Ksp-cadherin gene promoter. I. Characterization and renal epithelial cell-specific activity

American Journal of Physiology - Renal Physiology

Volumn 277, Issue 4 46-4, 1999, Pages

  Whyte, Dilys A ^a,c   Li, Congyi ^a   Thomson, R Brent ^a   Nix, Stagey L ^a   Zanjani, Reza ^a   Karp, Sharon L ^b   Aronson, Peter S ^a   Igarashi, Peter ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cell adhesion; Gene regulation; Kidney specific; Transcription factor

Indexed keywords

CADHERIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL SPECIFICITY; GENE CONTROL; KIDNEY EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

EID: 0032750545     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.277.4.f587     Document Type: Article

References (34)

1. Andrews, N. C., and D. V. Faller. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19: 2499, 1991.
2. Behrens, J., O. Löwrick, L. Klein-Hitpass, and W. Birchmeier. The E-cadherin promoter: functional analysis of a GC-rich region and an epithelial cell-specific palindromic regulatory element. Proc. Natl. Acad. Sci. USA 88: 11495-11499, 1991.
3. 2+-dependent cell adhesion molecule expressed in liver and intestine. J. Cell Biol. 125: 1353-1369, 1994.
4. Blaurock, M. C., N. A. Rebouças, J. L. Kusnezov, and P. Igarashi. Phylogenetically conserved sequences in the promoter of the rabbit sodium-hydrogen exchanger isoform 1 gene (NHE1/ SLC9A1).Biochim. Biophys. Acta 1262: 159-163, 1995.
5. de Simone, V., and R. Cortese. Transcription factors and liver-specific genes. Biochim. Biophys. Acta 1132: 119-126, 1992.
6. Faraldo, M. L. M., and A. Cano. The 5′ flanking sequence of the mouse P-cadherin gene: homologies to 5′ sequences of the E-cadherin gene and identification of a first 215 base-pair intron. J. Mol. Biol. 231: 935-941, 1993.
7. Furuno, M., S. Uchida, F. Marumo, and S. Sasaki. Repressive regulation of the aquaporin-2 gene. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F854-F860, 1996.
8. Geiger, B., and O. Ayalon. Cadherins. Annu. Rev. Cell Biol. 8: 307-332, 1992.
9. Hennig, G., O. Löwrick, W. Birchmeier, and J. Behrens. Mechanisms identified in the transcriptional control of epithelial gene expression. J. Biol. Chem. 271: 595-602, 1996.
10. i cotransporter gene. Am. J. Physiol. 274 (Renal Physiol. 43): F197-F204, 1998.
11. 10a. Igarashi, P., C. S. Shashikant, R. B. Thomson, D. A. Whyte, S. Liu-Chen, F. H. Ruddle, and P. S. Aronson. Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice. Am. J. Physiol. 277 (Renal Physiol. 46): F599-F610, 1999.
12. Igarashi, P., G. B. Vanden Heuvel, J. A. Payne, and B. Forfaush, III. Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F405-F418, 1995.
13. Igarashi, P., D. A. Whyte, K. Li, and G. T. Nagami. Cloning and kidney cell-specific activity of the promoter of the murine renal Na-K-Cl cotransporter gene. J. Biol. Chem. 271: 9666-9674, 1996.
14. Javahery, R., A. Khachi, K. Lo, B. Zenzie-Gregory, and S. T. Smale. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 14: 116-127, 1994.
15. Karp, S. L., A. Ortiz-Arduan, S. Li, and E. G. Neilson. Epithelial differentiation of metanephric mesenchymal cells after stimulation with hepatocyte growth factor or embryonic spinal cord. Proc. Natl. Acad. Sci. USA 91: 5286-5290, 1994.
16. Karp, S. L., and K. Phipps. The novel zinc finger protein EEK3 is expressed in epithelial cells of the developing kidney (Abstract). J. Am. Soc. Nephrol. 9: 363, 1998.
17. Lai, E., K. L. Clark, S. K. Burley, and J. E. Darnell, Jr. Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function. Proc. Natl. Acad. Sci. USA 90: 10421-10423, 1993.
18. 2 receptor gene. Pflügers Arch. 430: 12-18, 1995.
19. Moser, M., A. Pscherer, C. Roth, J. Becker, G. Mucher, K. Zerres, C. Dixkens, J. Weis, L. Guay-Woodford, R. Buettner, and R. Fassler. Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2β. Genes Dev. 11: 1938-1948, 1997.
20. Murre, C., and D. Baltimore. The helix-loop-helix motif: structure and function. In: Transcriptional Regulation, edited by S. L. McKnight and K. R. Yamamoto. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 1992, p. 861-879.
21. Nelson, R. D., P. Stricklett, C. Gustafson, A. Stevens, D. Ausiello, D. Brown, and D. E. Kohan. Expression of an AQP2 Cre recombinase transgene in kidney and male reproductive system of transgenic mice. Am. J. Physiol. 275 (Cell Physiol. 44): C216-C226, 1998.
22. Overdier, D. G., H. Ye, R. S. Peterson, D. E. Clevidence, and R. H. Costa. The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney. J. Biol. Chem. 272: 13725-13730, 1997.
23. Quaggin, S. E., G. B. Vanden Heuvel, K. Golden, R. Bodmer, and P. Igarashi. Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut. J. Biol. Chem. 271: 22624-22634, 1996.
24. Rai, T., S. Uchida, F. Marumo, and S. Sasaki. Cloning of rat and mouse aquaporin-2 gene promoters and identification of a negative cis-regulatory element. Am. J. Physiol. 273 (Renal Physiol. 42): F264-F273, 1997.
25. Ranchman, M. I., S. K. Nigam, E. Delpire, and S. R. Gullans. An osmotically tolerant inner medullary collecting duct cell line derived from an SV40 transgenic mouse. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F416-F424, 1993.
26. Sepulveda, S. R., S. L. Huang, R. M. Lebovitz, and M. W. Lieberman. A 346-base pair region of the mouse γ-glutamyl transpeptidase type II promoter contains sufficient cis-acting elements for the kidney-restricted expression in transgenic mice. J. Biol. Chem. 272: 11959-11967, 1997.
27. Takeichi, M. Cadherins: a molecular family important in selective cell-cell adhesion. Annu. Rev. Biochem. 59: 237-252, 1990.
28. Thomson, R. B., P. Igarashi, D. Biemesderfer, R. Kim, A. Abu-Alfa, M. Soleimani, and P. S. Aronson. Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. J. Biol. Chem. 270: 17594-17601, 1995.
29. Thomson, R. B., D. C. Ward, S. E. Quaggin, P. Igarashi, Z. E. Muckler, and P. S. Aronson. cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin. Genomics 51: 445-451, 1998.
30. Uchida, S., Y. Matsumura, T. Rai, S. Sasaki, and F. Marumo. Regulation of aquaporin-2 gene transcription by GATA-3. Biochem. Biophys. Res. Commun. 232: 65-68, 1997.
31. Uchida, S., T. Rai, H. Yatsushige, Y. Matsumura, M. Kawasaki, S. Sasaki, and F. Maruno. Isolation and characterization of kidney-specific ClC-K1 chloride channel gene promoter. Am. J. Physiol. 274 (Renal Physiol. 43): F602-F610, 1998.
32. Uchida, S., S. Sasaki, K. Fushimi, and F. Marumo. Isolation of human aquaporin-CD gene. J. Biol. Chem. 269: 23451-23455, 1994.
33. Whyte, D. A., R. B. Thomson, S. L. Nix, S. L. Karp, P. S. Aronson, and P. Igarashi. Cloning and characterization of the mouse Ksp-cadherin gene promoter (Abstract). J. Am. Soc. Nephrol. 9: 369, 1998.
34. Xanthopoulos, K. G., V. R. Prezioso, W. S. Chen, F. M. Sladek, R. Cortese, and J. R. Darnell, Jr. The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription. Proc. Natl. Acad. Sci. USA 88: 3807-3811, 1991.