Targeting CD40

Leukemia and Lymphoma

Volumn 48, Issue 2, 2007, Pages 229-231

  Wang, Eunice S ^a,b   Wetzler, Meir ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD40 ANTIGEN; CD40 LIGAND; CD40 LIGAND MONOCLONAL ANTIBODY; FLUOROURACIL; SGN 40; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG; MONOCLONAL ANTIBODY;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; B CELL LYMPHOMA; CANCER REGRESSION; CANCER SURVIVAL; CELL COUNT; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DISEASE SEVERITY; DRUG RESPONSE; DRUG TARGETING; ENZYME INHIBITION; HAIRY CELL LEUKEMIA; HUMAN; LEUKEMIA CELL; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SOLID TUMOR; T LYMPHOCYTE ACTIVATION; UPREGULATION; VIRAL GENE THERAPY; ANIMAL; CELL MEMBRANE; IMMUNOLOGY; LYMPHOMA; METABOLISM; PATHOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD40; CELL MEMBRANE; HUMANS; LYMPHOMA;

EID: 34247849314     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190601186010     Document Type: Note

References (30)

1. Banchereau, J., Bazan, F., Blanchard, D., Briere, F., Galizzi, J. P. and van Kooten, C. (1994) The CD40 antigen and its ligand. Annu Rev Immunol, 12, pp. 881-922.
2. Szocinski, J. L., Khaled, A. R., Hixon, J., Halverson, D., Funakoshi, S. and Fanslow, W. C. (2002) Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: Induction of bax. Blood, 100, pp. 217-223.
3. Hollenbaugh, D., Grosmaire, L. S., Kullas, C. D., Chalupny, N. J., Braesch-Andersen, S. and Noelle, R. J. (1992) The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: Expression of a soluble form of gp39 with B cell co-stimulatory activity. Embo J, 11, pp. 4313-4321.
4. Graf, D., Korthauer, U., Mages, H. W., Senger, G. and Kroczek, R. A. (1992) Cloning of TRAP, a ligand for CD40 on human T cells. Eur J Immunol, 22, pp. 3191-3194.
5. Peitsch, M. C. and Jongeneel, C. V. (1993) A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors. Int Immunol, 5, pp. 233-238.
6. Arch, R. H., Gedrich, R. W. and Thompson, C. B. (1998) Tumor necrosis factor receptor-associated factors (TRAFs)-a family of adapter proteins that regulates life and death. Genes Dev, 12, pp. 2821-2830.
7. Chung, J. Y. and Park, Y. C. (2002) All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J Cell Sci, 115, pp. 679-688.
8. Fluckiger, A. C., Rossi, J. F., Bussel, A., Bryon, P., Banchereau, J. and Defrance, T. (1992) Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors. Blood, 80, pp. 3173-3181.
9. Crawford, D. H. and Catovsky, D. (1993) In vitro activation of leukaemic B cells by interleukin-4 and antibodies to CD40. Immunology, 80, pp. 40-44.
10. Kluin-Nelemans, H. C., Beverstock, G. C., Mollevanger, P., Wessels, H. W., Hoogendoorn, E. and Willemze, R. (1994) Proliferation and cytogenetic analysis of hairy cell leukemia upon stimulation via the CD40 antigen. Blood, 84, pp. 3134-3141.
11. Johnson, P. W., Watt, S. M., Betts, D. R., Davies, D., Jordan, S. and Norton, A. J. (1993) Isolated follicular lymphoma cells are resistant to apoptosis and can be grown in vitro in the CD40/stromal cell system. Blood, 82, pp. 1848-1857.
12. Carbone, A., Gloghini, A., Gattei, V., Aldinucci, D., Degan, M. and De Paoli, P. (1995) Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines. Blood, 85, pp. 780-789.
13. Liu, Y. J., Mason, D. Y., Johnson, G. D., Abbot, S., Gregory, C. D. and Hardie, D. L. (1991) Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis. Eur J Immunol, 21, pp. 1905-1910.
14. Funakoshi, S., Longo, D. L., Beckwith, M., Conley, D. K., Tsarfaty, G., Tsarfaty, I. and Armitage, R. J. (1994) Inhibition of human B-cell lymphoma growth by CD40 stimulation. Blood, 83, pp. 2787-2794.
15. + T-cell induction of Fas-mediated apoptosis in Burkitt's lymphoma B cells. Blood, 88, pp. 1375-1382.
16. Young, L. S., Eliopoulos, A. G., Gallagher, N. J. and Dawson, C. W. (1998) CD40 and epithelial cells: Across the great divide. Immunol Today, 19, pp. 502-506.
17. Pellat-Deceunynck, C., Amiot, M., Robillard, N., Wijdenes, J. and Bataille, R. (1996) CD11a-CD18 and CD102 interactions mediate human myeloma cell growth arrest induced by CD40 stimulation. Cancer Res, 56, pp. 1909-1916.
18. Westendorf, J. J., Ahmann, G. J., Armitage, R. J., Spriggs, M. K., Lust, J. A. and Greipp, P. R. (1994) CD40 expression in malignant plasma cells. Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line. J Immunol, 152, pp. 117-128.
19. Francisco, J. A. and Siegall, C. B. (1998) Single-chain immunotoxins targeted to CD40 for the treatment of human B-lineage hematologic malignancies. Leuk Lymphoma, 30, pp. 237-245.
20. Geldart, T. and Illidge, T. (2005) Anti-CD 40 monoclonal antibody. Leuk Lymphoma, 46, pp. 1105-1113.
21. Farahani, M., Treweeke, A. T., Toh, C. H., Till, K. J., Harris, R. J. and Cawley, J. C. (2005) Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells. Leukemia, 19, pp. 524-530.
22. Vonderheide, R. H., Dutcher, J. P., Anderson, J. E., Eckhardt, S. G., Stephans, K. F. and Razvillas, B. (2001) Phase I study of recombinant human CD40 ligand in cancer patients. J Clin Oncol, 19, pp. 3280-3287.
23. Wierda, W. G., Cantwell, M. J., Woods, S. J., Rassenti, L. Z., Prussak, C. E. and Kipps, T. J. (2000) CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia. Blood, 96, pp. 2917-2924.
24. Takahashi, S., Yotnda, P., Rousseau, R. F., Mei, Z., Smith, S. and Rill, D. (2001) Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma. Cancer Gene Ther, 8, pp. 378-387.
25. Messmer, D. and Kipps, T. J. (2005) CD154 gene therapy for human B-cell malignancies. Ann NY Acad Sci, 1062, pp. 51-60.
26. Bonsignori, M., D'Costa, S., Surman, S. and Hurwitz, J. L. (2007) A combination of 5-fluorouracil and membrane-bound antibody inhibits B-cell lymphoma growth in a mouse model system. Leuk Lymphoma, 48, pp. 406-409.
27. Law, C. L., Gordon, K. A., Collier, J., Klussman, K., McEarchern, J. A. and Cerveny, C. G. (2005) Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40. Cancer Res, 65, pp. 8331-8338.
28. Tai, Y. T., Catley, L. P., Mitsiades, C. S., Burger, R., Podar, K. and Shringpaure, R. (2004) Mechanisms by which SGN-40, a humanized anti-CD40 antibody, induces cytotoxicity in human multiple myeloma cells: Clinical implications. Cancer Res, 64, pp. 2846-2852.
29. Buske, C., Weigert, O., Dreyling, M., Unterhalt, M. and Hiddemann, W. (2006) Current status and perspective of antibody therapy in follicular lymphoma. Haematologica, 91, pp. 104-112.
30. Konecny, G. E. and Pegram, M. D. (2004) Gemcitabine in combination with trastuzumab and/or platinum salts in breast cancer cells with HER2 overexpression. Oncology (Huntingt), 18, pp. 32-36.