Radiosynthesis of [18F] N-(3-Fluoropropyl)-2-β- Carbomethoxy-3-β-(4-Bromophenyl) Nortropane and the regional brain uptake in non human primate using PET

Nuclear Medicine and Biology

Volumn 31, Issue 1, 2004, Pages 125-131

  Chaly, Thomas ^a   Baldwin, R M ^b   Neumeyer, John L ^c   Hellman, Matthew J ^a   Dhawan, Vijay ^a   Garg, Pradeep K ^b   Tamagnan, Gilles ^b   Staley, Julie K ^b   Al Tikriti, Mohammed S ^b   Hou, Yankun ^b   Zoghbi, Sami S ^b   Gu, Xiao Hui ^c   Zong, R ^c   Eidelberg, David ^a  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MCLEAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE TRANSPORTER; DRUG METABOLITE; N (3 FLUOROPROPYL) 2BETA CARBOMETHOXY 3BETA (4 BROMOPHENYL)NORTROPANE F 18; NORTROPANE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; CARRIER PROTEIN; DIAGNOSTIC AGENT; MEMBRANE PROTEIN; N (3 FLUOROPROPYL) 2 CARBOMETHOXY 3 (4 BROMOPHENYL)NORTROPANE; N-(3-FLUOROPROPYL)-2-CARBOMETHOXY-3-(4-BROMOPHENYL)NORTROPANE; NERVE PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED STUDY; CORPUS STRIATUM; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG PURIFICATION; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; IN VIVO STUDY; LIPOPHILICITY; METHODOLOGY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIMATE; TIME; ANIMAL; BLOOD; CHEMISTRY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; ISOTOPE LABELING; METABOLIC CLEARANCE RATE; METABOLISM; PAPIO; SCINTISCANNING; SYNTHESIS; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; ISOTOPE LABELING; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METABOLIC CLEARANCE RATE; NERVE TISSUE PROTEINS; NORTROPANES; PAPIO; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 1642533550     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(03)00110-0     Document Type: Article

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