Effect of isolated isoflavone supplementation on ABCA1-dependent cholesterol efflux potential in postmenopausal women

Menopause

Volumn 14, Issue 2, 2007, Pages 293-299

  Badeau, Robert ^a,b   Jauhiainen, Matti ^b   Metso, Jari ^b   Nikander, Eini ^c   Tikkanen, Matti J ^a   Ylikorkala, Olavi ^a   Mikkola, Tomi S ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c JORVI HOSPITAL   (Finland)

Author keywords

Equol; Lipids; Lipoproteins; Phytoestrogens; Pre high density lipoprotein

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; ISOFLAVONE; LIPID;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CHOLESTEROL TRANSPORT; FEMALE; HUMAN; INCUBATION TIME; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MACROPHAGE; POSTMENOPAUSE; SUPPLEMENTATION; UPREGULATION;

ADULT; AGED; ANIMALS; APOLIPOPROTEINS; ATP-BINDING CASSETTE TRANSPORTERS; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; FEMALE; HUMANS; HYPERLIPIDEMIAS; ISOFLAVONES; LIPOPROTEINS, HDL; MACROPHAGES; MICE; MIDDLE AGED; PHYTOTHERAPY; POSTMENOPAUSE; SOYBEANS; TREATMENT OUTCOME; TRIGLYCERIDES;

EID: 34247576795     PISSN: 10723714     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.gme.0000236935.51325.4d     Document Type: Article

References (39)

1. Tikkanen MJ, Adlercreutz H. Dietary soy-derived isoflavone phytoestrogens. Could they have a role in coronary heart disease prevention? Biochem Pharmacol 2000;60:1-5.
2. Barnes S. Soy isoflavones - phytoestrogens and what else? J Nutr 2004;134:1225S-1228S.
3. Adlercreutz H, Mazur W. Phyto-oestrogens and Western diseases. Ann Med 1997;29:95-120.
4. US Food and Drug Administration. Soy protein and coronary heart disease. Fed Regist 1999;106:57700-57733.
5. Nikander E, Tiitinen A, Laitinen K, Tikkanen MJ, Ylikorkala O. Effects of isolated isoflavonoids on lipids, lipoproteins, insulin sensitivity, and ghrelin in postmenopausal women. J Clin Endocrinol Metab 2004;89:3567-3572.
6. van der Schouw YT, Kreijkamp-Kaspers S, Peeters PHM, Keinan-Boker L, Rimm EB, Grobbee DE. Prospective study on usual dietary phytoestrogen intake and cardiovascular disease risk in Western women. Circulation 2005;111:465-471.
7. Sacks FM. Dietary phytoestrogens to prevent cardiovascular disease - early promise unfulfilled. Circulation 2005;111:385-387.
8. Setchell KD, Brown NM, Lydeking-Olsen E. The clinical importance of the metabolite equol - a clue to the effectiveness of soy and its isoflavones. J Nutr 2002;132:3577-3584.
9. Fielding C, Fielding P. Molecular physiology of reverse cholesterol transport. J Lipid Res 1995;36:211-228.
10. von Eckardstein A, Nofer JR, Assmann G. High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Arterioscler Thromb Vasc Biol 2001;21:13-27.
11. Mikkola TS, Anthony MS, Clarkson TB, St. Clair RW. Serum cholesterol efflux potential is an independent predictor of coronary artery atherosclerosis. Atherosclerosis 2003;170:31-38.
12. Pajunen P, Syvänne M, Castro G, Nieminen MS, Taskinen MR. Cholesterol efflux capacity in vitro predicts the severity and extent of coronary artery disease in patients with and without type 2 diabetes. Scand Cardiovasc J 2001;35:96-100.
13. Soumian S, Albrecht C, Davies A, Gibbs R. ABCA1 and atherosclerosis. Vasc Med 2005;10:109-119.
14. Wang N, Lan D, Chen W, Matsuura F, Tall AR. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc Natl Acad Sci U S A 2004;101:9774-9779.
15. Oram JF, Lawn RM. ABCA1: the gatekeeper for eliminating excess tissue cholesterol. J Lipid Res 2001;42:1173-1179.
16. Francone OL, Royer L, Boucher G, et al. Increased cholesterol deposition, expression of scavenger receptors, and response to chemotactic factors in ABCA1-deficient macrophages. Arterioscler Thromb Vasc Biol 2005;25:1198-1205.
17. Lawn RM, Wade DP, Couse TL, Wilcox JN. Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues. Arterioscler Thromb Vasc Biol 2001;21:378-385.
18. Vainio S, Ikonen E. Macrophage cholesterol transport: a critical player in foam cell formation. Ann Med 2003;35:146-155.
19. Lewis GF, Radar DJ. New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ Res 2005;96:1221-1232.
20. Nikander E, Kilkkinen A, Metsä-Heikkilä M, et al. A randomized placebo-controlled crossover trial with phytoestrogens in treatment of menopause in breast cancer patients. Obstet Gynecol 2003;101:1213-1220.
21. Tormälä RM, Nikander E, Tiitinen A, Väisänen-Tommiska M, Ylikorkala O, Mikkola TS. Serum cholesterol efflux potential in postmenopausal women treated with isolated isoflavones. Menopause 2006;13:96-101.
22. Yancey PG, Asztalos BF, Stettler N, et al. SR-BI-and ABCA1-mediated cholesterol efflux to serum from patients with Alagille syndrome. J Lipid Res 2004;45:1724-1732.
23. Bortnick AE, Rothblat GH, Stoudt G, et al. The correlation of ATP-binding cassette 1 mRNA levels with cholesterol efflux from various cell lines. J Biol Chem 2000;275:28634-28640.
24. van Haperen R, van Tol A, Vermeulen P, et al. Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice. Arterioscler Thromb Vasc Biol 2000;20:1082-1088.
25. Jaari S, van Dijk K, Olkkonen V, et al. Dynamic changes in mouse lipoproteins induced by transiently expressed human phospholipid transfer protein (PLTP): importance of PLTP in preA-HDL generation. Comp Biochem Physiol B Biochem Mol Biol 2001;128:781-792.
26. Fournier N, Francone O, Rothblat G, et al. Enhanced efflux of cholesterol from ABCA1-expressing macrophages to serum from type IV hypertriglyceridemic subjects. Atherosclerosis 2003;171:287-293.
27. Asztalos BF, Schaefer EJ. HDL in atherosclerosis: actor or bystander? Atherosclerosis 2003;4:21-29.
28. Barter PJ, Nicholls S, Rye KA, Anantharamaiah GM, Navab M, Fogelman AM. Antiinflammatory properties of HDL. Circ Res 2004;95:764-772.
29. Nicholls SJ, Dusting GJ, Cutri B, et al. Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits. Circulation 2005;111:1543-1550.
30. Assanasen C, Mineo C, Seetharam D, et al. Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling. J Clin Invest 2005;115:969-977.
31. Kiss RS, Maric J, Marcel YL. Lipid efflux in human and mouse macrophagic cells - evidence for differential regulation of phospholipid and cholesterol efflux. J Lipid Res 2005;46:1877-1887.
32. Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR. J Lipid Res 2003;44:1728-1736.
33. Kreijkamp-Kaspers S, Kok L, Grobbee, et al. Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. JAMA 2004;292:65-74.
34. Kaamanen M, Adlercreutz H, Jauhiainen M, Tikkanen MJ. Accumulation of genistein and lipophilic genistein derivatives in lipoproteins during incubation with human plasma in vitro. Biochim Biophys Acta 2003;1631:147-152.
35. Tikkanen MJ, Wahala K, Ojala S, Vihma V, Adlercreutz H. Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance. Proc Natl Acad Sci U S A 1998;95:3106-3110.
36. Walker HA, Dean TS, Sanders TAB, Jackson G, Ritter JM, Chowienczyk PJ. The phytoestrogen genistein produces acute nitric oxide-dependent dilation of human forearm vasculature with similar potency to 17β-estradiol. Circulation 2001;103:258-262.
37. Honore E, Williams J, Anthony M, Clarkson TB. Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques. Fertil Steril 1997;67:148-154.
38. Wagner JD, Schwenke DC, Greaves KA, et al. Soy protein with isoflavones, but not an isoflavone-rich supplement, improves arterial low-density lipoprotein metabolism and atherogenesis. Arterioscler Thromb Vasc Biol 2003;23:2241-2246.
39. Sirtori C, Arnoldi A, Johnson S. Phytoestrogens - end of a tale? Ann Med 2005;37:423-438.