Analysis of pharmacological effect and molecular mechanisms of a traditional herbal medicine by global gene expression analysis: An exploratory study

Journal of Clinical Pharmacy and Therapeutics

Volumn 32, Issue 3, 2007, Pages 247-252

  Hayasaki, T ^a   Sakurai, M ^a   Hayashi, T ^b   Murakami, K ^b   Hanawa, T ^a  

^a KITASATO UNIVERSITY   (Japan)

^b Foundation for Advancement of International Science   (Japan)

Author keywords

DNA chip; Gene expression; Kososan; Traditional herbal medicine

Indexed keywords

CAFFEIC ACID; GLYCYRRHIZIC ACID; HERBACEOUS AGENT; HESPERIDIN; KOSOSAN; LIQUIRITIGENIN; LIQUIRITIN; ROSMARINIC ACID; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; DNA MICROARRAY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; FEMALE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERVIEW; MALE; NORMAL HUMAN; THREE DIMENSIONAL IMAGING;

ADULT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MALE; MEDICINE, KAMPO; MIDDLE AGED; MOLECULAR STRUCTURE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PILOT PROJECTS; TIME FACTORS;

EID: 34247877617     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2007.00818.x     Document Type: Article

References (8)

1. Kiyohara H, Matsumoto T, Yamada H (2004) Combination effects of herbs in a multi-herbal formula: expression of Juzen-taiho-to's immuno-modulatory activity on the intestinal immune system. Evidence-based Complementary and Alternative Medicine, 1, 83 91.
2. Luo L, Sarunga RC, Guo H et al. (1999) Gene expression profiles of laser-captured adjacent neuronal subtypes. Nature Medicine, 5, 117 122.
3. Hughes T, Mao M, Jones AR et al. (2001) Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer. Nature Biotechnology, 19, 342 347.
4. Zhou A, Hassel BA, Silverman RH (1993) Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action. Cell, 5, 753 765.
5. Solias A, Cossu P, Poddighe P, Tocco A, Deplano A, Garrucciu G, Diana MS (1993) Changes of serum 2′,5′-oligoadenylate synthetase activity during interferon treatment of chronic hepatitis C. Liver, 13, 253 258.
6. Rubin BB, Downey GP, Koh A et al. (2005) Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity. The Journal of Biological Chemistry, 280, 7519 7529.
7. Nassenstein C, Braun A, Erpenbeck VJ et al. (2003) The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma. The Journal of Experimental Medicine, 198, 455 467.
8. Shiratsuchi T, Oda K, Nishimori H, Suzuki M, Takahashi E, Tokino T, Nakamura Y (1998) Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. Biochemical and Biophysical Research Communications, 251, 158 165.