Considerations of pharmacology on fitness for duty in the operational environment

Aviation Space and Environmental Medicine

Volumn 78, Issue 5 II, 2007, Pages

  Kautz, Mary A ^d   Thomas, Maria L ^a,b   Caldwell, J Lynn ^c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b U S ARMY AEROMEDICAL RESEARCH LABORATORY   (United States)

^c AIR FORCE RESEARCH LABORATORY   (United States)

^d NONE   (United States)

Author keywords

Cognitive performance; Fatigue countermeasures; Military operations; Pharmaceuticals; Pharmacology countermeasures; Psychotropic

Indexed keywords

ARMODAFINIL; BOTULINUM TOXIN A; CAFFEINE; DEXAMPHETAMINE; MODAFINIL; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TEMAZEPAM; ZALEPLON; ZOLPIDEM;

AIRPLANE CREW; CLINICAL TRIAL; DEPRESSION; ENVIRONMENT; FATIGUE; FITNESS; HUMAN; MIGRAINE; NEUROPSYCHOLOGICAL TEST; PERFORMANCE; PREMENSTRUAL DYSPHORIC DISORDER; REVIEW; SLEEP DISORDER;

COGNITION; CONGRESSES; FATIGUE; HUMANS; MILITARY MEDICINE; MILITARY PERSONNEL; OPERATIONS RESEARCH; PSYCHOTROPIC DRUGS; TASK PERFORMANCE AND ANALYSIS;

EID: 34248139061     PISSN: 00956562     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Beaumont M, Batejat D, Coste O, et al. Recovery after prolonged sleep deprivation: residual effects of slow-release caffeine on recovery sleep, sleepiness and cognitive functions. Neuropsychobiology 2005; 51:16-27.
2. Beaumont M, Batejat D, Van Beers P, et al. Pharmacological strategies to maintain cognitive performance and wakefulness during military operations. J Sleep Res 2006; 15(1, Suppl.):194.
3. Bonnet MH, Balkin TJ, Dinges DF, et al. The use of stimulants to modify performance during sleep loss: a review by the Sleep Deprivation and Stimulant Task Force of the American Academy of Sleep Medicine. Sleep 2005; 28:1163-87.
4. Boyle J, Mansbach H, Nicholson AN. Evaluation of the central effects of CX717 during extended wakefulness [Abstract]. Sleep 2006; 29(Suppl.):A44.
5. Caldwell JA, Caldwell JL. An in-flight investigation of the efficacy of dextroamphetamine for sustaining helicopter pilot performance. Aviat Space Environ Med 1997; 68:1073-80.
6. Caldwell JA, Caldwell JL. Fatigue in military aviation: an overview of U.S. military-approved pharmacological countermeasures. Aviat Space Environ Med 2005; 76(7, Suppl.): C39-51.
7. Caldwell JA, Caldwell JL, Crowley JS, Jones HD. Sustaining helicopter pilot performance with dexadrine during periods of sleep deprivation. Aviat Space Environ Med 1995; 66:930-7.
8. Caldwell JA, Caldwell JL, Smythe NK, Hall KK. A double-blind, placebo-controlled investigation of the efficacy of modafinil for sustain the alertness and performance of aviators: a helicopter simulator study. Psychopharmacology (Berl) 2000; 150:272-82.
9. Corona BM, Fiedler E. Potential paradigm for assessments of biomedical technologies in the operational environment. Aviat Space Environ Med 2007; 78(5, Suppl.):B245-51.
10. Dinges DF, Arora S, Darwish M, Niebler GE. Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss. Curr Med Res Opin 2006; 22:159-67.
11. Doan BK, Caldwell JA, Hursh SR, et al. Assessing psychoactive pharmaceuticals and transitioning pharmacological fatigue countermeasures into operational environments. Aviat Space Environ Med 2005; 76(7, Suppl.):C34-38.
12. Gottselig JM, Adam M, Retey JV, et al. Random number generation during sleep deprivation: effects of caffeine on response maintenance and stereotypy. J Sleep Res 2006; 15:31-40.
13. Haskell CF, Kennedy DO, Wesnes KA, Scholey AB. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine. Psychopharmacology (Berl) 2005; 179:813-25.
14. Huck NO, Kendall AP, McBride SA, Killgore WD. The perception of facial emotion is enhanced by psychostimulants following two nights of sleep deprivation [Abstract]. Sleep 2006; 29(Suppl.):A136.
15. Jaeger HF. A glance at the tip of a big iceberg: commentary on "recommendations for the ethical use of pharmacological fatigue countermeasures in the U.S. military". Aviat Space Environ Med 2007; 78(5, Suppl.):B128-30.
16. Kahn-Green ET, Day LM, Conrad AK, et al. Short-term vs. long-term planning abilities: differential effects of stimulants on executive function in sleep deprived individuals [Abstract]. Sleep 2006; 29(Suppl.):A370.
17. Kamimori G, Fletcher A, Johnson D, et al. Ability of caffeine to maintain night-time performance during three consecutive nights without sleep [Abstract]. Sleep 2006; 29(Suppl.):A117.
18. Killgore WD, Killgore DB, Kahn-Green ET, et al. Introversive personalities are more resilient against sleep loss [Abstract]. Sleep 2006; 29(Suppl.):A137.
19. Killgore WS, McBride SA, Killgore DB, Balkin TJ. The effects of caffeine, dextroamphetamine and modafinil on humor appreciation during sleep deprivation. Sleep 2006; 29:841-7.
20. Kratz K, Anderson S, Poppen B. Premenstrual dysphoric disorder: treatment with sertraline, neuropsychological effects, and flight status. Aviat Space Environ Med 2007; 78(5, Suppl.): B138-43.
21. McGechan A, Wellington K. Ramelteon. CNS Drugs 2005; 19: 1057-65.
22. Meijer M. A human performance perspective on the ethical use of cogniceuticals: commentary on "recommendations for the ethical use of pharmacological fatigue countermeasures in the U.S. military". Aviat Space Environ Med 2007; 78(5, Suppl.):B131-3.
23. Muckle AE, Killgore DB, Killgore WD. Gender differences in the effects of stimulant medications on the ability to estimate unknown quantities when sleep deprived [Abstract]. Sleep, 2006; 29(Suppl.):A369.
24. Murray CJ, Killgore DB, Kamimori GH, Killgore WD. Individual differences in stress management capacity predict responsiveness to caffeine during sleep deprivation [Abstract]. Sleep 2006; 29(Suppl.):A43.
25. Nielsen JN. Danish perspective: commentary on "recommendations for the ethical use of pharmacological fatigue countermeasures in the U.S. military." Aviat Space Environ Med 2007; 78(5, Suppl.):B134-5.
26. Richards JM, Killgore WD. The effect of caffeine, dextroamphetamine, and modafinil on alertness and mood during sleep deprivation [Abstract]. Sleep 2006; 29(Suppl.):A43.
27. Roedig E. German perspective: commentary on "recommendations for the ethical use of pharmacological fatigue countermeasures in the U.S. military." Aviat Space Environ Med 2007; 78(5, Suppl.):B136-7.
28. Roth T, Stubbs C, Walsh, JK. Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment. Sleep 2005; 28:303-7.
29. Russo M. Potential flight performance-related effects of SSRI use [Abstract]. Aviat Space Environ Med 2004; 75:B66.
30. Russo MB. Recommendations for the ethical use of pharmacologic fatigue countermeasures in the U.S. military. An engagement in the battle over the use of cognitive enhancement technologies in war. Aviat Space Environ Med 2007; 78(5, Suppl.):XXX-xx.
31. Vo A, Satori R, Jabbari B, et al. Botulinum toxin type-A in the prevention of migraine: a double-blind controlled trial. Aviat Space Environ Med 2007; 78(5, Suppl.):XXX-xx..
32. Walsh JK, Randazzo AC, Stone KL, Schweitzer PK. Modafinil improves alertness, vigilance, and executive function during simulated night shifts. Sleep 2004; 27:434-9.
33. Wesensten NJ. Effects of modafinil on cognitive performance and alertness during sleep deprivation. Curr Pharm Des 2006; 12: 2457-71.
34. Wesensten NJ, Killgore WDS, Balkin TJ. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation. J Sleep Res 2005; 14:255-66.