Multiple molecular markers as predictors of colorectal cancer in patients with normal perioperative serum carcinoembryonic antigen levels

Clinical Cancer Research

Volumn 13, Issue 8, 2007, Pages 2406-2413

  Wang, Jaw Yuan ^a,b   Lin, Shiu Ru ^c   Wu, Deng Chyang ^b   Lu, Chien Yu ^b   Yu, Fang Jung ^b   Hsieh, Jan Sing ^a,b   Cheng, Tian Lu ^c   Koay, Lok Beng ^d   Uen, Yih Huei ^d,e  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARCINOEMBRYONIC ANTIGEN; CYTOKERATIN 19; CYTOKERATIN 20; DIGOXIGENIN; TELOMERASE REVERSE TRANSCRIPTASE; TUMOR MARKER;

ADJUVANT THERAPY; ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; BLOOD SAMPLING; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER STAGING; CLINICAL FEATURE; COLORECTAL CANCER; COLORIMETRY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; FEMALE; FOLLOW UP; GENE OVEREXPRESSION; HUMAN; IMMUNOASSAY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

AGED; CARCINOEMBRYONIC ANTIGEN; COLORECTAL NEOPLASMS; COLORIMETRY; FEMALE; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDE PROBES; PREDICTIVE VALUE OF TESTS; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY;

EID: 34247847913     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-2054     Document Type: Article

References (31)

1. Gold P, Freedman SO. Specific carcinoembryonic antigens of the human digestive system. J Exp Med 1965;122:467-81.
2. Hohenberger P, Schlag PM, Gerneth T, Herfarth C. Pre- and postoperative carcinoembryonic antigen determinations in hepatic resection for colorectal metastases. Predictive value and implications for adjuvant treatment based on multivariate analysis. Ann Surg 1994;219:135-43.
3. Slentz K, Senagore A, Hibbert J, Mazier WP, Talbott TM. Can preoperative and postoperative CEA predict survival after colon cancer resection? Am Surg 1994;60:528-31.
4. McCall JL, Black RB, Rich CA, et al. The value of serum carcinoembryonic antigen in predicting recurrent disease following curative resection of colorectal cancer. Dis Colon Rectum 1994;37:875-81.
5. Wiratkapun S, Kraemer M, Seow-Choen F, Ho YH, Eu KW. High preoperative serum carcinoembryonic antigen predicts metastatic recurrence in potentially curative colonic cancer: results of a five-year study. Dis Colon Rectum 2001;44:231-5.
6. Wichmann MW, Muller C, Hornung HM, Lau-Werner U, Schildberg FW; the Colorectal Cancer Study Group. Results of long-term follow-up after curative resection of Dukes A colorectal cancer. World J Surg 2002;26:732-6.
7. Louhimo J, Carpelan-Holmstrom M, Alfthan H, et al. CA 72-4 and CEA are independent prognostic factors in colorectal cancer. Int J Cancer 2002;101:545-8.
8. Guadagni F, Kantor J, Aloe S, et al. Detection of blood-borne cells in colorectal cancer patients by nested reverse transcription-polymerase chain reaction for carcinoembryonic antigen messenger RNA: longitudinal analyses and demonstration of its potential importance as an adjunct to multiple serum markers. Cancer Res 2001;61:2523-32.
9. Ito S, Nakanishi H, Hirai T, et al. Quantitative detection of CEA expressing free tumor cells in the peripheral blood of colorectal cancer patients during surgery with real-time RT-PCR on a LightCycler. Cancer Lett 2002;183:195-203.
10. Lledo SM, Garcia-Granero E, Dasi F, et al. Real time quantification in plasma of human telomerase reverse transcriptase (hTERT) mRNA in patients with colorectal cancer. Colorectal Dis 2004;6:236-42.
11. Castells A, Boix L, Bessa X, Gargallo L, Pique JM. Detection of colonic cells in peripheral blood of colorectal cancer patients by means of reverse transcriptase and polymerase chain reaction. Br J Cancer 1998;78:1368-72.
12. Wharton RQ, Jonas SK, Glover C, et al. Increased detection of circulating tumor cells in the blood of colorectal carcinoma patients using two reverse transcription-PCR assays and multiple blood samples. Clin Cancer Res 1999;5:4158-63.
13. Wong IH, Yeo W, Chan AT, Law WY, Johnson PJ. Quantitative relationship of the circulating tumor burden assessed by reverse transcription-polymerase chain reaction for cytokeratin 19 mRNA in peripheral blood of colorectal cancer patients with Dukes' stage, serum carcinoembryonic antigen level and tumor progression. Cancer Lett 2001;167:183-91.
14. Wang JY, Wu CH, Lu CY, et al. Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance in the prediction of postoperative metastasis. World J Surg 2006;30:1007-13.
15. Chen YF, Wang JY, Wu CH, et al. Detection the circulating cancer cells with K-ras oncogene using membrane array. Cancer Lett 2005;229:115-22.
16. Wu CH, Lin SR, Yu FJ, et al. Development of a high-throughput membrane-array method for molecular diagnosis of circulating tumor cells in patients with gastric cancers. Int J Cancer 2006;119:373-9.
17. Wang JY, Yeh CS, Chen YF, et al. Development and evaluation of a colorimetric membrane-array method for the detection of circulating tumor cells in the peripheral blood of Taiwanese patients with colorectal cancer. Int J Mol Med 2006;17:737-47.
18. Yeh CS, Wang JY, Wu CH, et al. Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel. Int J Oncol 2006;28:411-20.
19. Sheu CC. Development of a membrane array-based multimarker assay for detection of circulating cancer cells in patients with non-small cell lung cancer. Int J Cancer 2006;119:1419-26.
20. International Union Against Cancer. TNM classification of malignant tumors. 6th ed. New York: Wiley-Liss, Inc.; 2002.
21. Compton C, Fenoglio-Preiser CM, Pettigrew N, Fielding LP. American Joint Committee on Cancer Prognostic Factors Consensus Conference: Colorectal Working Group. Cancer 2000;88:1739-57.
22. McCall JL, Black RB, Rich CA, et al. The value of serum carcino-embryonic antigen in predicting recurrent disease following curative resection of colorectal cancer. Dis Colon Rectum 1994;37:875-81.
23. Ishikawa H, Fujii H, Yamamoto K, et al. Tumor angiogenesis predicts recurrence with normal serum carcinoembryonic antigen in advanced rectal carcinoma patients. Surg Today 1999;29:983-91.
24. Racila E, Euhus D, Weiss AJ, et al. Detection and characterization of carcinoma cells in the blood. Proc Natl Acad Sci U S A 1998;95:4589-94.
25. Hoon DS, Wang Y, Dale PS, et al. Detection of occult melanoma cells in blood with a multiple-marker polymerase chain reaction assay. J Clin Oncol 1995;13:2109-16.
26. Conzelmann M, Linnemann U, Berger MR. Molecular detection of clinical colorectal cancer metastasis: how should multiple markers be put to use? Int J Colorectal Dis 2005;20:137-46.
27. Sher YP, Shih JY, Yang PC, et al. Prognosis of non-small cell lung cancer patients by detecting circulating cancer cells in the peripheral blood with multiple marker genes. Clin Cancer Res 2005;11:173-9.
28. Mori M, Mimori K, Ueo H, et al. Molecular detection of circulating solid carcinoma cells in the peripheral blood: the concept of early systemic disease. Int J Cancer 1996;68:739-43.
29. Molnar B, Ladanyi A, Tanko L, Sreter L, Tulassay Z. Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients. Clin Cancer Res 2001;7:4080-5.
30. O'Sullivan GC, Collins JK, Kelly J, et al. Micrometastases: marker of metastatic potential or evidence of residual disease? Gut 1997;40:512-5.
31. Schuchhardt J, Beule D, Malik A, et al. Normalization strategies for cDNA microarrays. Nucleic Acids Res 2000;28:E47.