Lack of association of the cyclooxygenase-2 and inducible nitric oxide synthase gene polymorphism with risk of cervical cancer in korean population

Annals of the New York Academy of Sciences

Volumn 1095, Issue , 2007, Pages 134-142

  Taek, Sang Lee ^a,b   Yong, Tark Jeon ^b   Jae, Weon Kim ^b   Noh, Hyun Park ^b   Soon, Beom Kang ^b   Hyo, Pyo Lee ^b   Yong, Sang Song ^b  

^a Seoul National University Boramae Hospital   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Cyclooxygenase 2; Nitric oxide synthase; Polymorphism

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 5; INDUCIBLE NITRIC OXIDE SYNTHASE; LEUCINE; PROSTAGLANDIN SYNTHASE; SERINE; UNCLASSIFIED DRUG;

ADULT; CANCER INVASION; CANCER RISK; CANCER STAGING; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA POLYMORPHISM; EXON; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HISTOLOGY; HUMAN; INFLAMMATION; KOREA; LYMPH NODE; MAJOR CLINICAL STUDY; PROTEIN DOMAIN; SINGLE NUCLEOTIDE POLYMORPHISM; UNTRANSLATED REGION; UTERINE CERVIX CANCER; ARTICLE; CASE CONTROL STUDY; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; UTERINE CERVIX TUMOR;

CASE-CONTROL STUDIES; CYCLOOXYGENASE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KOREA; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; POLYMORPHISM, SINGLE NUCLEOTIDE; UTERINE CERVICAL NEOPLASMS;

EID: 34247868840     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1397.017     Document Type: Conference Paper

References (29)

1. COUSSENS, L.M. & Z. WERB. 2002. Inflammation and cancer. Nature 420: 860-867.
2. AMES, B.N., M.K. SHIGENAGA & T.M. HAGEN. 1993. Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA 90: 7915-7922.
3. SKAPINYECZ, J., et al. 2003. Pelvic inflammatory disease is a risk factor for cervical cancer. Eur. J. Gynaecol. Oncol. 24: 401-404.
4. SMITH, J.S., et al. 2002. Evidence for Chlamydia trachomatis as a human papillomavirus cofactor in the etiology of invasive cervical cancer in Brazil and the Philippines. J. Infect. Dis. 185: 324-331.
5. HAWES, S.E. & N.B. KIVIAT. 2002. Are genital infections and inflammation cofactors in the pathogenesis of invasive cervical cancer? J. Natl. Cancer Inst. 94: 1592-1593.
6. SIMON, L.S. 1999. Role and regulation of cyclooxygenase-2 during inflammation. Am. J. Med. 106: 37S-42S.
7. KHURI, F.R., et al. 2001. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin. Cancer Res. 7: 861-867.
8. WILLIAMS, C.S., M. MANN & R.N. DUBOIS. 1999. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 18: 7908-7916.
9. FERRANDINA, G., et al. 2004. Prognostic role of the ratio between cyclooxygenase-2 in tumor and stroma compartments in cervical cancer. Clin. Cancer Res. 10: 3117-3123.
10. SHIRAHAMA, T. & C. SAKAKURA. 2001. Overexpression of cyclooxygenase-2 in squamous cell carcinoma of the urinary bladder. Clin. Cancer Res. 7: 558-561.
11. VALLANCE, P. & J. COLLIER. 1994. Biology and clinical relevance of nitric oxide. BMJ 309: 453-457.
12. LALA, P.K. & C. CHAKRABORTY. 2001. Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol. 2: 149-156.
13. PARK, S.W., et al. 2003. The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines. Int. J. Cancer 107: 729-738.
14. CHEN, H.H., et al. 2005. Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 63: 1093-1100.
15. KIM, M.H., et al. 2003. Expression of cyclooxygenase-1 and -2 associated with expression of VEGF in primary cervical cancer and at metastatic lymph nodes. Gynecol. Oncol. 90: 83-90.
16. RYU, H.S., et al. 2000. High cyclooxygenase-2 expression in stage IB cervical cancer with lymph node metastasis or parametrial invasion. Gynecol. Oncol. 76: 320-325.
17. HALUSHKA, M.K., et al. 1999. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat. Genet. 22: 239-247.
18. COX, D., C. BOILLOT & F. CANZIAN. 2001. Data mining: efficiency of using sequence databases for polymorphism discovery. Hum. Mutat. 17: 141-150.
19. PAPAFILI, A., et al. 2002. Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arterioscler. Thromb. Vasc. Biol. 22: 1631-1636.
20. CHENG, Y.Q., et al. 2005. A study of the association of iNOS and eNOS gene polymorphism with portal hypertension in liver cirrhosis. Zhonghua Gan Zang Bing Za Zhi 13: 366-369.
21. SHEN, J., et al. 2004. A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer.World J. Gastroenterol. 10: 3278-3283.
22. GONZALEZ-GAY, M.A., et al. 2004. Inducible but not endothelial nitric oxide synthase polymorphism is associated with susceptibility to rheumatoid arthritis in northwest Spain. Rheumatology (Oxford) 43: 1182-1185.
23. SHEN, J., et al. 2002. Study on the relationship between susceptibility of stomach neoplasm cancer and polymorphism of inducible nitric oxide synthase gene. Zhonghua Liu Xing Bing Xue Za Zhi 23: 374-377.
24. CAMPA, D., et al. 2004. Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer. Carcinogenesis 25: 229-235.
25. HU, Z., et al. 2005. A common polymorphism in the 3′UTR of cyclooxygenase 2/prostaglandin synthase 2 gene and risk of lung cancer in a Chinese population. Lung Cancer 48: 11-17.
26. CAMPA, D., et al. 2005. Lack of association between polymorphisms in inflammatory genes and lung cancer risk. Cancer Epidemiol. Biomarkers Prev. 14: 538-539.
27. SIEZEN, C.L., et al. 2005. Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption. Carcinogenesis 26: 449-457.
28. COX, D.G., et al. 2004. Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer. Br. J. Cancer 91: 339-343.
29. TAJOURI, L., et al. 2004. Investigation of an inducible nitric oxide synthase gene (NOS2A) polymorphism in a multiple sclerosis population. Brain Res. Bull. 64: 9-13.