Synthesis and biological evaluation of some α-[6-(1′- carbamoylalkylthio)-1 H-pyrazolo[3,4-D]pyrimidin-4-yl]thioalkylcarboxamide acyclonucleosides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 26, Issue 4, 2007, Pages 335-345

  Moukha Chafiq, Omar ^a,e   Taha, Mohamed Labd ^a   Mouna, Abdelmalek ^a   Lazrek, Hassan Bihi ^b   Vasseur, Jean Jacques ^c   De Clercq, Erik ^d  

^a Faculte des Sciences   (Morocco)

^b FACULTÉ DES SCIENCES SEMLALIA   (Morocco)

^c UNIV MONTPELLIER   (France)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^e SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Acyclic nucleosides; Disubstituted pyrazolo 3,4 d pyrimidines

Indexed keywords

ALPHA [1 (2 HYDROXYETHOXY)METHYL 6 (1' CARBAMOYLETHYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOPROPANAMIDE; ALPHA [1 (2 HYDROXYETHOXY)METHYL 6 (1' CARBAMOYLPROPYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOBUTANAMIDE; ALPHA [1 (2 HYDROXYETHOXY)METHYL 6 CARBAMOYLMETHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOACETAMIDE; ALPHA [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 6 (1' CARBAMOYLETHYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOPROPANAMIDE; ALPHA [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 6 (1' CARBAMOYLPROPYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOBUTANAMIDE; ALPHA [1 (2,3 DIHYDROXY 1 PROPOXY)METHYL 6 CARBAMOYLMETHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOACETAMIDE; ALPHA [1 (4 HYDROXYBUTYL) 6 (1' CARBAMOYLETHYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOPROPANAMIDE; ALPHA [1 (4 HYDROXYBUTYL) 6 (1' CARBAMOYLPROPYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOBUTANAMIDE; ALPHA [1 (4 HYDROXYBUTYL) 6 CARBAMOYLMETHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOACETAMIDE; ETHYL ALPHA [1 (2 ACETOXYETHOXY)METHYL 6 (1' CARBOETHOXYETHYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOPROPIONATE; ETHYL ALPHA [1 (2 ACETOXYETHOXY)METHYL 6 (1' CARBOETHOXYPROPYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOBUTYRATE; ETHYL ALPHA [1 (2 ACETOXYETHOXY)METHYL 6 CARBOETHOXYMETHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOACETATE; ETHYL ALPHA [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 6 (1' CARBOETHOXYETHYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOPROPIONATE; ETHYL ALPHA [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 6 (1' CARBOETHOXYPROPYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOBUTYRATE; ETHYL ALPHA [1 (3 ACETOXY 2 O BENZOYL 1 PROPOXY)METHYL 6 CARBOETHOXYMETHYLTHIO 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOACETATE; ETHYL ALPHA [1 (4 ACETOXYBUTYL) 6 (1' CARBOETHOXYETHYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOPROPIONATE; ETHYL ALPHA [1 (4 ACETOXYBUTYL) 6 (1' CARBOETHOXYPROPYLTHIO) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOBUTYRATE; ETHYL ALPHA [1 (4 ACETOXYBUTYL) 6 CARBOETHOXYMETHYTHIO 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]THIOACETATE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CYTOMEGALOVIRUS; DRUG SYNTHESIS; EVALUATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; VARICELLA ZOSTER VIRUS;

HUMAN HERPESVIRUS 3; HUMAN HERPESVIRUS 5; MYCOBACTERIUM TUBERCULOSIS;

EID: 34247849204     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770701296952     Document Type: Article

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