Synthesis and evaluation of some gastrointestinal sparing anti-inflammatory aminoethyl ester derivatives of naphthalene-based NSAIDs

Archiv der Pharmazie

Volumn 340, Issue 2, 2007, Pages 88-94

  Halen, Parmeshwari K ^a   Raval, Manisha K ^a   Chagti, Kewal K ^a   Giridhar, Rajani ^a   Yadav, Mange R ^a  

^a M S UNIVERSITY OF BARODA   (India)

Author keywords

Anti inflammatory; Gastrointestinal irritation; Naproxen; Rat paw edema; Ulcerogenicity

Indexed keywords

2 (1 PIPERIDINO)ETHYL 2 (6 METHOXY 2 NAPHTHYL) PROPANOATE; 2 (1 PIPERIDINO)ETHYL 6 METHOXY 2 NAPHTHYLACETATE; 2 (1 PYRROLIDINO)ETHYL 2 (6 METHOXY 2 NAPHTHYL) PROPANOATE; 2 (1 PYRROLIDINO)ETHYL 6 METHOXY 2 NAPHTHYLACETATE; 2 (4 MORPHOLINO)ETHYL 2 (6 METHOXY 2 NAPHTHYL) PROPANOATE; 2 (4 MORPHOLINO)ETHYL 6 METHOXY 2 NAPHTHYLACETATE; 2 DIETHYLAMINOETHYL 2 (6 METHOXY 2 NAPHTHYL)PROPANOATE; 2 DIETHYLAMINOETHYL 6 METHOXY 2 NAPHTHYLACETATE; 2 DIMETHYLAMINOETHYL 2 (6 METHOXY 2 NAPHTHYL)PROPANOATE; 2 DIMETHYLAMINOETHYL 6 METHOXY 2 NAPHTHYLACETATE; 6 METHOXY 2 NAPHTHYLACETIC ACID; 8 METHYL 8 AZABICYCLO[3,2,1]OCTAN 3 YL 6 METHOXY 2 NAPHTHYLACETATE; 8 METHYL 8 AZABICYCLO[3.2.1]OCTAN 3YL 2 (6 METHOXY 2 NAPHTHYL)PROPANOATE; ACETYLCHOLINE; NABUMETONE; NAPHTHALENE; NAPROXEN; NAPROXEN DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG; NAPHTHALENE DERIVATIVE;

ANTICHOLINERGIC EFFECT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG POTENCY; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; MALE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT; SERUM; STOMACH ACID SECRETION; STOMACH IRRITATION; ULCEROGENESIS; ANIMAL; BIOAVAILABILITY; DRUG EFFECT; EDEMA; HALF LIFE TIME; INTESTINE ABSORPTION; SECRETION; SPRAGUE DAWLEY RAT; STOMACH ACID; STOMACH MUCOSA; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL AVAILABILITY; EDEMA; FEMALE; GASTRIC ACID; GASTRIC MUCOSA; HALF-LIFE; INTESTINAL ABSORPTION; MALE; NAPHTHALENES; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34247597973     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200600159     Document Type: Article

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