Ventricular ectopy during REM sleep: Implications for nocturnal sudden cardiac death

Nature Clinical Practice Cardiovascular Medicine

Volumn 4, Issue 5, 2007, Pages 284-288

  Garcia Touchard, Arturo ^a,c   Somers, Virend K ^a   Kara, Tomas ^a,d   Nykodym, Jiri ^b   Shamsuzzaman, Abu ^a   Lanfranchi, Paola ^e   Ackerman, Michael J ^b  

^a Mayo Clinic   (United States)

^b MAYO CLINIC   (United States)

^c HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^d International Clinical Research Center   (Czech Republic)

^e HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; METHIONINE; MEXILETINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNJ2; THREONINE; UNCLASSIFIED DRUG; ANTIARRHYTHMIC AGENT;

ADOLESCENT; AMINO ACID SUBSTITUTION; ANDERSEN SYNDROME; ARRHYTHMOGENESIS; ARTICLE; CARDIAC CHANNELOPATHY; CASE REPORT; CLINICAL FEATURE; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA SEQUENCE; ELECTROMYOGRAPHY; EXERCISE TEST; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HEART VENTRICLE CONTRACTION; HEART VENTRICLE TACHYCARDIA; HOLTER MONITORING; HUMAN; MUSCLE BIOPSY; MUSCLE WEAKNESS; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REM SLEEP; SUDDEN DEATH; SYNCOPE; BIOPSY; DIFFERENTIAL DIAGNOSIS; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FOLLOW UP; HEART VENTRICLE EXTRASYSTOLE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SKELETAL MUSCLE;

ADOLESCENT; ANTI-ARRHYTHMIA AGENTS; BIOPSY; DEATH, SUDDEN, CARDIAC; DIAGNOSIS, DIFFERENTIAL; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY, AMBULATORY; ELECTROMYOGRAPHY; EXERCISE TEST; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MEXILETINE; MUSCLE, SKELETAL; POLYSOMNOGRAPHY; SLEEP, REM; VENTRICULAR PREMATURE COMPLEXES;

EID: 34247616826     PISSN: 17434297     EISSN: 17434300     Source Type: Journal    
DOI: 10.1038/ncpcardio0877     Document Type: Article

References (15)

1. Sansone V et al. (1997) Andersen's syndrome: A distinct periodic paralysis. Ann Neurol 42: 305-312
2. Plaster NM et al. (2001) Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. Cell 105: 511-519
3. Ai T et al. (2002) Novel KCNJ2 mutation in familial periodic paralysis with ventricular dysrhythmia. Circulation 105: 2592-2594
4. Zhang L et al. (2005) Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations: characteristic T-U-wave patterns predict the KCNJ2 genotype. Circulation 111: 2720-2726
5. Tsuboi M and Antzelevitch C (2006) Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7). Heart Rhythm 3: 328-335
6. Ackerman MJ (2004) Cardiac channelopathies: It's in the genes. Nat Med 10: 463-464
7. Somers VK et al. (1993) Sympathetic-nerve activity during sleep in normal subjects. N Engl J Med 328: 303-307
8. Verrier RL et al. (1996) Sleep, dreams, and sudden death: The case for sleep as an autonomic stress test for the heart. Cardiovasc Res 31: 181-211
9. Manning JM and Cotten MD (1962) Mechanism of cardiac arrhythmias induced by diencephalic stimulation. Am J Physiol 203: 1120-1124
10. Zareba W et al. (1998) Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group. N Engl J Med 339: 960-965
11. Schwartz PJ et al. (2001) Genotype - phenotype correlation in the long-QT syndrome: Gene-specific triggers for life-threatening arrhythmias. Circulation 103: 89-95
12. Verrier RL et al. Noninvasive sudden death risk stratification by ambulatory ECG-based T-wave alternans analysis: Evidence and methodological guidelines. Ann Noninvasive Electrocardiol 10 110-120
13. Krittayaphong R et al. (2003) Heart rate variability in patients with Brugada syndrome in Thailand. Eur Heart J 24: 1771-1778
14. Schwartz PJ (2005) Management of long QT syndrome. Nat Clin Pract Cardiovasc Med 2: 346-351
15. Pouget J and Serratrice G (1983) Myotonia with muscular weakness corrected by exercise: The therapeutic effect of mexiletine [French]. Rev Neurol (Paris) 139: 665-672