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Volumn 52, Issue 4, 2006, Pages 3-7

Selectivity among dipeptidyl peptidases of the S9b family

Author keywords

Dipeptidyl peptidase; Neuropeptide Y; Peptide YY; S9b family; Type 2 diabetes

Indexed keywords

DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE 8; DIPEPTIDYL PEPTIDASE 9; DIPEPTIDYL PEPTIDASE IV; NEUROPEPTIDE Y; PEPTIDE YY; UNCLASSIFIED DRUG;

EID: 34247588747     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.1170/T720     Document Type: Conference Paper
Times cited : (8)

References (28)
  • 1
    • 1642534610 scopus 로고    scopus 로고
    • Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation
    • Aertgeerts K., Ye S., Tennant M.G., Kraus M.L., Rogers J., Sang B.C., Skene R.J., Webb D.R. and Prasad G.S., Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation. Protein Sci. 2004, 13: 412-421.
    • (2004) Protein Sci , vol.13 , pp. 412-421
    • Aertgeerts, K.1    Ye, S.2    Tennant, M.G.3    Kraus, M.L.4    Rogers, J.5    Sang, B.C.6    Skene, R.J.7    Webb, D.R.8    Prasad, G.S.9
  • 2
    • 9444285818 scopus 로고    scopus 로고
    • Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
    • Ahren B., Gomis R., Standl E., Mills D. and Schweizer A., Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care. 2004, 27: 2874-2880.
    • (2004) Diabetes Care , vol.27 , pp. 2874-2880
    • Ahren, B.1    Gomis, R.2    Standl, E.3    Mills, D.4    Schweizer, A.5
  • 3
    • 2442482515 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes
    • Ahren B., Landin-Olsson M., Jansson P.A., Svensson M., Holmes D. and Schweizer A., Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes. J. Clin. Endocrinol. Metab. 2004 89: 2078-2084.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 2078-2084
    • Ahren, B.1    Landin-Olsson, M.2    Jansson, P.A.3    Svensson, M.4    Holmes, D.5    Schweizer, A.6
  • 5
    • 3042734543 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity
    • Ajami, K., Abbott, C.A., McCaughan, G.W. and Gorrell, M.D., Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity. Biochim. Biophys. Acta. 2004, 1679: 18-28.
    • (2004) Biochim. Biophys. Acta , vol.1679 , pp. 18-28
    • Ajami, K.1    Abbott, C.A.2    McCaughan, G.W.3    Gorrell, M.D.4
  • 8
    • 0037102412 scopus 로고    scopus 로고
    • Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
    • Cheng J.D., Dunbrack R.L. Jr., Valianou M., Rogatko A., Alpaugh R.K. and Weiner L.M., Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res. 2002, 62: 4767-4772.
    • (2002) Cancer Res , vol.62 , pp. 4767-4772
    • Cheng, J.D.1    Dunbrack Jr., R.L.2    Valianou, M.3    Rogatko, A.4    Alpaugh, R.K.5    Weiner, L.M.6
  • 10
    • 17144404555 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
    • Gorrell M.D., Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders. Clin Sci (Lond). 2005, 108: 277-292.
    • (2005) Clin Sci (Lond) , vol.108 , pp. 277-292
    • Gorrell, M.D.1
  • 11
    • 0031690479 scopus 로고    scopus 로고
    • Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes
    • Holst J.J. and Deacon C.F., Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes. Diabetes. 1998, 47: 1663-1670.
    • (1998) Diabetes , vol.47 , pp. 1663-1670
    • Holst, J.J.1    Deacon, C.F.2
  • 12
    • 0013986243 scopus 로고
    • A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-betanaphthylamide
    • Hopsu-Havu, V.K. and Glenner, G.G., A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-betanaphthylamide. Histochemie. 1966, 7: 197-201.
    • (1966) Histochemie , vol.7 , pp. 197-201
    • Hopsu-Havu, V.K.1    Glenner, G.G.2
  • 15
    • 19944427998 scopus 로고    scopus 로고
    • Kim D., Wang L., Beconi M., Eiermann G.J., Fisher M.H., He H., Hickey G.J., Kowalchick J.E., Leiting B., Lyons K., Marsilio F., McCann M.E., Patel R.A., Petrov A., Scapin G., Patel S.B., Roy R.S., Wu J.K., Wyvratt M.J., Zhang B.B., Zhu L., Thornberry N.A. and Weber A.E., (2R)-4-oxo-4-[3-(trifluoromethyl)- 5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl) butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J. Med. Chem. 2005, 48: 141-151.
    • Kim D., Wang L., Beconi M., Eiermann G.J., Fisher M.H., He H., Hickey G.J., Kowalchick J.E., Leiting B., Lyons K., Marsilio F., McCann M.E., Patel R.A., Petrov A., Scapin G., Patel S.B., Roy R.S., Wu J.K., Wyvratt M.J., Zhang B.B., Zhu L., Thornberry N.A. and Weber A.E., (2R)-4-oxo-4-[3-(trifluoromethyl)- 5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl) butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J. Med. Chem. 2005, 48: 141-151.
  • 16
    • 0029118049 scopus 로고
    • Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
    • Kieffer T.J., McIntosh C.H. and Pederson R.A., Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology. 1995, 136: 3585-3596.
    • (1995) Endocrinology , vol.136 , pp. 3585-3596
    • Kieffer, T.J.1    McIntosh, C.H.2    Pederson, R.A.3
  • 17
    • 0035798196 scopus 로고    scopus 로고
    • Lambeir A.M., Durinx C., Proost P., Van Damme J., Scharpe S. and De Meester I., Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion. FEBS Lett. 2001, 507: 327-330. Erratum in: FEBS Lett. 2002, 512(1-3): 353.
    • Lambeir A.M., Durinx C., Proost P., Van Damme J., Scharpe S. and De Meester I., Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion. FEBS Lett. 2001, 507: 327-330. Erratum in: FEBS Lett. 2002, 512(1-3): 353.
  • 22
    • 0027215348 scopus 로고
    • Dipeptidylpeptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
    • Mentlein R., Gallwitz B. and Schmidt W.E., Dipeptidylpeptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum., Eur. J. Biochem. 1993, 15: 829-835.
    • (1993) Eur. J. Biochem , vol.15 , pp. 829-835
    • Mentlein, R.1    Gallwitz, B.2    Schmidt, W.E.3
  • 23
    • 0033579444 scopus 로고    scopus 로고
    • Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
    • Park J.E., Lenter M.C., Zimmermann R.N., Garin-Chesa P., Old L.J., Rettig W.J., Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J. Biol. Chem. 1999, 274: 36505-36512.
    • (1999) J. Biol. Chem , vol.274 , pp. 36505-36512
    • Park, J.E.1    Lenter, M.C.2    Zimmermann, R.N.3    Garin-Chesa, P.4    Old, L.J.5    Rettig, W.J.6
  • 24
    • 0020360698 scopus 로고
    • Isolation and characterization of dipeptidyl peptidase IV from human placenta
    • Puschel, G., Mentlein, R. and Heymann, E., Isolation and characterization of dipeptidyl peptidase IV from human placenta. Eur. J. Biochem. 1982, 126: 359-365.
    • (1982) Eur. J. Biochem , vol.126 , pp. 359-365
    • Puschel, G.1    Mentlein, R.2    Heymann, E.3
  • 25
    • 0037219684 scopus 로고    scopus 로고
    • Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog
    • Rasmussen H.B., Branner S., Wiberg F.C. and Wagtmann N., Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog. Nat. Struct. Biol. 2003, 10:19-25.
    • (2003) Nat. Struct. Biol , vol.10 , pp. 19-25
    • Rasmussen, H.B.1    Branner, S.2    Wiberg, F.C.3    Wagtmann, N.4
  • 28
    • 30444442517 scopus 로고    scopus 로고
    • Tsu H., Chen X., Chen C.T., Lee S.J., Chang C.N., Kao K.H., Coumar M.S., Yeh Y.T., Chien C.H., Wang H.S., Lin K.T., Chang Y.Y., Wu S.H., Chen Y.S., Lu I.L., Wu S.Y., Tsai T.Y., Chen W.C., Hsieh H.P., Chao Y.S. and Jiaang W.T., 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptidederived inhibitor of dipeptidyl peptidase IV. J. Med. Chem. 2006, 49: 373-380.
    • Tsu H., Chen X., Chen C.T., Lee S.J., Chang C.N., Kao K.H., Coumar M.S., Yeh Y.T., Chien C.H., Wang H.S., Lin K.T., Chang Y.Y., Wu S.H., Chen Y.S., Lu I.L., Wu S.Y., Tsai T.Y., Chen W.C., Hsieh H.P., Chao Y.S. and Jiaang W.T., 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptidederived inhibitor of dipeptidyl peptidase IV. J. Med. Chem. 2006, 49: 373-380.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.