A simple non-invasive method to detect and monitor hypercapnia: The sodium [13C]bicarbonate breath test

Isotopes in Environmental and Health Studies

Volumn 43, Issue 1, 2007, Pages 23-29

  Modak, Anil S ^a   Reid, Jennie M ^a   Williams, Lori A ^b   Hobbs, Gerald R ^b  

^a CAMBRIDGE ISOTOPE LABORATORIES INC   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

13CO2kinetics; Breath test; Carbon 13; Men; Pulmonary disease

Indexed keywords

BICARBONATE; CARBON; CARBON DIOXIDE;

BLOOD; CARBON DIOXIDE; RESPIRATORY DISEASE;

AGED; ARTICLE; BLOOD; BLOOD PRESSURE; BREATH ANALYSIS; EVALUATION; FEMALE; HUMAN; HYPERCAPNIA; MALE; METHODOLOGY; MIDDLE AGED; PRESSURE; SENSITIVITY AND SPECIFICITY;

AGED; BLOOD PRESSURE; BREATH TESTS; CARBON DIOXIDE; CARBON ISOTOPES; FEMALE; HUMANS; HYPERCAPNIA; MALE; MIDDLE AGED; PARTIAL PRESSURE; SENSITIVITY AND SPECIFICITY; SODIUM BICARBONATE;

EID: 34247624566     PISSN: 10256016     EISSN: 14772639     Source Type: Journal    
DOI: 10.1080/10256010600990849     Document Type: Article

References (25)

1. Hoo, G. Soo, Hakimian, N. and Santiago, S. (2000) Hypercapnic respiratory failure in COPD patients. Chest, 117, pp. 169-177.
2. 2. Br. J. Anaesth., 78, pp. 536-540.
3. 13C breath tests: Transition from research to clinical practice. Breath Analysis For Clinical Diagnosis and Therapeutic Monitoring, pp. 457-478. World Scientific, Singapore
4. 13C] urea breath test. Lancet, 345, pp. 961-962.
5. 13C] uracil breath test. Clin. Can. Res., 10, pp. 2652-2658.
6. 13C] phenylalanine breath test. Chem. Pharm. Bull. (Tokyo), 46, pp. 1330-1332.
7. 13C] methionine breath test. Scand. J. Gastroenterol., 35, pp. 650-653.
8. 2 breath test. Med. Sci. Sports Exerc., 33, pp. 834-838.
9. El-Khoury, A., Sánchez, M., Fukagawa, N., Gleason, R., Tsay, R. and Young, V. (1995) Similar 24 h pattern and rate of carbon dioxide production, by indirect calorimetry vs. stable isotope dilution, in healthy adults under standardized metabolic conditions. J. Nutr., 124, pp. 1615-1627.
10. 13C] bicarbonate tracer technique to measure neonatal energy expenditure. Pediatr. Res., 47, pp. 787-791.
11. 2 breath test. Med. Sci. Sports Exerc., 29, pp. 1263-1268.
12. (2005)
13. 2. Eur. Respir. J, 24, p. 2081. ERS Congress Glasgow, Scotland
14. American Thoracic Society (1995) Standardization of spirometry, 1994 update. Am. J. Respir. Crit. Care Med., 152:3, pp. 1107-1136.
15. 2 breath analyzer: UBiT-IR300 infrared spectrophotometer instruction manual.Meretek Diagnostics, Inc, Lafayette, CO
16. 13C] breath tests to measure fat and carbohydrate digestion in clinical practice. Clin. Nutr., 14, pp. 149-154.
17. O'Donoghue, F., Catcheside, P., Ellis, E., Grunstein, R., Pierce, R., Rowland, L. and Collins, E. (2003) Sleep hypoventilation in hypercapnic chronic obstructive pulmonary disease: Prevalence and associated factors. Eur. Respir. J., 21, pp. 977-984.
18. Vitacca, M. (2001) Exacerbations of COPD: Predictive factors, treatment and outcome. Monaldi Arch. Chest Dis., 56, pp. 137-143.
19. Begin, P. and Grassino, A. (1991) Inspiratory muscle dysfunction and chronic hypercapnia in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis., 143, pp. 905-912.
20. Abou-Shala, N. and Meduri, U. (1996) Noninvasive mechanical ventilation in patients with acute respiratory failure. Crit. Care Med., 24, pp. 705-715.
21. 2 production. Am. J. Physiol. Endocrinol. Metab., 268:6, pp. E1123-E1127.
22. 13C] bicarbonate. Med. Sci. Res., 25, pp. 9-10.
23. 2 kinetics in humans after oral application of sodium bicarbonate as a model for breath testing. Eur. J. Clin. Invest., 23:2, pp. 91-96.
24. 13C] bicarbonate kinetics in humans: Intra- vs. interindividual variations. Am. J. Physiol., 245, pp. R190-R202.
25. Pauwels, R., Buist, A., Ma, P., Jenkins, C. and Hurd, S. (2001) GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): Executive summary. Respir. Care, 46, pp. 798-825.