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Volumn 96, Issue 9, 2007, Pages 1353-1357

Phase-I trial of oral fluoropyrimidine anticancer agent (S-1) with concurrent radiotherapy in patients with unresectable pancreatic cancer

Author keywords

Chemoradiation; Pancreatic cancer; Phase I study; S 1

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR;

EID: 34247617372     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603735     Document Type: Article
Times cited : (20)

References (33)
  • 5
    • 0019410935 scopus 로고
    • Therapy of locally unresectable pancreatic carcinoma: A randomised comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads+5-fluorouracil), and high dose radiation+5-fluorouracil
    • Gastrointestinal Tumour Study Group
    • Gastrointestinal Tumour Study Group (1981) Therapy of locally unresectable pancreatic carcinoma: a randomised comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads+5-fluorouracil), and high dose radiation+5-fluorouracil. Cancer 48: 1705-1710
    • (1981) Cancer , vol.48 , pp. 1705-1710
  • 6
    • 0023722682 scopus 로고
    • Treatment of locally unresectable carcinoma of the pancreas: Comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone
    • Gastrointestinal Tumour Study Group
    • Gastrointestinal Tumour Study Group (1988) Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. J Natl Cancer Inst 80: 751-755
    • (1988) J Natl Cancer Inst , vol.80 , pp. 751-755
  • 7
    • 2542506412 scopus 로고    scopus 로고
    • Harada K, Kawaguchi S, Supriatno , Onoue T, Yoshida H, Sato M (2004) Combined effects of the oral fluoropyrimidine anticancer agent, S-1 and radiation on human oral cancer cells. Oral Oncol 40: 713-719
    • Harada K, Kawaguchi S, Supriatno , Onoue T, Yoshida H, Sato M (2004) Combined effects of the oral fluoropyrimidine anticancer agent, S-1 and radiation on human oral cancer cells. Oral Oncol 40: 713-719
  • 10
  • 11
    • 0035964611 scopus 로고    scopus 로고
    • Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer
    • S-1 Cooperative Study Group Lung Cancer Working Group
    • Kawahara M, Furuse K, Segawa Y, Yoshimori K, Matsui K, Kudoh S, Hasegawa K, Niitani H, S-1 Cooperative Study Group (Lung Cancer Working Group) (2001) Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer. Br J Cancer 85: 939-943
    • (2001) Br J Cancer , vol.85 , pp. 939-943
    • Kawahara, M.1    Furuse, K.2    Segawa, Y.3    Yoshimori, K.4    Matsui, K.5    Kudoh, S.6    Hasegawa, K.7    Niitani, H.8
  • 12
    • 0021918519 scopus 로고
    • Treatment of locally unresectable cancer of the stomach and pancreas: A randomised comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil - an Eastern Cooperative Oncology Group study
    • Klaassen DJ, MacIntyre JM, Catton GE, Engstrom PF, Moertel CG (1985) Treatment of locally unresectable cancer of the stomach and pancreas: a randomised comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil - an Eastern Cooperative Oncology Group study. J Clin Oncol 3: 373-378
    • (1985) J Clin Oncol , vol.3 , pp. 373-378
    • Klaassen, D.J.1    MacIntyre, J.M.2    Catton, G.E.3    Engstrom, P.F.4    Moertel, C.G.5
  • 13
    • 0034029776 scopus 로고    scopus 로고
    • Phase II study of S-1, a novel oral derivative of 5-fluorouracil, in advanced gastric cancer. For the S-1 Cooperative Gastric Cancer Study Group
    • Koizumi W, Kurihara M, Nakano S, Hasegawa K (2000) Phase II study of S-1, a novel oral derivative of 5-fluorouracil, in advanced gastric cancer. For the S-1 Cooperative Gastric Cancer Study Group. Oncology 58: 191-197
    • (2000) Oncology , vol.58 , pp. 191-197
    • Koizumi, W.1    Kurihara, M.2    Nakano, S.3    Hasegawa, K.4
  • 15
    • 0038460691 scopus 로고    scopus 로고
    • Radiation therapy with once-weekly gemcitabine in pancreatic cancer: Current status of clinical trials
    • McGinn CJ, Zalupski MM (2003) Radiation therapy with once-weekly gemcitabine in pancreatic cancer: current status of clinical trials. Int J Radiat Oncol Biol Phys 56(4 Suppl): 10-15
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , Issue.4 SUPPL. , pp. 10-15
    • McGinn, C.J.1    Zalupski, M.M.2
  • 17
    • 0014691062 scopus 로고
    • Combined 5-fluorouracil and supervoltage radiation therapy of locally unresectable gastrointestinal cancer
    • Moertel CG, Childs Jr DS, Reitemeier RJ, Colby Jr MY, Holbrook MA (1969) Combined 5-fluorouracil and supervoltage radiation therapy of locally unresectable gastrointestinal cancer. Lancet 2: 865-867
    • (1969) Lancet , vol.2 , pp. 865-867
    • Moertel, C.G.1    Childs Jr, D.S.2    Reitemeier, R.J.3    Colby Jr, M.Y.4    Holbrook, M.A.5
  • 18
    • 33745258389 scopus 로고    scopus 로고
    • Phase II trial of oral S-1 combined with gemcitabine in metastatic pancreatic cancer
    • Nakamura K, Yamaguchi T, Ishihara T, Sudo K, Kato H, Saisho H (2006) Phase II trial of oral S-1 combined with gemcitabine in metastatic pancreatic cancer. Br J Cancer 94: 1575-1579
    • (2006) Br J Cancer , vol.94 , pp. 1575-1579
    • Nakamura, K.1    Yamaguchi, T.2    Ishihara, T.3    Sudo, K.4    Kato, H.5    Saisho, H.6
  • 19
    • 0028799366 scopus 로고
    • The National Cancer Data Base report on pancreatic cancer
    • Niederhuber JE, Brennan MF, Menck HR (1995) The National Cancer Data Base report on pancreatic cancer. Cancer 76: 1671-1677
    • (1995) Cancer , vol.76 , pp. 1671-1677
    • Niederhuber, J.E.1    Brennan, M.F.2    Menck, H.R.3
  • 20
    • 0034089123 scopus 로고    scopus 로고
    • Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group
    • Ohtsu A, Baba H, Sakata Y, Mitachi Y, Horikoshi N, Sugimachi K, Taguchi T (2000) Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group. Br J Cancer 83: 141-145
    • (2000) Br J Cancer , vol.83 , pp. 141-145
    • Ohtsu, A.1    Baba, H.2    Sakata, Y.3    Mitachi, Y.4    Horikoshi, N.5    Sugimachi, K.6    Taguchi, T.7
  • 22
    • 0034076905 scopus 로고    scopus 로고
    • Unresectable adenocarcinoma of the pancreas: Patterns of failure and treatment results
    • Paulino AC, Latona C (2000) Unresectable adenocarcinoma of the pancreas: patterns of failure and treatment results. Cancer Invest 18: 309-313
    • (2000) Cancer Invest , vol.18 , pp. 309-313
    • Paulino, A.C.1    Latona, C.2
  • 23
    • 0033056887 scopus 로고    scopus 로고
    • Chemoradiotherapy in the management of localized tumours of the pancreas
    • Poen JC, Ford JM, Niederhuber JE (1999) Chemoradiotherapy in the management of localized tumours of the pancreas. Ann Surg Oncol 6: 117-122
    • (1999) Ann Surg Oncol , vol.6 , pp. 117-122
    • Poen, J.C.1    Ford, J.M.2    Niederhuber, J.E.3
  • 24
    • 1542269125 scopus 로고    scopus 로고
    • The modulated oral fluoropyrimidine prodrug S-1, and its use in gastrointestinal cancer and other solid tumours
    • Schoffski P (2004) The modulated oral fluoropyrimidine prodrug S-1, and its use in gastrointestinal cancer and other solid tumours. Anticancer Drugs 15: 85-106
    • (2004) Anticancer Drugs , vol.15 , pp. 85-106
    • Schoffski, P.1
  • 25
    • 0036569654 scopus 로고    scopus 로고
    • Length and quality of survival after external-beam radiotherapy with concurrent continuous 5-fluorouracil infusion for locally unresectable pancreatic cancer
    • Shinchi H, Takao S, Noma H, Matsuo Y, Mataki Y, Mori S, Aikou T (2002) Length and quality of survival after external-beam radiotherapy with concurrent continuous 5-fluorouracil infusion for locally unresectable pancreatic cancer. Int J Radiat Oncol Biol Phys 53: 146-150
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 146-150
    • Shinchi, H.1    Takao, S.2    Noma, H.3    Matsuo, Y.4    Mataki, Y.5    Mori, S.6    Aikou, T.7
  • 26
    • 0027227591 scopus 로고
    • Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumour activity in rats
    • Shirasaka T, Shimamoto Y, Fukushima M (1993) Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumour activity in rats. Cancer Res 53: 4004-4009
    • (1993) Cancer Res , vol.53 , pp. 4004-4009
    • Shirasaka, T.1    Shimamoto, Y.2    Fukushima, M.3
  • 27
    • 0029835349 scopus 로고    scopus 로고
    • Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumour selective cytotoxicity of 5-fluorouracil by two biochemical modulators
    • Shirasaka T, Shimamato Y, Ohshimo H, Yamaguchi M, Kato T, Yonekura K, Fukushima M (1996) Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumour selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 7: 548-557
    • (1996) Anticancer Drugs , vol.7 , pp. 548-557
    • Shirasaka, T.1    Shimamato, Y.2    Ohshimo, H.3    Yamaguchi, M.4    Kato, T.5    Yonekura, K.6    Fukushima, M.7
  • 29
    • 23844431643 scopus 로고    scopus 로고
    • An early phase II study of S-1 in patients with metastatic pancreatic cancer
    • Ueno H, Okusaka T, Ikeda M, Takezako Y, Morizane C (2005) An early phase II study of S-1 in patients with metastatic pancreatic cancer. Oncology 68: 171-178
    • (2005) Oncology , vol.68 , pp. 171-178
    • Ueno, H.1    Okusaka, T.2    Ikeda, M.3    Takezako, Y.4    Morizane, C.5
  • 31
    • 0028874278 scopus 로고
    • Protracted intravenous fluorouracil infusion with radiation therapy in the management of localized pancreaticobiliary carcinoma: A phase I Eastern Cooperative Oncology Group Trial
    • Whittington R, Neuberg D, Tester WJ, Benson III AB, Haller DG (1995) Protracted intravenous fluorouracil infusion with radiation therapy in the management of localized pancreaticobiliary carcinoma: a phase I Eastern Cooperative Oncology Group Trial. J Clin Oncol 13: 227-232
    • (1995) J Clin Oncol , vol.13 , pp. 227-232
    • Whittington, R.1    Neuberg, D.2    Tester, W.J.3    Benson III, A.B.4    Haller, D.G.5
  • 32
    • 0001522421 scopus 로고
    • WHO handbook for reporting results of cancer treatment
    • WHO World Health Organization
    • WHO (World Health Organization) (1980) WHO handbook for reporting results of cancer treatment. Neoplasma 27: 607-619
    • (1980) Neoplasma , vol.27 , pp. 607-619


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