Case report: An unusual cause of elevated serum total βhCG

Annals of Clinical and Laboratory Science

Volumn 37, Issue 2, 2007, Pages 186-191

  Buckner, Carl L ^a   Wilson, Lisa ^a   Papadea, Christine N ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

hCG; Hemodialysis; Heterophile antibodies; Immunoassays; Pituitary hormones

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; HETEROPHILE ANTIBODY; BIOLOGICAL MARKER;

ADULT; ARTICLE; CASE REPORT; CHRONIC KIDNEY FAILURE; DIFFERENTIAL DIAGNOSIS; FEMALE; HORMONE BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; HYDROSALPINX; KIDNEY CLEARANCE; LABORATORY TEST; PREGNANCY; PRIORITY JOURNAL; SALPINGECTOMY; URINALYSIS; UTERUS SURGERY; BLOOD; LABORATORY DIAGNOSIS; METHODOLOGY; SEROLOGY; URINE;

ADULT; BIOLOGICAL MARKERS; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; SEROLOGIC TESTS;

EID: 34248175012     PISSN: 00917370     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Bower B, Moore R, Schwartz M. Endocrine function and carbohydrates, tumor markers. In: Clinical Laboratory Medicine, 2nd ed (McClatchey K, Ed), Lippincott Williams and Wilkins, Philadelphia, 2002; pp 329-330, 491.
2. Cole LA, Sutton JM, Higgins TN, Cembrowski GS. Between-method variation in human chorionic gonadotropin test results. Clin Chem 2004;50:874-882.
3. Klee GG. Interferences in hormone immunoassays. Clin Lab Med 2004;24:1-18.
4. Cole LA, Khanlian SA. Inappropriate management of women with persistent low hCG results. J Reprod Med 2004;49:423-432.
5. Rotmensch S, Cole LA. False diagnosis and needless therapy of presumed malignant disease in women with false-positive human chorionic gonadotropin concentrations. Lancet 2000;355:712-715.
6. Butler SA, Cole LA. Use of heterophilic blocking agent (HBT) in reducing false-positive hCG results. Clin Chem 2001;47:1332-1333.
7. Ismail AAA, Walker PL, Barth JH, Lewandowski KC, Jones R, Burr, WA. Wrong biochemistry results: Two case reports and observational study in 5310 patients on potentially misleading thyroid-stimulating hormone and gonadotropin immunoassay results. Clin Chem 2002;48:2023-2029.
8. Schwarz A, Post KG, Keller F, Molzahn M. Value of human chorionic gonadotropin measurements in blood as a pregnancy test in women on maintenance hemodialysis. Nephron 1985;39:341-343.
9. Hoermann R, Spoettl G, Moncayo R, Mann K. Evidence for the presence of human chorionic gonadotropin (hCG) and free β-subunit of hCG in the human pituitary. J Clin Endocrinol Metab 1990;71:179-186.
10. Pimstone B, Epstein S, Hamilton SM, LeRoith D, Hendricks S. Metabolic clearance and plasma half disappearance time of exogenous gonadotropin releasing hormone in normal subjects and in patients with liver disease and chronic renal failure. J Clin Endocrinol Metab 1977;44:356-360.
11. Sievertsen GD, Lim VS, Nakawatase C, Frohman LA. Metabolic clearance and secretion rates of human prolactin in normal subjects and in patients with chronic renal failure. J Clin Endocrinol Metab 1980;50:846-852.
12. Lim VS, Kathpalia SC, Frohman LA. Hyperprolactinemia and impaired pituitary response to suppression and stimulation in chronic renal failure: reversal after transplantation. J Clin Endocrinol Metab 1979;48:101-107.
13. Ramirez G, O'Neill WM Jr, Bloomer HA, Jubiz W. Abnormalities in the regulation of prolactin in patients with chronic renal failure. J Clin Endocrinol Metab 1977;45:658-661.
14. Coresh J, Byrd-Holt D, Astor BC, Briggs JP, Eggers PW, Lacher DA, Hostetter TH. Chronic kidney disease awareness, prevalence, and trends among U.S. adults, 1999 to 2000. J Am Soc Nephi 2005;16:180-188.