The value of comparative genomics in understanding mycobacterial virulence: Mycobacterium tuberculosis H37Ra genome sequencing - A worthwhile endeavour

Journal of Biosciences

Volumn 32, Issue 2, 2007, Pages 185-189

  Sharma, Deepak ^a,b   Tyagi, Jaya Sivaswami ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

Genomics; Mycobacterium tuberculosis H37Ra; Virulence

Indexed keywords

BCG VACCINE;

ATTENUATION; BACTERIAL GENETICS; BACTERIAL VIRULENCE; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENOMICS; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOREACTIVITY; MEDICAL RESEARCH; MICROARRAY ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; NECROSIS; NONHUMAN; NOTE; PATHOGENESIS; RNA HYBRIDIZATION; TREATMENT FAILURE; TUBERCULOSIS;

GENOME, BACTERIAL; GENOMICS; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; VIRULENCE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 34248139554     PISSN: 02505991     EISSN: 02505991     Source Type: Journal    
DOI: 10.1007/s12038-007-0018-z     Document Type: Note

References (28)

1. Behr M A, Wilson M A, Gill W P, Salamon H, Schoolnik G K, Rane S and Small P M 1999 Comparative genomics of BCG vaccines by whole-genome DNA microarray; Science 284 1520-1523
2. Bifani P, Moghazeh S, Shopsin B, Driscoll J, Ravikovitch A and Kreiswirth B N 2000 Molecular characterization of Mycobacterium tuberculosis H37Rv/Ra variants: distinguishing the mycobacterial laboratory strain; J. Clin. Microbiol. 38 3200-3204
3. Bishai W R, Dannenberg A M Jr, Parrish N, Ruiz R, Chen P, Zook B C, Johnson W, Boles J W and Pitt M L 1999 Virulence of Mycobacterium tuberculosis CDC1551 and H37Rv in rabbits evaluated by Lurie's pulmonary tubercle count method; Infect. Immun. 67 4931-4934
4. Brosch R, Philipp W J, Stavropoulos E, Colston M J, Cole S T and Gordon S V 1999 Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain; Infect. Immun. 67 5768-5774
5. Cardona P J, Soto C Y, Martin C, Giquel B, Agusti G, Andreu N, Guirado E, Sirakova T, Kolattukudy P, Julian E and Luquin M 2006 Neutral-red reaction is related to virulence and cell wall methyl-branched lipids in Mycobacterium tuberculosis; Microbes Infect. 8 183-190
6. Chen M, Gan H and Remold H G 2006 A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis; J. Immunol. 176 3707-3716
7. Cole S T, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon S V, Eiglmeier K et al 1998 Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence; Nature (London) 393 537-544
8. Cole S T, Eiglmeier K, Parkhill J, James K D, Thomson N R, Wheeler P R, Honore N, Garnier T et al 2001 Massive gene decay in the leprosy bacillus; Nature (London) 409 1007-1011
9. Corbett E L, Watt C J, Walker N, Maher D, Williams B G, Raviglione M C and Dye C 2003 The growing burden of tuberculosis: global trends and interactions with the HIV epidemic; Arch. Int. Med. 163 1009-1021
10. Dasgupta N, Kapur V, Singh K K, Das T K, Sachdeva S, Jyothisri K and Tyagi J S 2000 Characterization of a two-component system, devR-devS, of Mycobacterium tuberculosis; Tuber. Lung Dis. 80 141-159
11. Fleischmann R D, Alland D, Eisen J A, Carpenter L, White O, Peterson J, DeBoy R, Dodson R, et al 2002 Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains; J. Bacteriol. 184 5479-5490
12. Gao Q, Kripke K, Arinc Z, Voskuil M and Small P 2004 Comparative expression studies of a complex phenotype: cord formation in Mycobacterium tuberculosis; Tuberculosis (Edinb) 84 188-196
13. Garnier T, Eiglmeier K, Camus J C, Medina N, Mansoor H, Pryor M, Duthoy S Grondin S et al 2003 The complete genome sequence of Mycobacterium bovis; Proc. Natl. Acad. Sci. USA 100 7877-7882
14. He X Y, Zhuang Y H, Zhang X G and Li G L 2003 Comparative proteome analysis of culture supernatant proteins of Mycobacterium tuberculosis H37Rv and H37Ra; Microbes Infect. 5 851-856
15. Kinger A K and Tyagi J S 1993 Identification and cloning of genes differentially expressed in the virulent strain of Mycobacterium tuberculosis; Gene 131 113-117
16. Lewis K N, Liao R, Guinn K M, Hickey M J, Smith S, Behr M A and Sherman D R 2003 Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation; J. Infect. Dis. 187 117-123
17. Malhotra V, Sharma D, Ramanathan V D, Shakila H, Saini D K, Chakravorty S, Das T K, Li Q, Silver R F, Narayanan P R and Tyagi J S 2004 Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis; FEMS Microbiol. Lett. 231 237-245
18. Middlebrook G, Dubos R J and Pierce C 1947 Virulence and morphological characteristics of mammalian tubercle bacilli; J. Exp. Med. 86 175-184
19. Mostowy S, Cleto C, Sherman D R and Behr M A 2004 The Mycobacterium tuberculosis complex transcriptome of attenuation; Tuberculosis (Edinb) 84 197-204
20. Parish T, Smith D A, Kendall S, Casali N, Bancroft G J and Stoker N G 2003 Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis; Infect. Immun. 71 1134-1140
21. Park H D, Guinn K M, Harrell M I, Liao R, Voskuil M I, Tompa M, Schoolnik G K and Sherman D R 2003 Rv313-3c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis; Mol. Microbiol. 48 833-843
22. Pym A S, Brodin P, Brosch R, Huerre M and Cole S T 2002 Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti; Mol. Microbiol. 46 709-717
23. Ramakrishnan T and Chandrasekhar P 1999 The control of tuberculosis: a continuous game of snakes and ladders; J. Biosci. 24 143-152
24. Rindi L, Lari N and Garzelli C 1999 Search for genes potentially involved in Mycobacterium tuberculosis virulence by mRNA differential display; Biochem. Biophys. Res. Commun. 258 94-101
25. Silver R F, Li Q and Ellner J J 1998 Expression of virulence of Mycobacterium tuberculosis within human monocytes: virulence correlates with intracellular growth and induction of tumor necrosis factor alpha but not with evasion of lymphocyte-dependent monocyte effector functions; Infect. Immun. 66 1190-1199
26. Tyagi J S and Sharma D 2004 Signal transduction systems of mycobacteria with special reference to M. tuberculosis; Curr. Sci. 86 93-102
27. Voskuil M I, Schnappinger D, Visconti K C, Harrell M I, Dolganov G M, Sherman D R and Schoolnik G K 2003 Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program; J. Exp. Med. 198 705-713
28. Wayne L G and Sohaskey C D 2001 Nonreplicating persistence of Mycobacterium tuberculosis; Annu. Rev. Microbiol. 55 139-163