PEGylation of cholecystokinin prolongs its anorectic effect in rats

Peptides

Volumn 28, Issue 5, 2007, Pages 1003-1011

  León Tamariz, Fabián ^a   Verbaeys, Isabelle ^a   Van Boven, Maurits ^a   De Cuyper, Marcel ^a   Buyse, Johan ^a   Clynen, Elke ^b   Cokelaere, Marnix ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Campus Gasthuisberg   (Belgium)

Author keywords

Appetite suppression; Cholecystokinin; Food intake; PEGylation

Indexed keywords

ARGININE; CHOLECYSTOKININ; MACROGOL; SULFATE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; CONJUGATION; CONTROLLED STUDY; FOOD INTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INCUBATION TIME; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; ANOREXIA; CHOLECYSTOKININ; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DRUG STABILITY; EATING; INJECTIONS, INTRAPERITONEAL; MALE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PEPTIDE FRAGMENTS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

RATTUS;

EID: 34247550350     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.02.009     Document Type: Article

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