Transactivation of Src, PDGF receptor, and Akt is involved in IL-1β-induced ICAM-1 expression in A549 cells

Journal of Cellular Physiology

Volumn 211, Issue 3, 2007, Pages 771-780

  Lin, Chih Chung ^a   Lee, Chiang Wen ^a   Chu, Tzu Hua ^a   Cheng, Ching Yi ^a   Luo, Shue Fen ^a   Hsiao, Li Der ^a   Yang, Chuen Mao ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; CURCUMIN; HELENALIN; HISTONE H4; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P300; PROTEIN P85; PROTEIN TYROSINE KINASE; WORTMANNIN;

ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLATION; CELL ADHESION; CELL LINE, TUMOR; GENE EXPRESSION; HISTONES; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; LUNG NEOPLASMS; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; NF-KAPPA B; P300-CBP TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RESPIRATORY MUCOSA; RNA, MESSENGER; SRC-FAMILY KINASES; TRANSCRIPTION, GENETIC;

EID: 34247597228     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20987     Document Type: Article

References (45)

1. Ait-Si-Ali S, Carlisi D, Ramirez S, Upegui-Gonzalez LC, Duquet A, Robin P, Rudkin B, Harel-Bellan A, Trouche D. 1999. Phosphorylation by p44 MAP Kinase/ERK1 stimulates CBP histone acetyl-transferase activity in vitro. Biochem Biophys Res Commun 262:157-162.
2. al-Ramadi BK, Welte T, Fernandez-Cabezudo MJ, Galadari S, Dittel B, Fu XY, Bothwell ALM. 2001. The Src-protein tyrosine kinase Lck is required for IL-1-mediated co-stimulatory signaling in Th2 cells. J Immunol 167:6827-6833.
3. Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. 1996. Molecular basis for the substrate specificity of protein kinase B comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett 399:333-338.
4. Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJ, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. 1997. Role of translocation in the activation and function of protein kinase B. J Biol Chem 272:31515-31524.
5. Armstrong EJ, Morrow DA, Sabatine MS. 2006. Inflammatory biomarkers in acute coronary syndromes: Part II: Acute-phase reactants and biomarkers of endothelial cell activation. Circulation 113:e152-e155.
6. Balasubramanyam K, Varier RA, Altaf M, Swaminathan V, Siddappa NB, Ranga U, Kundu TK. 2004. Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 279:51163-51171.
7. Barnes PJ, Adcock IM, Ito K. 2005. Histone acetylation and deacetylation: Importance in inflammatory lung diseases. Eur Respir J 25:552-563.
8. Basit A, Reutershan J, Morris MA, Solga M, Rose J, Ley K. 2006. ICAM-1 and LFA-1 play critical roles in LPS-induced neutrophil recruitment into the alveolar space. Am J Physiol Lung Cell Mol Physiol 291:L200-L207.
9. Bromann PA, Korkaya H, Courtneidge SA. 2004. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 23:7957-7968.
10. 2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem 278:35451-35457.
11. Chan HM, La Thangue NB. 2001. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 114:2363-2373.
12. Chang YJ, Holtzman MJ, Chen CC. 2004. Differential role of Janus family kinases (JAKs) in Interferon-γ-induced lung epithelial ICAM-1 expression: Involving protein interactions between JAKs, Phospholipase Cγ, c-Src, and STAT1. Mol Pharmacol 65:589-598.
13. Chen CC, Chou CY, Sun YT, Huang WC. 2001. Tumor necrosis factor α-induced activation of downstream NF-κB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion: Involvement of PKCα, tyrosine kinase, and IKK2, but not MAPKs pathway. Cell Signal 13:543-553.
14. Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC. 2005. NF-κB RelA phosphorylation regulates RelA acetylation. Mol Cell Biol 25:7966-7975.
15. Dandekar AA, Perlman S. 2005. Immunopathogenesis of coronavirus infections: Implications for SARS. Nat Rev Immunol 5:917-927.
16. Darieva Z, Lasunskaia EB, Campos MNN, Kipnis TL, da Silva WD. 2004. Activation of phosphatidylinositol 3-kinase and c-Jun-N-terminal kinase cascades enhances NF-κB-dependent gene transcription in BCG-stimulated macrophages through promotion of p65/p300 binding. J Leukoc Biol 75:689-697.
17. Datta SR, Brunet A, Greenberg ME. 1999. Cellular survival: A play in three Akts. Genes Dev 13:2905-2927.
18. Deng WG, Zhu Y, Wu KK. 2003. Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-α-induced cyclooxygenase-2 promoter activation. J Biol Chem 278:4770-4777.
19. Downward J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10:262-267.
20. Goodman RH, Smolik S. 2000. CBP/p300 in cell growth, transformation, and development. Genes Dev 14:1553-1577.
21. Heldin CH, Westermark B. 1999. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79:1283-1316.
22. Huang WC, Chen CC. 2005. Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. Mol Cell Biol 25:6592-6602.
23. Huang WC, Chen JJ, Chen CC. 2003. c-Src-dependent tyrosine phosphorylation of IKKβ is involved in tumor necrosis factor-α- induced intercellular adhesion molecule-1 expression. J Biol Chem 278:9944-9952.
24. Javaid K, Rahman A, Anwar KN, Frey RS, Minshall RD, Malik AB. 2003. Tumor necrosis factor-α induces early-onset endothelial adhesivity by protein kinase Cζ-dependent activation of intercellular adhesion molecule-1. Circ Res 92:1089-1097.
25. Kim I, Moon SO, Hoon Kim S, Jin Kim H, Soon Koh Y, Young Koh G. 2001. Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-κB activation in endothelial cells. J Biol Chem 276:7614-7620.
26. Krymskaya VP, Goncharova EA, Ammit AJ, Lim PN, Goncharov DA, Eszterhas A, Panettieri J. 2004. Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration. FASEB J 19:428-430.
27. Kwak YG, Song CH, Yi HK, Hwang PH, Kim JS, Lee KS, Lee YC. 2003. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J Clin Invest 111:1083-1092.
28. Lazaar AL, Panettieri RA, Jr. 2005. Airway smooth muscle: A modulator of airway remodeling in asthma. J Allergy Clin Immunol 116:488-495.
29. Lee CW, Lin WN, Lin CC, Luo SF, Wang JS, Pouyssegur J, Yang CM. 2006. Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-α in human tracheal smooth muscle cells: Involvement of MAPKs, NF-κB, p300, and histone acetylation. J Cell Physiol 207:174-186.
30. Lin FS, Lin CC, Chien CS, Luo SF, Yang CM. 2005. Involvement of p42/p44 MAPK, JNK, and NF-κB in IL-1β-induced ICAM-1 expression in human A549 cells. J Cell Physiol 202:464-473.
31. Ma Z, Shah RC, Chang MJ, Benveniste EN. 2004. Coordination of cell signaling, chromatin remodeling, histone modifications, and regulator recruitment in human matrix metalloproteinase 9 gene transcription. Mol Cell Biol 24:5496-5509.
32. Min JK, Kim YM, Kim SW, Kwon MC, Kong YY, Hwang IK, Won MH, Rho J, Kwon YG. 2005. TNF-related activation-induced cytokine enhances leukocyte adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF receptor-associated factor and protein kinase C-dependent NF-κB activation in endothelial cells. J Immunol 175:531-540.
33. Nie M, Pang L, Inoue H, Knox AJ. 2003. Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1β in human airway smooth muscle cells: Involvement of different promoter elements, transcription factors, and histone H4 acetylation. Mol Cell Biol 23:9233-9244.
34. Poizat C, Puri PL, Bai Y, Kedes L. 2005. Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells. Mol Cell Biol 25:2673-2687.
35. Qi JH, Ito N, Claesson-Welsh L. 1999. Tyrosine phosphatase SHP-2 is involved in regulation of platelet-derived growth factor-induced migration. J Biol Chem 274:14455-14463.
36. Roth SY, Denu JM, Allis CD. 2001. Histone acetyltransferases. Annu Rev Biochem 70:81-120.
37. Schlessinger J. 2000. New roles for Src kinases in control of cell survival and angiogenesis. Cell 100:293-296.
38. Slomiany BL, Slomiany A. 2004. Src-kinase-dependent epidermal growth factor receptor transactivation in salivary mucin secretion in response to β-adrenergic G-protein-coupled receptor activation. Inflammopharmacology 12:233-245.
39. Szulakowski P, Crowther AJL, Jimenez LA, Donaldson K, Mayer R, Leonard TB, MacNee W, Drost EM. 2006. The effect of smoking on the transcriptional regulation of lung inflammation in COPD patients. Am J Respir Crit Care Med 174:41-50.
40. Takada Y, Fang X, Jamaluddin M, Boyd DD, Aggarwal BB. 2004. Genetic deletion of glycogen synthase kinase-3β abrogates activation of IκBα kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. J Biol Chem 279:39541-39554.
41. Tanimoto T, Lungu AO, Berk BC. 2004. Sphingosine I-phosphate transactivates the platelet-derived growth factor β Receptor and epidermal growth factor receptor in vascular smooth muscle cells. Circ Res 94:1050-1058.
42. Voraberger G, Schafer R, Stratowa C. 1991. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Induction by cytokines and phorbol ester. J Immunol 147:2777-2786.
43. Walzog B, Gaehtgens P. 2000. Adhesion molecules: The path to a new understanding of acute inflammation. News Physiol Sci 15:107-113.
44. Wang CC, Lin WN, Lee CW, Lin CC, Luo SF, Wang JS, Yang CM. 2005. Involvement of p42/p44 MAPK, p38 MAPK, JNK, and NF-κB in IL-1β-induced VCAM-1 expression in human tracheal smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 288:L227-L237.
45. Yang CM, Hsieh HL, Lee CW. 2005. Intracellular signaling mechanisms underlying the expression of pro-inflammatory mediators in airway diseases. Chang Gung Med J 28:813-823.