Morphological observation and in vitro angiogenesis assay of endothelial cells isolated from human cerebral cavernous malformations

Stroke

Volumn 38, Issue 4, 2007, Pages 1313-1319

  Zhao, Yao ^a   Tan, Yu Zhen ^b   Zhou, Liang Fu ^a   Wang, Hai Jie ^b   Mao, Ying ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Angiogenesis; Cavernous malformations; Endothelial cells

Indexed keywords

COLLAGEN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ADOLESCENT; ADULT; ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; BLOOD CLOTTING; BRAIN TISSUE; CAVERNOUS SINUS THROMBOSIS; CELL CULTURE; CELL ISOLATION; CELL NUCLEUS; CELL STRUCTURE; CHILD; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOLOGY; ELECTRON MICROSCOPE; ENDOTHELIUM CELL; FEMALE; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUBE; WESTERN BLOTTING; BIOASSAY; BRAIN HEMANGIOMA; CELL SEPARATION; CULTURE TECHNIQUE; ELECTRON MICROSCOPY; FLOW CYTOMETRY; METABOLISM; METHODOLOGY; NEOVASCULARIZATION (PATHOLOGY); ORGAN CULTURE TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ADULT; BIOLOGICAL ASSAY; CELL CULTURE TECHNIQUES; CELL NUCLEUS; CELL SEPARATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COLLAGEN; ENDOTHELIAL CELLS; FEMALE; FLOW CYTOMETRY; HEMANGIOMA, CAVERNOUS, CENTRAL NERVOUS SYSTEM; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON; NEOVASCULARIZATION, PATHOLOGIC; ORGAN CULTURE TECHNIQUES; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 34247887668     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000259914.21997.89     Document Type: Article

References (28)

1. Moriarity JL, Clatterbuck RE, Rigamonti D. The natural history of cavernous malformations. Neurosurg Clin North Am. 1999;10:411-417.
2. Bertalanffy H, Benes L, Miyazawa T, Alberti O, Siegel AM, Sure U. Cerebral cavernomas in the adult. Review of the literature and analysis of 72 surgically treated patients. Neurosurg Rev. 2002;25:1-53.
3. Little JR, Awad IA, Jones SC, Ebrahim ZY. Vascular pressures and cortical blood flow in cavernous angioma of the brain. J Neurosurg. 1990;73:555-559.
4. Marini V, Ferrera L, Dorcaratto A, Viale G, Origone P, Mareni C, Garre C. Identification of a novel krit1 mutation in an italian family with cerebral cavernous malformation by the protein truncation test. J Neurol Sci. 2003;212:75-78.
5. Robinson JR Jr, Awad IA, Zhou P, Barna BP, Estes ML. Expression of basement membrane and endothelial cell adhesion molecules in vascular malformations of the brain: Preliminary observations and working hypothesis. Neurol Res. 1995;17:49-58.
6. Gunel M, Awad IA, Finberg K, Anson JA, Steinberg GK, Batjer HH, Kopitnik TA, Morrison L, Giannotta SL, Nelson-Williams C, Lifton RP. A founder mutation as a cause of cerebral cavernous malformation in Hispanic Americans. N Engl J Med. 1996;334:946-951.
7. Craig HD, Gunel M, Cepeda O, Johnson EW, Ptacek L, Steinberg GK, Ogilvy CS, Berg MJ, Crawford SC, Scott RM, Steichen-Gersdorf E, Sabroe R, Kennedy CT, Mettler G, Beis MJ, Fryer A, Awad IA, Lifton RP. Multilocus linkage identifies two new loci for a mendelian form of stroke, cerebral cavernous malformation, at 7p15-13 and 3q25.2-27. Hum Mol Genet. 1998;7:1851-1858.
8. Sure U, Butz N, Schlegel J, Siegel AM, Wakat JP, Mennel HD, Bien S, Bertalanffy H. Endothelial proliferation, neoangiogenesis, and potential de novo generation of cerebrovascular malformations. J Neurosurg. 2001;94:972-977.
9. Rusnati M, Presta M. Extracellular angiogenic growth factor interactions: an angiogenesis interactome survey. Endothelium. 2006;13:93-111.
10. Presta M, Dell'Era P, Mitola S, Moroni E, Ronca R, Rusnati M. Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev. 2005;16:159-178.
11. Uranishi R, Baev NI, Ng PY, Kim JH, Awad IA. Expression of endothelial cell angiogenesis receptors in human cerebrovascular malformations. Neurosurgery. 2001;48:359-367.
12. Baev NI, Awad IA. Endothelial cell culture from human cerebral cavernous malformations. Stroke. 1998;29:2426-2434.
13. Kanda S, Tomasini-Johansson B, Klint P, Dixelius J, Rubin K, Claesson-Welsh L. Signaling via fibroblast growth factor receptor-1 is dependent on extracellular matrix in capillary endothelial cell differentiation. Exp Cell Res. 1999;248:203-213.
14. Vinters HV, Reave S, Costello P, Girvin JP, Moore SA. Isolation and culture of cells derived from human cerebral microvessels. Cell Tissue Res. 1987;249:657-667.
15. Tan Y. Basic fibroblast growth factor-mediated lymphangiogenesis of lymphatic endothelial cells isolated from dog thoracic ducts: Effects of heparin. Jpn J Physiol. 1998;48:133-141.
16. Maraire JN, Awad IA. Intracranial cavernous malformations: Lesion behavior and management strategies. Neurosurgery. 1995;37:591-605.
17. Kallmann BA, Wagner S, Hummel V, Buttmann M, Bayas A, Tonn JC, Rieckmann P. Characteristic gene expression profile of primary human cerebral endothelial cells. FASEB J. 2002;16:589-591.
18. Muller AM, Hermanns MI, Skrzynski C, Nesslinger M, Muller KM, Kirkpatrick CJ. Expression of the endothelial markers PECAM-1, vWf, and CD34 in vivo and in vitro. Exp Mol Pathol. 2002;72:221-229.
19. Buser R, Montesano R, Garcia I, Dupraz P, Pepper MS. Bovine microvascular endothelial cells immortalized with human telomerase. J Cell Biochem. 2006;98:267-286.
20. Schmaier AH, Kuo A, Lundberg D, Murray S, Cines DB. The expression of high molecular weight kininogen on human umbilical vein endothelial cells. J Biol Chem. 1988;263:16327-16333.
21. Gault J, Sarin H, Awadallah NA, Shenkar R, Awad IA. Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance. Neurosurgery. 2004;55:1-16.
22. Konya D, Yildirim O, Kurtkaya O, Kilic K, Black PM, Pamir MN, Kilic T. Testing the angiogenic potential of cerebrovascular malformations by use of a rat cornea model: usefulness and novel assessment of changes over time. Neurosurgery. 2005;56:1339-1345.
23. Koolwijk P, van Erck MG, de Vree WJ, Vermeer MA, Weich HA, Hanemaaijer R, van Hinsbergh VW. Cooperative effect of TNFalpha, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix: role of urokinase activity. J Cell Biol. 1996;132:1177-1188.
24. Wang F, Van Brocklyn JR, Hobson JP, Movafagh S, Zukowska-Grojec Z, Milstien S, Spiegel S. Sphingosine 1-phosphate stimulates cell migration through a g(i)-coupled cell surface receptor: potential involvement in angiogenesis. J Biol Chem. 1999;274:35343-35350.
25. Zhang C, Harder DR. Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid. Stroke. 2002;33:2957-2964.
26. Koolwijk P, Peters E, van der Vecht B, Hornig C, Weich HA, Alitalo K, Hicklin DJ, Wu Y, Witte L, van Hinsbergh VW. Involvement of VEGFR-2 (KDR/Flk-1) but not VEGFR-1 (Flt-1) in VEGF-a and VEGFc-induced tube formation by human microvascular endothelial cells in fibrin matrices in vitro. Angiogenesis. 2001;4:53-60.
27. Kilic T, Pamir MN, Kullu S, Eren F, Ozek MM, Black PM. Expression of structural proteins and angiogenic factors in cerebrovascular anomalies. Neurosurgery. 2000;46:1179-1191.
28. Kliche S, Waltenberger J. VEGF receptor signaling and endothelial function. IUBMB Life. 2001;52:61-66.