study. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 2007-PO
-
-
-
-
37
-
-
33644682164
-
Initial experience with GLP-1 treatment on metabolic control and myocardial function in patients with type 2 diabetes mellitus and heart failure
-
Thrainsdottir I, Malmberg K, Olsson A, et al. Initial experience with GLP-1 treatment on metabolic control and myocardial function in patients with type 2 diabetes mellitus and heart failure. Diab Vasc Res 2004; 1: 40-3
-
(2004)
Diab Vasc Res
, vol.1
, pp. 40-43
-
-
Thrainsdottir, I.1
Malmberg, K.2
Olsson, A.3
-
38
-
-
34248178419
-
-
Kapitza C, Heise T, Klein O, et al. BIM51077, a novel GLP-1 analog, achieves sustained improvement in blood glucose control over 28 days of treatment. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 500-P
-
Kapitza C, Heise T, Klein O, et al. BIM51077, a novel GLP-1 analog, achieves sustained improvement in blood glucose control over 28 days of treatment. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 500-P
-
-
-
-
39
-
-
34248184979
-
-
Thibaudeau K, Robitaille M, Wen S, et al. CJC-1134-PC: An exendin-4 conjugate with extended pharmacodynamic profiles in rodents. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 434-P
-
Thibaudeau K, Robitaille M, Wen S, et al. CJC-1134-PC: An exendin-4 conjugate with extended pharmacodynamic profiles in rodents. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 434-P
-
-
-
-
40
-
-
34248220993
-
-
Baggio LL, Huang Q, Drucker DJ. The long-acting albumin-exendin-4 GLP-1R agonist CJC-1134 engages central and peripheral mechanisms regulating glucose homeostasis. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 362-OR
-
Baggio LL, Huang Q, Drucker DJ. The long-acting albumin-exendin-4 GLP-1R agonist CJC-1134 engages central and peripheral mechanisms regulating glucose homeostasis. In: Program and abstracts of the American Diabetes Association 66th Scientific Sessions; 2006 June 9-13; Washington (DC). Diabetes 2006; 55 Suppl. 1: 362-OR
-
-
-
-
41
-
-
0035892681
-
Vasorelaxant effect of glucagon-like peptide-(7-36) amide and amylin on the pulmonary circulation of the rat
-
Golpon HA, Puechner A, Welte T, et al. Vasorelaxant effect of glucagon-like peptide-(7-36) amide and amylin on the pulmonary circulation of the rat. Regulatory Peptides 2001; 102: 81-6
-
(2001)
Regulatory Peptides
, vol.102
, pp. 81-86
-
-
Golpon, H.A.1
Puechner, A.2
Welte, T.3
|