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Volumn 1, Issue 2, 2006, Pages 135-140

Phase II trial of gemcitabine-carboplatin-paclitaxel as neoadjuvant chemotherapy for operable non-small cell lung cancer

Author keywords

Neoadjuvant chemotherapy; Non small cell lung cancer; Triplet regimen

Indexed keywords

ANTIHISTAMINIC AGENT; CARBOPLATIN; CIMETIDINE; CISPLATIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DIPHENHYDRAMINE; DOCETAXEL; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IFOSFAMIDE; MITOMYCIN; PACLITAXEL; RANITIDINE; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; DRUG DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; RIBONUCLEOTIDE REDUCTASE;

EID: 34247844375     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/01243894-200602000-00006     Document Type: Article
Times cited : (14)

References (32)
  • 1
    • 0033559933 scopus 로고    scopus 로고
    • Estimates of the worldwide incidence of twenty-five major cancers in 1990
    • Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of twenty-five major cancers in 1990. Int J Cancer 1999;80:827-841.
    • (1999) Int J Cancer , vol.80 , pp. 827-841
    • Parkin, D.M.1    Pisani, P.2    Ferlay, J.3
  • 2
    • 0032843811 scopus 로고    scopus 로고
    • Estimates of the worldwide mortality from twenty-five major cancers in 1990
    • Pisani P, Parkin DM, Bray FI, et al. Estimates of the worldwide mortality from twenty-five major cancers in 1990. Int J Cancer 1999;83:18-29.
    • (1999) Int J Cancer , vol.83 , pp. 18-29
    • Pisani, P.1    Parkin, D.M.2    Bray, F.I.3
  • 3
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the international system for staging lung cancer
    • Mountain CF. Revisions in the international system for staging lung cancer. Chest 1997;111:1710-1717.
    • (1997) Chest , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 4
    • 0346238665 scopus 로고    scopus 로고
    • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    • The International Adjuvant Lung Cancer Trial Collaborative Group
    • The International Adjuvant Lung Cancer Trial Collaborative Group. Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 2004;350:351-360.
    • (2004) N Engl J Med , vol.350 , pp. 351-360
  • 5
    • 19844364716 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in completely resected non-small-cell lung cancer
    • Pisters KMW, Le Chevalier T. Adjuvant chemotherapy in completely resected non-small-cell lung cancer. J Clin Oncol 2006;23:3270-3278.
    • (2006) J Clin Oncol , vol.23 , pp. 3270-3278
    • Pisters, K.M.W.1    Le Chevalier, T.2
  • 6
    • 0028216204 scopus 로고
    • A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer
    • Roth JA, Fosella F, Komaki R, et al. A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. J Natl Cancer Inst 1994;86:673-680.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 673-680
    • Roth, J.A.1    Fosella, F.2    Komaki, R.3
  • 7
    • 0032429392 scopus 로고    scopus 로고
    • Long-term follow-up of patients enrolled in a randomised trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer
    • Roth JA, Atkinson EN, Fossella F, et al. Long-term follow-up of patients enrolled in a randomised trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. Lung Cancer 1998;21:1-6.
    • (1998) Lung Cancer , vol.21 , pp. 1-6
    • Roth, J.A.1    Atkinson, E.N.2    Fossella, F.3
  • 8
    • 0027957929 scopus 로고
    • A randomized trial comparing preoperative chemotherapy plus surgery with surgery alone in patients with non-small-cell lung cancer
    • Rosell R, Gómez-Codina J, Camps C, et al. A randomized trial comparing preoperative chemotherapy plus surgery with surgery alone in patients with non-small-cell lung cancer. N Engl J Med 1994;330:153-158.
    • (1994) N Engl J Med , vol.330 , pp. 153-158
    • Rosell, R.1    Gómez-Codina, J.2    Camps, C.3
  • 9
    • 0033215250 scopus 로고    scopus 로고
    • Presectional chemotherapy in stage IIIA non-small-cell lung cancer: A 7-year assessment of a randomised controlled trial
    • Rosell R, Gómez-Codina J, Camps C, et al. Presectional chemotherapy in stage IIIA non-small-cell lung cancer: A 7-year assessment of a randomised controlled trial. Lung Cancer 1999;47:7-14.
    • (1999) Lung Cancer , vol.47 , pp. 7-14
    • Rosell, R.1    Gómez-Codina, J.2    Camps, C.3
  • 10
    • 0036139728 scopus 로고    scopus 로고
    • Depierre A, Milleron B, Moro-Sibilot D, et al. Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer. J Clin Oncol 2002;20:247-253.
    • Depierre A, Milleron B, Moro-Sibilot D, et al. Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer. J Clin Oncol 2002;20:247-253.
  • 11
    • 0033941848 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin as induction regimen for patients with biopsy-proven stage IIIA N2 non-small-cell lung cancer: A Phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group (EORTC 08955)
    • van Zandwijk N, Smit EF, Kramer GWP, et al. Gemcitabine and cisplatin as induction regimen for patients with biopsy-proven stage IIIA N2 non-small-cell lung cancer: A Phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group (EORTC 08955). J Clin Oncol 2000;18:2658-2664.
    • (2000) J Clin Oncol , vol.18 , pp. 2658-2664
    • van Zandwijk, N.1    Smit, E.F.2    Kramer, G.W.P.3
  • 12
    • 0035195406 scopus 로고    scopus 로고
    • A phase II study of induction chemotherapy with gemcitabine (G) and cisplatin (P) in locally advanced non-small cell lung cancer: Interim analysis
    • Santo A, Pedersini R, Pasini F, et al. A phase II study of induction chemotherapy with gemcitabine (G) and cisplatin (P) in locally advanced non-small cell lung cancer: Interim analysis. Lung Cancer 2001;34:S15-S20.
    • (2001) Lung Cancer , vol.34
    • Santo, A.1    Pedersini, R.2    Pasini, F.3
  • 13
    • 0036174949 scopus 로고    scopus 로고
    • A 3-week schedule of gemcitabine plus cisplatin as induction chemotherapy for stage III non-small cell lung cancer
    • Migliorino MR, De Marinis F, Nelli F, et al. A 3-week schedule of gemcitabine plus cisplatin as induction chemotherapy for stage III non-small cell lung cancer. Lung Cancer 2002;35:319-327.
    • (2002) Lung Cancer , vol.35 , pp. 319-327
    • Migliorino, M.R.1    De Marinis, F.2    Nelli, F.3
  • 14
    • 0037797249 scopus 로고    scopus 로고
    • Mediastinal lymph node clearance after docetaxel-cisplatin neoadjuvant chemotherapy is prognostic of survival in patients with stage IIIA pN2 non-small-cell lung cancer
    • Betticher DC, Hsu Schmitz SF, Tötsch M, et al. Mediastinal lymph node clearance after docetaxel-cisplatin neoadjuvant chemotherapy is prognostic of survival in patients with stage IIIA pN2 non-small-cell lung cancer. J Clin Oncol 2003;21:1752-1759.
    • (2003) J Clin Oncol , vol.21 , pp. 1752-1759
    • Betticher, D.C.1    Hsu Schmitz, S.F.2    Tötsch, M.3
  • 15
    • 0038002649 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin as induction chemotherapy for patients with unresectable stage IIIA-bulky N2 and stage IIIB nonsmall cell lung carcinoma
    • Cappuzzo F, Selvaggi G, Gregorc V, et al. Gemcitabine and cisplatin as induction chemotherapy for patients with unresectable stage IIIA-bulky N2 and stage IIIB nonsmall cell lung carcinoma. Cancer 2003;98:128-134.
    • (2003) Cancer , vol.98 , pp. 128-134
    • Cappuzzo, F.1    Selvaggi, G.2    Gregorc, V.3
  • 16
    • 0038461095 scopus 로고    scopus 로고
    • Carboplatin and paclitaxel (Taxol) as an induction regimen for patients with biopsy-proven stage IIIA non-small cell lung cancer: An EORTC phase II study (EORTC 08958)
    • O'Brien MER, Splinter T, Smit EF, et al. Carboplatin and paclitaxel (Taxol) as an induction regimen for patients with biopsy-proven stage IIIA non-small cell lung cancer: An EORTC phase II study (EORTC 08958). Eur J Cancer 2003;39:1416-1422.
    • (2003) Eur J Cancer , vol.39 , pp. 1416-1422
    • O'Brien, M.E.R.1    Splinter, T.2    Smit, E.F.3
  • 17
    • 3242803674 scopus 로고    scopus 로고
    • Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: A meta-analysis
    • Delbaldo C, Michiels S, Syz N, et al. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: A meta-analysis. JAMA 2004;292:470-484.
    • (2004) JAMA , vol.292 , pp. 470-484
    • Delbaldo, C.1    Michiels, S.2    Syz, N.3
  • 18
    • 0032766474 scopus 로고    scopus 로고
    • Cisplatin, gemcitabine, and paclitaxel in locally advanced or metastatic non-small cell lung cancer: A phase I-II study
    • Frasci G, Panza N, Comella P, et al. Cisplatin, gemcitabine, and paclitaxel in locally advanced or metastatic non-small cell lung cancer: A phase I-II study. J Clin Oncol 1999;17:2316-2325.
    • (1999) J Clin Oncol , vol.17 , pp. 2316-2325
    • Frasci, G.1    Panza, N.2    Comella, P.3
  • 19
    • 0033559968 scopus 로고    scopus 로고
    • Phase I/II trial of paclitaxel by 1-hour infusion, carboplatin and gemcitabine in the treatment of patients with advanced nonsmall cell lung carcinoma
    • Hainsworth JD, Burris HA III Erland JB, et al. Phase I/II trial of paclitaxel by 1-hour infusion, carboplatin and gemcitabine in the treatment of patients with advanced nonsmall cell lung carcinoma. Cancer 1999;85:1269-1276.
    • (1999) Cancer , vol.85 , pp. 1269-1276
    • Hainsworth, J.D.1    Burris III, H.A.2    Erland, J.B.3
  • 20
    • 0032841678 scopus 로고    scopus 로고
    • Paclitaxel, gemcitabine, and cisplatin in non-resectable non-small-cell lung cancer
    • Sorensen JB, Stenbygaard LE, Dombernowsky P, et al. Paclitaxel, gemcitabine, and cisplatin in non-resectable non-small-cell lung cancer. Ann Oncol 1999;10:1043-1049.
    • (1999) Ann Oncol , vol.10 , pp. 1043-1049
    • Sorensen, J.B.1    Stenbygaard, L.E.2    Dombernowsky, P.3
  • 21
    • 0033817994 scopus 로고    scopus 로고
    • A phase I/II trial of paclitaxel, carboplatin, and gemcitabine in untreated patients with advanced nonsmall cell lung cancer
    • Kelly K, Mikhaeel-Kamel N, Pan Z, et al. A phase I/II trial of paclitaxel, carboplatin, and gemcitabine in untreated patients with advanced nonsmall cell lung cancer. Clin Cancer Res 2000;6:3474-3479.
    • (2000) Clin Cancer Res , vol.6 , pp. 3474-3479
    • Kelly, K.1    Mikhaeel-Kamel, N.2    Pan, Z.3
  • 22
    • 0034671809 scopus 로고    scopus 로고
    • Paclitaxel, cisplatin, and gemcitabine combination chemotherapy within a multidisciplinary therapeutic approach in metastatic nonsmall cell lung carcinoma: A Phase II study
    • Rodriguez J, Cortes J, Emiliano C, et al. Paclitaxel, cisplatin, and gemcitabine combination chemotherapy within a multidisciplinary therapeutic approach in metastatic nonsmall cell lung carcinoma: A Phase II study. Cancer 2000;89:2622-2629.
    • (2000) Cancer , vol.89 , pp. 2622-2629
    • Rodriguez, J.1    Cortes, J.2    Emiliano, C.3
  • 23
    • 10744227654 scopus 로고    scopus 로고
    • Phase II study of gemcitabine-cisplatin-paclitaxel triplet as induction chemotherapy in inoperable, locally-advanced non-small cell lung cancer
    • Cappuzzo F, De Marinis F, Nelli F, et al. Phase II study of gemcitabine-cisplatin-paclitaxel triplet as induction chemotherapy in inoperable, locally-advanced non-small cell lung cancer. Lung Cancer 2003;42:355-361.
    • (2003) Lung Cancer , vol.42 , pp. 355-361
    • Cappuzzo, F.1    De Marinis, F.2    Nelli, F.3
  • 24
    • 0141923858 scopus 로고    scopus 로고
    • Gemcitabine, paclitaxel, and cisplatin as induction chemotherapy for patients with biopsy-proven stage IIIA(N2) nonsmall cell lung carcinoma
    • De Marinis F, Nelli F, Migliorino MR, et al. Gemcitabine, paclitaxel, and cisplatin as induction chemotherapy for patients with biopsy-proven stage IIIA(N2) nonsmall cell lung carcinoma. Cancer 2003;98:1707-1715.
    • (2003) Cancer , vol.98 , pp. 1707-1715
    • De Marinis, F.1    Nelli, F.2    Migliorino, M.R.3
  • 25
    • 0024440650 scopus 로고
    • Carboplatin dosage: Prospective evaluation of a simple formula based on renal function
    • Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: Prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989;7:1748-1756.
    • (1989) J Clin Oncol , vol.7 , pp. 1748-1756
    • Calvert, A.H.1    Newell, D.R.2    Gumbrell, L.A.3
  • 26
    • 0003575142 scopus 로고    scopus 로고
    • National Cancer Institute, version 2, Bethesda, MD: Division of Cancer Treatment and Diagnosis, National Cancer Institute, Available at:, Accessed April 23
    • National Cancer Institute. Common toxicity criteria (version 2). Bethesda, MD: Division of Cancer Treatment and Diagnosis, National Cancer Institute, 1999. Available at: http://ctep.info.nih.gov/ctc3/ctc.htm. Accessed April 23, 2005.
    • (1999) Common toxicity criteria
  • 27
    • 0034020907 scopus 로고    scopus 로고
    • Induction chemotherapy before surgery for early-stage lung cancer: A novel approach - Bimodality Lung Oncology Team
    • Pisters KM, Ginsberg RJ, Giroux DJ, et al. Induction chemotherapy before surgery for early-stage lung cancer: A novel approach - Bimodality Lung Oncology Team. J Thorac Cardiovasc Surg 2000;119:429-439.
    • (2000) J Thorac Cardiovasc Surg , vol.119 , pp. 429-439
    • Pisters, K.M.1    Ginsberg, R.J.2    Giroux, D.J.3
  • 28
    • 34547395654 scopus 로고    scopus 로고
    • Pisters K, Vallieres E, Bunn P, et al. S990: A phase III trial of surgery alone or surgery plus preoperative (preop) paclitaxel/carboplatin (PC) chemotherapy in early stage non-small cell lung cancer (NSCLC): Preliminary results (Abstract). Proc Am Soc Clin Oncol 2006;23:LBA7012.
    • Pisters K, Vallieres E, Bunn P, et al. S990: A phase III trial of surgery alone or surgery plus preoperative (preop) paclitaxel/carboplatin (PC) chemotherapy in early stage non-small cell lung cancer (NSCLC): Preliminary results (Abstract). Proc Am Soc Clin Oncol 2006;23:LBA7012.
  • 29
    • 5444235920 scopus 로고    scopus 로고
    • Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small-cell lung cancer
    • Hotta K, Matsuo K, Ueoka H, et al. Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small-cell lung cancer. J Clin Oncol 2004;22:3852-3859.
    • (2004) J Clin Oncol , vol.22 , pp. 3852-3859
    • Hotta, K.1    Matsuo, K.2    Ueoka, H.3
  • 30
    • 1342268525 scopus 로고    scopus 로고
    • American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: Update 2003
    • Pfister DG, Johnson DH, Azzoli CG, et al. American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: Update 2003. J Clin Oncol 2004;22:330-353.
    • (2004) J Clin Oncol , vol.22 , pp. 330-353
    • Pfister, D.G.1    Johnson, D.H.2    Azzoli, C.G.3
  • 31
    • 0032947768 scopus 로고    scopus 로고
    • Review of comparative pharmacology and clinical activity of cisplatin and carboplatin
    • Go RS, Adjei AA. Review of comparative pharmacology and clinical activity of cisplatin and carboplatin. J Clin Oncol 1999;17:409-422.
    • (1999) J Clin Oncol , vol.17 , pp. 409-422
    • Go, R.S.1    Adjei, A.A.2
  • 32
    • 0042661285 scopus 로고    scopus 로고
    • Gemcitabine plus cisplatin vs. gemcitabine plus carboplatin in stage IIIb and IV non-small cell lung cancer: A phase III randomized trial
    • Zatloukal P, Petruzělka L, Zemanova M, et al. Gemcitabine plus cisplatin vs. gemcitabine plus carboplatin in stage IIIb and IV non-small cell lung cancer: A phase III randomized trial. Lung Cancer 2003;41:321-331.
    • (2003) Lung Cancer , vol.41 , pp. 321-331
    • Zatloukal, P.1    Petruzělka, L.2    Zemanova, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.