LC-MS for identification and elucidation of the structure of in-vivo and in-vitro metabolites of atropine

Chromatographia

Volumn 65, Issue 7-8, 2007, Pages 413-418

  Chen, H X ^a   Chen, Y ^a   Du, P ^a   Han, F M ^a  

^a HUBEI UNIVERSITY   (China)

Author keywords

Atropine and its in vivo and in vitro metabolites; Column liquid chromatography; MSn detection; Rat feces, urine, plasma, liver homogenate, and intestinal flora

Indexed keywords

ACETIC ACID ETHYL ESTER; ACID; AMMONIUM ACETATE; APOATROPINE; APONORATROPINE; ATROPINE; DIMETHOXYATROPINE; DRUG METABOLITE; FORMIC ACID; METHANOL; METHOXYATROPINE; NORATROPINE; NORTROPINE; TRIMETHOXYATROPINE; TROPINE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD ANALYSIS; COLUMN CHROMATOGRAPHY; DRUG STRUCTURE; FECES ANALYSIS; HYDROLYSIS; INCUBATION TIME; INTESTINE FLORA; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; LIVER; MASS SPECTROMETRY; METABOLISM; METABOLITE; MOLECULAR WEIGHT; PH MEASUREMENT; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; STRUCTURE ANALYSIS; URINALYSIS;

EID: 34247632155     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-007-0187-9     Document Type: Article

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