l-Stepholidine increases the frequency of sEPSC via the activation of D1 dopamine signaling pathway in rat prelimbic cortical neurons

Acta Pharmacologica Sinica

Volumn 28, Issue 5, 2007, Pages 627-633

  Gao, Ming ^a   Liu, Chang Liang ^a   Yang, Shen ^a   Zhen, Xue Chu ^a   Jin, Guo Zhang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Dopamine receptor; l stepholidine; Prelimbic cortex; Spontaneous excitatory postsynaptic currents; Whole cell patch clamp

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CHELERYTHRINE; DOPAMINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; STEPHOLIDINE; SULPIRIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN NERVE CELL; BRAIN TISSUE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG ACTIVITY; DRUG MECHANISM; EXCITATORY POSTSYNAPTIC POTENTIAL; LIMBIC SYSTEM; NEUROPHARMACOLOGY; NONHUMAN; PATCH CLAMP; PHARMACODYNAMICS; PYRAMIDAL NERVE CELL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BERBERINE; CEREBRAL CORTEX; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; HUMANS; NEURONS; PATCH-CLAMP TECHNIQUES; PRESYNAPTIC TERMINALS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; SIGNAL TRANSDUCTION;

EID: 34247585646     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2007.00547.x     Document Type: Article

References (50)

1. Dong ZJ, Chen LJ, Jin GZ, Creese I. Gtp regulation of (-)-stepholidine binding to R(h) of D1 dopamine receptors in calf striatum. Biochem Pharmacol 1997 54 : 227 32.
2. Jin GZ, Zhu ZT, Fu Y. (-)-stepholidine: A potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions. Trends Pharmacol Sci 2002 23 : 4 7.
3. Shi WX, Chen Y, Jin GZ. Effect of l-stepholidine on rotational behavior in rats. Acta Pharmacol Sin 1984 5 : 222 5.
4. Xu SX, Yu LP, Han YR, Chen Y, Jin GZ. Effects of tetrahydro- protoberberines on dopamine receptor subtypes in brain. Acta Pharmacol Sin 1989 10 : 104 10.
5. Zou LL, Liu J, Jin GZ. Involvement of receptor reserve in D1 agonistic action of (-)-stepholidine in lesioned rats. Biochem Pharmacol 1997 54 : 233 40.
6. Dong ZJ, Guo X, Chen LJ, Han YF, Jin GZ. Dual actions of (-)-stepholidine on the dopamine receptor-mediated adenylate cyclase activity in rat corpus striatum. Life Sci 1997 61 : 465 72.
7. Wu DC, Xing XZ, Wang WA, Xie H, Wang YH, Wang XY, et al. A double-blind comparison trial of l-stepholidine and perphenazine in treatmeat of schizophrenia. Chin J New Drugs Clin Remedies 2003 22 : 155 9.
8. Cai N. A controlled study on the treatment of tardive dyskinesia using l-stepholidine. Zhonghua Shen Jing Jing Shen Ke Za Zhi 1988 21 : 281 3.
9. Goldman-Rakic PS. The cortical dopamine system: Role in memory and cognition. Adv Pharmacol 1998 42 : 707 11.
10. Goldman-Rakic PS, Castner SA, Svensson TH, Siever LJ, Williams GV. Targeting the dopamine D1 receptor in schizophrenia: Insights for cognitive dysfunction. Psychopharmacology (Berl) 2004 174 : 3 16.
11. Seamans JK, Yang CR. The principal features and mechanisms of dopamine modulation in the prefrontal cortex. Prog Neurobiol 2004 74 : 1 58.
12. Yang CR, Chen L. Targeting prefrontal cortical dopamine D1 and n-methyl-d-aspartate receptor interactions in schizophrenia treatment. Neuroscientist 2005 11 : 452 70.
13. Brozoski TJ, Brown RM, Rosvold HE, Goldman PS. Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 1979 205 : 929 32.
14. Jentsch JD, Roth RH, Taylor JR. Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: Implications for mental disorders and psychotropic drug action. Prog Brain Res 2000 126 : 433 53.
15. Lindstrom LH, Gefvert O, Hagberg G, Lundberg T, Bergstrom M, Langstrom B, et al. Increased dopamine synthesis rate in medial prefrontal cortex and striatum in schizophrenia indicated by l-(beta-11c) dopa and pet. Biol Psychiatry 1999 46 : 681 8.
16. Murphy BL, Arnsten AF, Goldman-Rakic PS, Roth RH. Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proc Natl Acad Sci USA 1996 93 : 1325 9.
17. Tzschentke TM. Pharmacology and behavioral pharmacology of the mesocortical dopamine system. Prog Neurobiol 2001 63 : 241 320.
18. Winn P. Schizophrenia research moves to the prefrontal cortex. Trends Neurosci 1994 17 : 265 8.
19. Abi-Dargham A, Laruelle M. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: Insights from brain imaging studies. Eur Psychiatry 2005 20 : 15 27.
20. Goldman-Rakic PS, Lidow MS, Gallager DW. Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primate prefrontal cortex. J Neurosci 1990 10 : 2125 38.
21. Goldman-Rakic PS, Muly EC 3rd., Williams GV. D1 receptors in prefrontal cells and circuits. Brain Res Rev 2000 31 : 295 301.
22. Sawaguchi T, Goldman-Rakic PS. D1 dopamine receptors in prefrontal cortex: Involvement in working memory. Science 1991 251 : 947 50.
23. Davis KL, Kahn RS, Ko G, Davidson M. Dopamine in schizophrenia: A review and reconceptualization. Am J Psychiatry 1991 148 : 1474 86.
24. Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987 44 : 660 9.
25. Berger B, Thierry AM, Tassin JP, Moyne MA. Dopaminergic innervation of the rat prefrontal cortex: A fluorescence histochemical study. Brain Res 1976 106 : 133 45.
26. Conde F, Audinat E, Maire-Lepoivre E, Crepel F. Afferent connections of the medial frontal cortex of the rat. A study using retrograde transport of fluorescent dyes. I. Thalamic afferents. Brain Res Bull 1990 24 : 341 54.
27. Herkenham M. Laminar organization of thalamic projections to the rat neocortex. Science 1980 207 : 532 5.
28. Penit-Soria J, Audinat E, Crepel F. Excitation of rat prefrontal cortical neurons by dopamine: An in vitro electrophysiological study. Brain Res 1987 425 : 263 74.
29. Ray JP, Price JL. The organization of the thalamocortical connections of the mediodorsal thalamic nucleus in the rat, related to the ventral forebrain-prefrontal cortex topography. J Comp Neurol 1992 323 : 167 97.
30. Carr DB, Sesack SR. Hippocampal afferents to the rat prefrontal cortex: Synaptic targets and relation to dopamine terminals. J Comp Neurol 1996 369 : 1 15.
31. Goldman-Rakic PS, Leranth C, Williams SM, Mons N, Geffard M. Dopamine synaptic complex with pyramidal neurons in primate cerebral cortex. Proc Natl Acad Sci USA 1989 86 : 9015 19.
32. Smiley JF, Goldman-Rakic PS. Heterogeneous targets of dopamine synapses in monkey prefrontal cortex demonstrated by serial section electron microscopy: A laminar analysis using the silver-enhanced diaminobenzidine sulfide (SEDS) immunolabeling technique. Cereb Cortex 1993 3 : 223 38.
33. Wang Z, Feng XQ, Zheng P. Activation of presynaptic D1 dopamine receptors by dopamine increases the frequency of spontaneous excitatory postsynaptic currents through protein kinase A and protein kinase C in pyramidal cells of rat prelimbic cortex. Neuroscience 2002 112 : 499 508.
34. Liu J, Guo X, Wang BC, Jin GZ. Increased phosphorylation of DARPP-32 by D1 agonistic action of l-stepholidine in the 6-OHDA-lesioned rat striatum. Acta Physiol Sin 1999 51 : 65 72.
35. Sun BC, Zhang XX, Jin GZ. (-)-Stepholidine acts as a D1 partial agonist on firing activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine-lesioned rats. Life Sci 1996 59 : 299 306.
36. Zhang XX, Liu J, Fu Y, Hu GY, Jin GZ. Action sites of rotation and unit firing induced by l-stepholidine and DA agonists in basal ganglia of 6-OHDA-lesioned rats. Acta Pharmacol Sin 1999 20 : 979 86.
37. Zhu ZT, Fu Y, Hu GY, Jin GZ. Electrophysiological study on biphasic firing activity elicited by D1 agonistic-D2 antagonistic action of (-)-stepholidine in nucleus accumbens. Acta Physiol Sin 2000 52 : 123 30.
38. Zhu ZT, Fu Y, Hu GY, Jin GZ. Modulation of medical prefrontal cortical D1 receptors on the excitatory firing activity of nucleus accumbens neurons elicited by (-)-stepholidine. Life Sci 2000 67 : 1265 74.
39. Zhu ZT, Wu WR, Fu Y, Jin GZ. l-stepholidine facilitates inhibition of mPFC DA receptors on subcortical NAc DA release. Acta Pharmacol Sin 2000 21 : 663 7.
40. He Y, Yu LP, Jin GZ. Altered rotation behavior of sensitized rats to effect of l-stepholidine: Implication of dopamine D3R antagonist. Pharmacol Biochem Behav 2007 : in press.
41. Feng XQ, Dong Y, Fu YM, Zhu YH, Sun JL, Zheng P, et al. Progesterone inhibition of dopamine-induced increase in frequency of spontaneous excitatory postsynaptic currents in rat prelimbic cortical neurons. Neuropharmacology 2004 46 : 211 22.
42. Parfitt KD, Madison DV. Phorbol esters enhance synaptic transmission by a presynaptic, calcium-dependent mechanism in rat hippocampus. J Physiol 1993 471 : 245 68.
43. Wang Z, Zheng P. Characterization of spontaneous excitatory synaptic currents in pyramidal cells of rat prelimbic cortex. Brain Res 2001 901 : 303 13.
44. Bouron A, Reuter H. The D1 dopamine receptor agonist SKF-38393 stimulates the release of glutamate in the hippocampus. Neuroscience 1999 94 : 1063 70.
45. Hu XT, White FJ. Dopamine enhances glutamate-induced excitation of rat striatal neurons by cooperative activation of D1 and D2 class receptors. Neurosci Lett 1997 224 : 61 5.
46. Kebabian JW, Petzold GL, Greengard P. Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "Dopamine receptor". Proc Natl Acad Sci USA 1972 69 : 2145 9.
47. Hussain T, Lokhandwala MF. Renal dopamine receptor function in hypertension. Hypertension 1998 32 : 187 97.
48. Kretschmer BD. Modulation of the mesolimbic dopamine system by glutamate: Role of nmda receptors. J Neurochem 1999 73 : 839 48.
49. Olney JW, Newcomer JW, Farber NB. NMDA receptor hypo-function model of schizophrenia. J Psychiatr Res 1999 33 : 523 33.
50. Svensson TH. Dysfunctional brain dopamine systems induced by psychotomimetic NMDA-receptor antagonists and the effects of antipsychotic drugs. Brain Res Rev 2000 31 : 320 9.