Synthesis, structure, and structure-activity relationship analysis of enamines as potential antibacterials

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 12, 2007, Pages 4212-4219

  Xiao, Zhu Ping ^a,b   Xue, Jia Yu ^a   Tan, Shu Hua ^a   Li, Huan Qiu ^a   Zhu, Hai Liang ^a  

^a NANJING UNIVERSITY   (China)

^b SHANGRAO NORMAL UNIVERSITY   (China)

Author keywords

Antibacterial; Crystal structure; Enamine; Structure activity relationship

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTIINFECTIVE AGENT; ENAMINE; ETHYL 3 (2 CHLOROPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; ETHYL 3 (3,2 CHLOROPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; ETHYL 3 (3,5 DIBROMO 4 METHOXYPHENYLAMINO) 2 (4 METHOXYPHENYL)ACRYLATE; ETHYL 3 (3,5 DICHLOROPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; ETHYL 3 (3,5 DICHLOROPHENYLAMINO) 2 (4 METHOXYPHENYL)ACRYLATE; ETHYL 3 (3,5 DIFLUOROPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; ETHYL 3 (3,5 DIFLUOROPHENYLAMINO) 2 (4 METHOXYPHENYL)ACRYLATE; ETHYL 3 (3,5 DIMETHOXYPHENYLAMINO) 2 (4 METHOXYPHENYL)ACRYLATE; ETHYL 3 (4 BROMOPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; ETHYL 3 (4 BROMOPHENYLAMINO) 2 (4 METHOXYPHENYL)ACRYLATE; ETHYL 3 (4 CHLOROPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; ETHYL 3 (4 HYDROXYPHENYLAMINO) 2 (4 METHOXYPHENYL)ACRYLATE; ETHYL 3 (4 HYDROXYPHENYLAMINO) 2 (4 METHYLOXYPHENYL)ACRYLATE; ETHYL 3 (4 METHYLPHENYLAMINO) 2 (4 CHLOROPHENYL)ACRYLATE; KANAMYCIN; PENICILLIN G; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON; ELECTROSPRAY MASS SPECTROMETRY; ISOMER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS FLUORESCENS; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TRICHOPHYTON RUBRUM; X RAY DIFFRACTION;

AMINES; ANTI-BACTERIAL AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; ESCHERICHIA COLI; PSEUDOMONAS FLUORESCENS; STAPHYLOCOCCUS AUREUS; TRICHOPHYTON RUBRUM;

EID: 34247577179     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.060     Document Type: Article

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