-
1
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999; 17: 2639-48.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
2
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel CL, Cobleigh MA, Tripathy D et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002; 20: 719-26.
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
3
-
-
0027290650
-
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
-
Baselga J, Norton L, Masui L et al. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 1993; 85: 1327-33.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1327-1333
-
-
Baselga, J.1
Norton, L.2
Masui, L.3
-
4
-
-
0032127350
-
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
-
Baselga J, Norton L, Albanell J et al. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 1998; 58: 2825-31.
-
(1998)
Cancer Res
, vol.58
, pp. 2825-2831
-
-
Baselga, J.1
Norton, L.2
Albanell, J.3
-
5
-
-
2942659576
-
Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer
-
Pegram M, Hsu S, Lewis G et al. Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer. J Natl Cancer Inst 2004; 96: 739-49.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 739-749
-
-
Pegram, M.1
Hsu, S.2
Lewis, G.3
-
6
-
-
0033118889
-
Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
-
Pegram M, Hsu S, Lewis G et al. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene 1999; 18: 2241-51.
-
(1999)
Oncogene
, vol.18
, pp. 2241-2251
-
-
Pegram, M.1
Hsu, S.2
Lewis, G.3
-
7
-
-
2942659576
-
Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer
-
Pegram M, Konecny GE, O'Callaghan C et al. Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer. J Natl Cancer Inst 2004; 19: 739-49.
-
(2004)
J Natl Cancer Inst
, vol.19
, pp. 739-749
-
-
Pegram, M.1
Konecny, G.E.2
O'Callaghan, C.3
-
8
-
-
0028196666
-
In vitro antiproliferative activity of docetaxel (Taxotere), paclitaxel (Taxol) and cisplatin against human tumour and normal bone marrow cells
-
Braakhuis BJ, Hill BT, Dietel M et al. In vitro antiproliferative activity of docetaxel (Taxotere), paclitaxel (Taxol) and cisplatin against human tumour and normal bone marrow cells. Anticancer Res 1994; 14: 205-8.
-
(1994)
Anticancer Res
, vol.14
, pp. 205-208
-
-
Braakhuis, B.J.1
Hill, B.T.2
Dietel, M.3
-
9
-
-
0000076620
-
Cellular uptake and efflux of docetaxel and paclitaxel in P388 cell line
-
Riou JF, Petigenet O, Combeau C et al. Cellular uptake and efflux of docetaxel and paclitaxel in P388 cell line. Proc Am Assoc Cancer Res 1994; 35: 385.
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
, pp. 385
-
-
Riou, J.F.1
Petigenet, O.2
Combeau, C.3
-
10
-
-
0027467778
-
Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition
-
Diaz JF, Andreu JM. Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition. Biochemistry 1993; 32: 2747-55.
-
(1993)
Biochemistry
, vol.32
, pp. 2747-2755
-
-
Diaz, J.F.1
Andreu, J.M.2
-
11
-
-
0029908543
-
Influence of microtubule-associated proteins on the differential effects of paclitaxel and docetaxel
-
Fromes Y, Gounon P, Veitia R et al. Influence of microtubule-associated proteins on the differential effects of paclitaxel and docetaxel. J Protein Chem 1996; 15: 377-88.
-
(1996)
J Protein Chem
, vol.15
, pp. 377-388
-
-
Fromes, Y.1
Gounon, P.2
Veitia, R.3
-
13
-
-
0031035693
-
Bcl2 is the guardian of microtubule integrity
-
Haldar S, Basu A, Croce CM. Bcl2 is the guardian of microtubule integrity. Cancer Res 1997; 57: 229-33.
-
(1997)
Cancer Res
, vol.57
, pp. 229-233
-
-
Haldar, S.1
Basu, A.2
Croce, C.M.3
-
14
-
-
1842614241
-
Docetaxel combined with trastuzumab is an active regimen in HER-2 3+ overexpressing and fluorescent in situ hybridization-positive metastatic breast cancer: A multi-institutional phase II trial
-
Tedesco KL, Thor AD, Johnson DH et al. Docetaxel combined with trastuzumab is an active regimen in HER-2 3+ overexpressing and fluorescent in situ hybridization-positive metastatic breast cancer: A multi-institutional phase II trial. J Clin Oncol 2004; 22: 1071-7.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1071-1077
-
-
Tedesco, K.L.1
Thor, A.D.2
Johnson, D.H.3
-
15
-
-
2942691785
-
Results of two open-label, multicenter phase II studies of docetaxel, platinum salts, and trastuzumab in HER2-positive advanced breast cancer
-
Pegram MD, Pienkowski T, Northfelt DW et al. Results of two open-label, multicenter phase II studies of docetaxel, platinum salts, and trastuzumab in HER2-positive advanced breast cancer. J Natl Cancer Inst 2004; 96: 759-69.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 759-769
-
-
Pegram, M.D.1
Pienkowski, T.2
Northfelt, D.W.3
-
16
-
-
0041885349
-
Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: Multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm
-
Burstein HJ, Harris LN, Marcom PK et al. Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm. J Clin Oncol 2003; 21: 2889-95.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2889-2895
-
-
Burstein, H.J.1
Harris, L.N.2
Marcom, P.K.3
-
17
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353: 1659-72.
-
(2005)
N Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
18
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005; 353: 1673-84.
-
(2005)
N Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
19
-
-
33645720799
-
Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (ACTH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2 positive early breast cancer patients: BCIRG study
-
Slamon D, Eiermann W, Robert N et al. Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (ACTH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2 positive early breast cancer patients: BCIRG study. Breast Cancer Res Treat 2005: 94 (Suppl 1): S5a.
-
(2005)
Breast Cancer Res Treat
, vol.94
, Issue.SUPPL. 1
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
20
-
-
33344478381
-
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
-
Joensuu H, Kellokumpu-Lehtinen PL, Bono P et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 2006; 354: 809-20.
-
(2006)
N Engl J Med
, vol.354
, pp. 809-820
-
-
Joensuu, H.1
Kellokumpu-Lehtinen, P.L.2
Bono, P.3
-
21
-
-
33645750519
-
Primary treatment with weekly docetaxel (Taxotere) and trastuzumab (Herceptin) for HER-2 overexpressing locally advanced breast cancer
-
Bines J, Murad A, Lago S et al. Primary treatment with weekly docetaxel (Taxotere) and trastuzumab (Herceptin) for HER-2 overexpressing locally advanced breast cancer. Eur J Cancer 2003; 1 (Suppl 5): S114.
-
(2003)
Eur J Cancer
, vol.1
, Issue.SUPPL. 5
-
-
Bines, J.1
Murad, A.2
Lago, S.3
-
22
-
-
18744395754
-
Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: A phase II study
-
Burstein HJ, Harris LN, Gelman R et al. Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: A phase II study. J Clin Oncol 2003; 21: 46-53.
-
(2003)
J Clin Oncol
, vol.21
, pp. 46-53
-
-
Burstein, H.J.1
Harris, L.N.2
Gelman, R.3
-
23
-
-
20544460650
-
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer
-
Buzdar AU, Ibrahim NK, Francis D et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. J Clin Oncol 2005; 23: 3676-85.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3676-3685
-
-
Buzdar, A.U.1
Ibrahim, N.K.2
Francis, D.3
-
24
-
-
33645741588
-
Pathological complete response rate with neoadjuvant trastuzumab and decetaxel chemotherapy in HER-2 positive (3+) locally advanced breast cancer (Abstract no. 128P)
-
Coudert BP, Arnould L, Moreau L, et al. Pathological complete response rate with neoadjuvant trastuzumab and decetaxel chemotherapy in HER-2 positive (3+) locally advanced breast cancer (Abstract no. 128P). Ann Oncol 2004; 15 (Suppl 3): 34.
-
(2004)
Ann Oncol
, vol.15
, Issue.SUPPL. 3
, pp. 34
-
-
Coudert, B.P.1
Arnould, L.2
Moreau, L.3
-
25
-
-
33645727729
-
Preoperative trastuzumab and vinorelbine is a well-tolerated, active regimen for Her2, 3+/FISH+ stage II/III breast cancer
-
(Abstract no. 397)
-
Harris LN, Burstein H, Gelman R et al. Preoperative trastuzumab and vinorelbine is a well-tolerated, active regimen for Her2, 3+/FISH+ stage II/III breast cancer (Abstract no. 397). Eur J Cancer 2003; 1 (Suppl 5): S121.
-
(2003)
Eur J Cancer
, vol.1
, Issue.SUPPL. 5
-
-
Harris, L.N.1
Burstein, H.2
Gelman, R.3
-
26
-
-
33645746993
-
Neoadjuvant herceptin/taxotere/cisplatin in the treatment of locally advanced and inflammatory breast cancer
-
(Abstract no. 196) May Orlando, FL, USA
-
Hurley J, Dolny P, Silva O et al. Neoadjuvant herceptin/taxotere/ cisplatin in the treatment of locally advanced and inflammatory breast cancer (Abstract no. 196). 38th Annual Meeting of the American Society of Clinical Oncology, 18-21 May 2002, Orlando, FL, USA.
-
(2002)
38th Annual Meeting of the American Society of Clinical Oncology
, pp. 18-21
-
-
Hurley, J.1
Dolny, P.2
Silva, O.3
-
27
-
-
9144241006
-
Neoadjuvant trastuzumab and docetaxel in breast cancer: Preliminary results
-
Van Pelt AE, Mohsin S, Elledge RM et al. Neoadjuvant trastuzumab and docetaxel in breast cancer: Preliminary results. Clin Breast Cancer 2003; 4: 348-53.
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 348-353
-
-
Van Pelt, A.E.1
Mohsin, S.2
Elledge, R.M.3
-
28
-
-
33748990291
-
Response and cardiac toxicity of trastuzumab given in conjunction with weekly paclitaxel after doxorubicin/cyclophosphamide
-
Kelly H, Kimmick G, Dees EC et al. Response and cardiac toxicity of trastuzumab given in conjunction with weekly paclitaxel after doxorubicin/cyclophosphamide. Clin Breast Cancer 2006; 7: 237-43.
-
(2006)
Clin Breast Cancer
, vol.7
, pp. 237-243
-
-
Kelly, H.1
Kimmick, G.2
Dees, E.C.3
-
29
-
-
32944477239
-
Neoadjuvant therapy with trastuzumab, paclitaxel and epirubicin for HER-2-positive operable breast cancer
-
Ahluwalia MS, Daw HA. Neoadjuvant therapy with trastuzumab, paclitaxel and epirubicin for HER-2-positive operable breast cancer. J Clin Oncol 2005; 20: 7759-60.
-
(2005)
J Clin Oncol
, vol.20
, pp. 7759-7760
-
-
Ahluwalia, M.S.1
Daw, H.A.2
-
30
-
-
0028912598
-
Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
-
Hurwitz E, Stancovski I, Sela M et al. Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake. Proc Natl Acad Sci USA 1995; 92: 3353-7.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3353-3357
-
-
Hurwitz, E.1
Stancovski, I.2
Sela, M.3
-
31
-
-
0032851961
-
Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin)
-
Sliwkowski MX, Lofgren JA, Lewis GD et al. Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin). Semin Oncol 1999; 26: 60-70.
-
(1999)
Semin Oncol
, vol.26
, pp. 60-70
-
-
Sliwkowski, M.X.1
Lofgren, J.A.2
Lewis, G.D.3
-
32
-
-
0035874981
-
Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
-
Molina MA, Codony-Servat J, Albanell J et al. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res, 2001; 84: 4744-9.
-
(2001)
Cancer Res
, vol.84
, pp. 4744-4749
-
-
Molina, M.A.1
Codony-Servat, J.2
Albanell, J.3
-
33
-
-
0031785720
-
Use of rituximab, the new FDA-approved antibody
-
Leget GA, Czuczman MS. Use of rituximab, the new FDA-approved antibody. Curr Opin Oncol 1998; 10: 548-51.
-
(1998)
Curr Opin Oncol
, vol.10
, pp. 548-551
-
-
Leget, G.A.1
Czuczman, M.S.2
-
34
-
-
0033230622
-
Clinical applications of anti-CD20 antibodies
-
Gopal AK, Press OW. Clinical applications of anti-CD20 antibodies. J Lab Clin Med 1999; 134: 445-50.
-
(1999)
J Lab Clin Med
, vol.134
, pp. 445-450
-
-
Gopal, A.K.1
Press, O.W.2
-
35
-
-
0642312825
-
Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance
-
Smith MR. Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance. Oncogene 2003; 22: 7359-68.
-
(2003)
Oncogene
, vol.22
, pp. 7359-7368
-
-
Smith, M.R.1
-
36
-
-
0030611643
-
FcgRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell FcgRIIIa, independently of the FcgRIIIa-48L/R/H phenotype
-
Koene HR, Kleijer M, Algra J, von Roos D, dem Born AE, de Haas M. FcgRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell FcgRIIIa, independently of the FcgRIIIa-48L/R/H phenotype. Blood 1997; 90: 1109-14.
-
(1997)
Blood
, vol.90
, pp. 1109-1114
-
-
Koene, H.R.1
Kleijer, M.2
Algra, J.3
von Roos, D.4
dem Born, A.E.5
de Haas, M.6
-
37
-
-
0030611089
-
A novel polymorphism of FcgRIIIa (CD16) alters receptor function and predisposes to autoimmune disease
-
Wu J, Edberg JC, Redecha PB et al. A novel polymorphism of FcgRIIIa (CD16) alters receptor function and predisposes to autoimmune disease. J Clin Invest 1997; 100: 1059-70.
-
(1997)
J Clin Invest
, vol.100
, pp. 1059-1070
-
-
Wu, J.1
Edberg, J.C.2
Redecha, P.B.3
-
38
-
-
4444372733
-
Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumours overexpressing HER2
-
Gennari R, Menard S, Fagnoni F et al. Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumours overexpressing HER2. Clin Cancer Res 2004; 10: 5650-5.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5650-5655
-
-
Gennari, R.1
Menard, S.2
Fagnoni, F.3
-
39
-
-
31444451572
-
Trastuzumab-based treatment of HER2-positive breast cancer: An antibody-dependent cellular cytotoxicity mechanism?
-
Arnould L, Gelly M, Penault-Liorca F et al. Trastuzumab-based treatment of HER2-positive breast cancer: An antibody-dependent cellular cytotoxicity mechanism? Br J Cancer 2006; 94: 259-67.
-
(2006)
Br J Cancer
, vol.94
, pp. 259-267
-
-
Arnould, L.1
Gelly, M.2
Penault-Liorca, F.3
-
40
-
-
0037149539
-
Tumour biology: Herceptin acts as an anti-angiogenic cocktail
-
Izumi Y, Xu L, di Tomaso E et al. Tumour biology: Herceptin acts as an anti-angiogenic cocktail. Nature 2002; 416: 279-80.
-
(2002)
Nature
, vol.416
, pp. 279-280
-
-
Izumi, Y.1
Xu, L.2
di Tomaso, E.3
-
41
-
-
2542526069
-
P27 (kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells
-
Nahta R, Takahashi T, Ueno NT et al. P27 (kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells. Cancer Res 2004; 64: 2343-6.
-
(2004)
Cancer Res
, vol.64
, pp. 2343-2346
-
-
Nahta, R.1
Takahashi, T.2
Ueno, N.T.3
-
42
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan KH, Zhou X et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004; 6: 117-27.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
-
43
-
-
0035915421
-
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu Y, Zi X, Zhao Y et al. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 2001; 93: 1852-7.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1852-1857
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
-
44
-
-
32944461545
-
Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells
-
Konecny GE, Pegram MD, Venkatesan N et al. Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells. Cancer Res 2006; 66: 1630-9.
-
(2006)
Cancer Res
, vol.66
, pp. 1630-1639
-
-
Konecny, G.E.1
Pegram, M.D.2
Venkatesan, N.3
-
45
-
-
23844544970
-
A phase I, open label study of lapatinib (GW572016) plus trastuzumab; a clinically active regimen
-
(Abstract no. 559)
-
Storniolo A, Burris H, Pegram M et al. A phase I, open label study of lapatinib (GW572016) plus trastuzumab; a clinically active regimen (Abstract no. 559). J Clin Oncol 2005; 23 (Suppl 16): S18.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL. 16
-
-
Storniolo, A.1
Burris, H.2
Pegram, M.3
-
46
-
-
4544284509
-
A phase II, open label, multicenter study of GW572016 in patients with trastuzumab-refractory metastatic breast cancer
-
Blackwell KL, Kaplan EH, Franco SX et al. A phase II, open label, multicenter study of GW572016 in patients with trastuzumab-refractory metastatic breast cancer. J Clin Oncol 2004; 22 (Suppl 14): 3006.
-
(2004)
J Clin Oncol
, vol.22
, Issue.SUPPL. 14
, pp. 3006
-
-
Blackwell, K.L.1
Kaplan, E.H.2
Franco, S.X.3
-
47
-
-
14944343011
-
A phase II, open label, multicenter study of GW572016 in two cohorts of patients with advanced or metastatic breast cancer who have progressed while receiving trastuzumab-containing regimens
-
Burstein H, Storniolo AM, Franco S et al. A phase II, open label, multicenter study of GW572016 in two cohorts of patients with advanced or metastatic breast cancer who have progressed while receiving trastuzumab-containing regimens. Ann Oncol 2004; 15 (Suppl 13): A103.
-
(2004)
Ann Oncol
, vol.15
, Issue.SUPPL. 13
-
-
Burstein, H.1
Storniolo, A.M.2
Franco, S.3
-
48
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
Agus DB, Akita RW, Fox WD et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell 2002; 2: 127-37.
-
(2002)
Cancer Cell
, vol.2
, pp. 127-137
-
-
Agus, D.B.1
Akita, R.W.2
Fox, W.D.3
-
49
-
-
1942474587
-
The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
-
Nahta R, Hung MC, Esteva FJ. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res 2004; 64: 2343-6.
-
(2004)
Cancer Res
, vol.64
, pp. 2343-2346
-
-
Nahta, R.1
Hung, M.C.2
Esteva, F.J.3
-
50
-
-
33645651433
-
A phase II trial with trastuzumab and pertuzumab in patients with HER2-overexpressed locally advanced and metastatic breast cancer
-
Walshe JM, Denduluri N, Berman AW et al. A phase II trial with trastuzumab and pertuzumab in patients with HER2-overexpressed locally advanced and metastatic breast cancer. Clin Breast Cancer 2006; 6: 535-9.
-
(2006)
Clin Breast Cancer
, vol.6
, pp. 535-539
-
-
Walshe, J.M.1
Denduluri, N.2
Berman, A.W.3
-
51
-
-
0037392444
-
Issues and progress with protein kinase inhibitors for cancer treatment
-
Dancey J, Sausville EA. Issues and progress with protein kinase inhibitors for cancer treatment. Nat Rev Drug Discov 2003; 2: 296-313.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 296-313
-
-
Dancey, J.1
Sausville, E.A.2
-
52
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
Neshat MS, Mellinghoff IK, Tran C et al. Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc Natl Acad Sci USA 2001; 98: 10 314-19.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
-
53
-
-
0037474276
-
The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity
-
Shinkawa T, Nakamura K, Yamane N et al. The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity. J Biol Chem 2003; 278: 3466-73.
-
(2003)
J Biol Chem
, vol.278
, pp. 3466-3473
-
-
Shinkawa, T.1
Nakamura, K.2
Yamane, N.3
-
54
-
-
12144289636
-
Defucosylated anti-CC chemokine receptor 4 IgG1 with enhanced antibody-dependent cellular cytotoxicity shows potent therapeutic activity to T cell leukemia and lymphoma
-
Niwa R, Shoji-Hosaka E, Sakurada M et al. Defucosylated anti-CC chemokine receptor 4 IgG1 with enhanced antibody-dependent cellular cytotoxicity shows potent therapeutic activity to T cell leukemia and lymphoma. Cancer Res 2004; 64: 2127-33.
-
(2004)
Cancer Res
, vol.64
, pp. 2127-2133
-
-
Niwa, R.1
Shoji-Hosaka, E.2
Sakurada, M.3
-
55
-
-
1242317024
-
Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgRIIIa
-
Okazaki A, Shoji-Hosaka E, Nakamura K et al. Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgRIIIa. J Mol Biol 2004; 336: 1239-49.
-
(2004)
J Mol Biol
, vol.336
, pp. 1239-1249
-
-
Okazaki, A.1
Shoji-Hosaka, E.2
Nakamura, K.3
-
56
-
-
4644245701
-
Enhancement of the antibody-dependent cellular cytotoxicity of low-fucose IgG1 is independent of FcgRIIIa functional polymorphism
-
Niwa R, Hatanaka S, Shoji-Hosaka E et al. Enhancement of the antibody-dependent cellular cytotoxicity of low-fucose IgG1 is independent of FcgRIIIa functional polymorphism. Clin Cancer Res 2004; 10: 6248-55.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6248-6255
-
-
Niwa, R.1
Hatanaka, S.2
Shoji-Hosaka, E.3
-
57
-
-
34247854443
-
A non-fucosylated anti-HER2 antibody augments antibody-dependent cellular cytotoxicity of breast cancer patients
-
Suzuki E, Niwa R, Sagi S et al. A non-fucosylated anti-HER2 antibody augments antibody-dependent cellular cytotoxicity of breast cancer patients. Clin Cancer Res 2007; 13: 1875-82.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1875-1882
-
-
Suzuki, E.1
Niwa, R.2
Sagi, S.3
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