Physical exercise and endothelial progenitor cells

Journal of Cardiopulmonary Rehabilitation and Prevention

Volumn 27, Issue 2, 2007, Pages 74-75

  Custodis, Florian ^b   Laufs, Ulrich ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; VASCULOTROPIN RECEPTOR 2;

ARTERY DISEASE; CARDIOVASCULAR RISK; COLONY FORMING UNIT; CORONARY ARTERY DISEASE; DIABETES MELLITUS; EDITORIAL; ENDOTHELIUM CELL; EXERCISE; HEART FAILURE; HEART REHABILITATION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; LIFESTYLE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RUNNING; STEM CELL MOBILIZATION;

CORONARY ARTERIOSCLEROSIS; ENDOTHELIUM, VASCULAR; EXERCISE; HUMANS; MOTOR ACTIVITY; NITRIC OXIDE; PHYSICAL ENDURANCE; STEM CELLS;

EID: 34247639021     PISSN: 19327501     EISSN: 1932751X     Source Type: Journal    
DOI: 10.1097/01.HCR.0000265032.04307.34     Document Type: Editorial

References (17)

1. Dimmeler S, Aicher A, Vasa M, et al. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest. 2001;108:391-397.
2. Aicher A, Heeschen C, Mildner-Rihm C, et al. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med. 2003;9:1370-1376.
3. Werner N, Junk S, Laufs U, et al. Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res. 2003;93:e17-e24.
4. Werner N, Priller J, Laufs U, et al. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol. 2002;22:1567-1572.
5. Adams V, Lenk K, Linke A, et al. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler Thromb Vasc Biol. 2004;24:684-690.
6. Laufs U, Werner N, Link A, et al. Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis. Circulation. 2004;109:220-226.
7. Werner N, Kosiol S, Schiegl T, et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med. 2005;353:999-1007.
8. Belardinelli R, Paolini I, Cianci G, Piva R, Georgiou D, Purcaro A. Exercise training intervention after coronary angioplasty: the ETICA trial. J Am Coll Cardiol. 2001;37:1891-1900.
9. Hambrecht R, Walther C, Mobius-Winkler S, et al. Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: a randomized trial. Circulation. 2004;109:1371-1378.
10. Endres M, Gertz K, Lindauer U, et al. Mechanisms of stroke protection by physical activity. Ann Neurol. 2003;54:582-590.
11. Hambrecht R, Fiehn E, Weigl C, et al. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation. 1998;98:2709-2715.
12. Stewart KJ, Hiatt WR, Regensteiner JG, Hirsch AT. Exercise training for claudication. N Engl J Med. 2002;347:1941-1951.
13. Vasa M, Fichtlscherer S, Aicher A, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res. 2001;89:E1-E7.
14. Rehman J, Li J, Parvathaneni L, et al. Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells. J Am Coll Cardiol. 2004;43:2314-2318.
15. Laufs U, Urhausen A, Werner N, et al. Running exercise of different duration and intensity: effect on endothelial progenitor cells in healthy subjects. Eur J Cardiovasc Prev Rehabil. 2005;12:407-414.
16. Laufs U, Wassmann S, Czech T, et al. Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis. Arterioscler Thromb Vasc Biol. 2005;25:809-814.
17. Badorff C, Brandes RP, Popp R, et al. Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes. Circulation. 2003;107:1024-1032.