Peptidomimics of antigen are present in variable region of heavy and light chains of anti-idiotypic antibody and function as surrogate antigen for perpetuation of immunological memory

Molecular Immunology

Volumn 44, Issue 13, 2007, Pages 3345-3354

  Vani, J ^a   Justin, Jayakani ^a   Nagasuma, R Chandra ^a   Nayak, Rabindranath ^a   Shaila, M S ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Anti idiotypic B cells; Idiopeptides; Immunological memory; Peptidomimics; Relay hypothesis

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; EPITOPE; GAMMA INTERFERON; IMMUNOGLOBULIN; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS HEMAGGLUTININ;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CATTLE PLAGUE VIRUS; COMPUTER MODEL; CONTROLLED STUDY; FEMALE; GENE SEQUENCE; HEAVY CHAIN; IMMUNIZATION; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGICAL MEMORY; IMMUNOSTIMULATION; LIGHT CHAIN; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGENS; CELL LINE, TUMOR; EPITOPE MAPPING; FEMALE; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGIC MEMORY; MICE; MICE, INBRED BALB C; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PEPTIDES;

RINDERPEST VIRUS;

EID: 34247604567     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.02.015     Document Type: Article

References (47)

1. Arnon R., and Howitz R.J. Synthetic peptides as vaccines. Curr. Opin. Immunol. 4 (1992) 449-453
2. Beeley N. Peptidomimetics and small-molecule drug design: towards improved bioavailability and in vivo stability. Trends Biotechnol. 12 (1994) 213-216
3. Berman H.M., Westbrook J., Feng Z., Gilliland G., Bhat T.N., Weissig H., Shindyalov I.N., and Bourne P.E. The protein data bank. Nucl. Acids Res. 28 (2000) 235-242
4. Brown F. New approaches to vaccination against foot-and-mouth disease. Vaccine 10 (1992) 1022-1026
5. Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse-Kunstleve R.W., Jiang J.S., Kuszewski J., Nilges M., Pannu N.S., Read R.J., Rice L.M., Simonson T., and Warren G.L. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. 54D (1998) 905-921
6. Chakrabarti D., and Ghosh S.K. Induction of syngeneic cytotoxic T lymphocytes against a B cell tumor. III. MHC class I-restricted CTL recognizes the processed form(s) of idiotype. Cell. Immunol. 144 (1992) 455-464
7. Claverie J.M., and Kourilsky P. The peptidic self model: a reassessment of the role of the major histocompatibility complex molecules in the restriction of the T-cell response. Ann. Immunol. (Inst. Pasteur) 137D3 (1986) 425-442
8. Dabadghao S., Bergenbrant S., Anton D., He W., Holm G., and Yi Q. Anti-idiotypic T-cell activation in multiple myeloma induced by M-component fragments presented by dendritic cells. Br. J. Haematol. 100 (1998) 647-654
9. Durrant L.G., Buckley D.J., Robins R.A., and Spendlove I. 105Ad7 cancer vaccine stimulates anti-tumor helper and cytotoxic T-cell responses in colorectal cancer patients but repeated immunizations are required to maintain these responses. Int. J. Cancer. 85 (2000) 87-92
10. Gante J. Peptidomimetics-tailored enzyme inhibitors. Angew. Chem. Int. Ed. Engl. 33 (1994) 1699-1720
11. Gonser S., Weber E., and Folkers G. Peptides and polypeptides as modulators of the immune response: thymopentin-an example with unknown mode of action. Pharm. Acta Helv. 73 (1999) 265-273 (Review)
12. Greenspan N.S., and Bona C.A. Idiotypes: structure and immunogenicity. FASEB J. 7 (1993) 437-444 (Review)
13. Hardy B., and Raiter A. A mimotope peptide-based anti-cancer vaccine selected by BAT monoclonal antibody. Vaccine 23 (2005) 4283-4291
14. Harada K., and Ikegami T. Evolution of specificity in an immune network. J. Theor. Biol. 203 (2000) 439-449
15. Hansson L., Rabbani H., Fagerberg J., Sterborg A.O., and Mellstedt H. T-cell epitopes within the complementarity-determining and framework regions of the tumor-derived immunoglobulin heavy chain in multiple myeloma. Blood 101 (2003) 4930-4936
16. Jain D., Kaur K.J., Sundaravadivel B., and Salunke D.M. Structural and functional consequences of peptide-carbohydrate mimicry. J. Biol. Chem. 275 (2000) 16098-16102
17. Jerne N.K. Towards a network theory of the immune system. Ann. Immunol. (Paris) 125c (1974) 373-389
18. Kaur K.J., Jain D., Goel M., and Salunke D.M. Immunological implications of structural mimicry between a dodecapeptide and a carbohydrate moiety. Vaccine 19 (2001) 3124-3130
19. Kourilsky P., Chaouat G., Rabourdin-Combe C., and Claverie J.M. Working principles in the immune system implied by the "peptidic self" model. Proc. Natl. Acad. Sci. USA 84 (1987) 3400-3404
20. Kourilsky P., and Claverie J.M. The peptidic self model: a hypothesis on the molecular nature of the immunological self. Ann. Immunol. (Inst. Pasteur) 137D (1986) 3-21
21. Lal G., Shaila M.S., and Nayak R. Booster immunization of antigen primed mice with anti-idiotypic T cells generates antigen-specific memory T cell response. Vaccine 24 (2006) 1149-1158
22. Mitra-Kaushik S., Shaila M.S., Karande A.K., and Nayak R. Idiotype and antigen-specific T cell responses in mice on immunization with antigen, antibody, and anti-idiotypic antibody. Cell. Immunol. 209 (2001) 109-119
23. Mitra-Kaushik S., Shaila M.S., Karande A., and Nayak R. Idiotype and anti-idiotype specific T cell responses on transplantation with hybridomas reactive to viral hemagglutinin and human tumor antigen. Immunol. Lett. 80 (2002) 81-87
24. Moe G.R., Tan S., and Granoff D.M. Molecular mimetics of polysaccharide epitopes as vaccine candidates for prevention of Neisseria meningitidis serogroup B disease. FEMS Immunol. Med. Microbiol. 26 (1999) 209-226
25. Naik S., and Shaila M.S. Characterization of membrane-bound and membrane anchor-less forms of hemagglutinin glycoprotein of Rinderpest virus expressed by baculovirus recombinants. Virus Genes 14 (1997) 95-104
26. Nayak R., Mitra-Kaushik S., and Shaila M.S. Perpetuation of immunological memory: a relay hypothesis. Immunology 102 (2001) 387-395
27. Neumann A.U., and Weisbuch G. Dynamics and topology of idiotypic networks. Bull. Math. Biol. 54 (1992) 699-726
28. Nisonoff A., and Lamoyi E. Implications of the presence of an internal image of the antigen in anti idiotypic antibodies: possible application to vaccine production. Clin. Immunol. Immunopathol. 21 (1981) 397-406
29. Prinz D.M., Smithson S.L., and Westerink M.A. Two different methods result in the selection of peptides that induce a protective antibody response to Neisseria meningitidis serogroup C. J. Immunol. Methods 285 (2004) 1-14
30. Parker K.C., Bednarek M.A., and Coligan J.E. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J. Immunol. 152 (1994) 163-175
31. Pride M.W., Shi H., Anchin J.M., Linthicum D.S., LoVerde P.T., Thakur A., and Thanavala Y. Molecular mimicry of hepatitis B surface antigen by an anti-idiotype-derived synthetic peptide. Proc. Natl. Acad. Sci. USA 89 (1992) 11900-11904
32. Pride M.W., Shuey S., Grillo-Lopez A., Braslawsky G., Ross M., Legha S.S., Eton O., Buzaid A., Ioannides C., and Murray J.L. Enhancement of cell-mediated immunity in melanoma patients immunized with murine anti-idiotypic monoclonal antibodies (MELIMMUNE) that mimic the high molecular weight proteoglycan antigen. Clin. Cancer Res. 4 (1998) 2363-2370
33. Qabar M., Urban J., Sia C., Klein M., and Kahn M. Peptide secondary structure mimetics: applications to vaccines and pharmaceuticals. Farmaco 51 (1996) 87-96
34. Rammensee H., Bachmann J., Emmerich N.P., Bachor O.A., and Stevanovic S. SYFPEITHI: database for MHC ligands and peptide motifs. Immunogenetics 50 (1999) 213-219 (Review)
35. Roitt I.M., Cooke A., Male D.K., Hay F.C., Guarnotta G., Lydyard P.M., de Carvalho L.P., Thanavala Y., and Ivanyi J. Idiotypic networks and their possible exploitation for manipulation of the immune response. Lancet 9 (1981) 1041-1045
36. Ruiz P.J., Wolkowicz R., Waisman A., Hirschberg D.L., Carmi P., Erez N., Garren H., Herkel J., Karpuj M., Steinman L., Rotter V., and Cohen I.R. Idiotypic immunization induces immunity to mutated p53 and tumor rejection. Nat. Med. 4 (1998) 710-712
37. Sette A., Vitiello A., Reherman B., Fowler P., Nayersina R., Kast W.M., Melief C.J., Oseroff C., Yuan L., Ruppert J., Sidney J., del Guercio M.F., Southwood S., Kubo R.T., Chesnut R.W., Grey H.M., and Chisari F.V. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. J. Immunol. 153 (1994) 5586-5592
38. Sinnathamby G., Renukaradhya G.J., Rajasekhar M., Nayak R., and Shaila M.S. Recombinant hemagglutinin protein of rinderpest virus expressed in insect cells induces cytotoxic T-cell responses in cattle. Viral Immunol. 14 (2001) 349-358
39. Smith T.F., and Waterman M.S. Identification of common molecular subsequences. J. Mol. Biol. 147 (1981) 195-197
40. Townsend A.R., Rothbard J., Gotch F.M., Bahadur G., Wraith D., and McMichael A.J. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44 (1986) 959-968
41. Van der Burg S.H., Visseren M.J., Brandt R.M., Kast W.M., and Melief C.J. Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability. J. Immunol. 156 (1996) 3308-3314
42. Vani J., Nayak R., and Shaila M.S. Maintenance of antigen-specific immunological memory through variable regions of heavy and light chains of anti-idiotypic antibody. Immunology 120 (2007) 486-496
43. Wagner U., Kohler S., Reinartz S., Giffels P., Huober J., Renke K., Schlebusch H., Biersack H.J., Mobus V., Kreienberg R., Bauknecht T., Krebs D., and Wallwiener D. Immunological consolidation of ovarian carcinoma recurrences with monoclonal anti-idiotype antibody ACA125: immune responses and survival in palliative treatment. Clin. Cancer Res. 7 (2001) 1154-1162
44. Westerink M.A.J., Campagnari A.A., Wirth M.A., and Apicella M.A. Development and characterization of an anti-idiotype antibody to the capsular polysaccharide of Neisseria meningitidis serogroup C. Infect. Immun. 56 (1988) 1120-1127
45. Westerink M.A.J., Giardina P.C., Apicella M.A., and Kieber-Emmons T. Peptide mimicry of the meningococcal group C capsular polysaccharide. Proc. Natl. Acad. Sci. USA 92 (1995) 4021-4025
46. Yoshimura Y., Yadav R., Christianson G.J., Ajayi W.U., Roopenian D.C., and Joyce S. Duration of alloantigen presentation and avidity of T cell antigen recognition correlate with immuno dominance of CTL response to minor histocompatibility antigens. J. Immunol. 172 (2004) 6666-6674
47. Zhang W., and Reichlin M. A peptide DNA surrogate that binds and inhibits anti-ds DNA antibodies. Clin. Immunol. 117 (2005) 214-220 (Review)