Adjuvant Chemotherapy Improves Survival after Resection of Hepatic Colorectal Metastases: Analysis of Data from Two Continents

Journal of the American College of Surgeons

Volumn 204, Issue 5, 2007, Pages 753-761

  Parks, Rowan ^a   Gonen, Mithat ^b   Kemeny, Nancy ^b   Jarnagin, William ^b   D'Angelica, Michael ^b   DeMatteo, Ronald ^b   Garden, O James ^a   Blumgart, Leslie H ^b   Fong, Yuman ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; FLUOROURACIL;

ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; ADULT; AGED; ARTICLE; CANCER CENTER; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; DATA BASE; FEMALE; HUMAN; LIVER METASTASIS; LIVER TUMOR; LOG RANK TEST; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS; OUTCOME ASSESSMENT; PERIOPERATIVE PERIOD; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; SCORING SYSTEM; SURGICAL MORTALITY;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; CHEMOTHERAPY, ADJUVANT; CHI-SQUARE DISTRIBUTION; COLORECTAL NEOPLASMS; EUROPE; FEMALE; FLUOROURACIL; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; TREATMENT OUTCOME; UNITED STATES;

EID: 34247550169     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2006.12.036     Document Type: Article

References (56)

1. Fong Y., Fortner J.G., Sun R., et al. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 230 (1999) 309-321
2. Nordlinger B., Guiguet M., Vaillant J.C., et al. Surgical resection of colorectal carcinoma metastases to the liver. A prognostic scoring system to improve case selection, based on 1568 patients. Association Francaise de Chirurgie Cancer 77 (1996) 1254-1262
3. Adam R., Delvart V., Pascal G., et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann Surg 240 (2004) 644-657
4. Gayowski T.J., Iwatsuki S., Madariaga J.R., et al. Experience in hepatic resection for metastatic colorectal cancer: Analysis of clinical and pathological risk factors. Surgery 116 (1994) 703-711
5. Rosen C.B., Nagorney D.M., Taswell H.F., et al. Perioperative blood transfusion and determinants of survival after liver resection for metastatic colorectal carcinoma. Ann Surg 216 (1992) 492-505
6. Scheele J., Stang R., Altendorf-Hofmann A., et al. Resection of colorectal liver metastases. World J Surg 19 (1995) 59-71
7. Jaffe B.M., Donegan W.L., Watson F., et al. Factors influencing survival in patients with untreated hepatic metastases. Surg Gynecol Obstet 127 (1968) 1-11
8. Chang A.E., Schneider P.D., Sugarbaker P.H., et al. A prospective randomized trial of regional vs systemic continuous 5-FU chemotherapy in the treatment of colorectal metastases. Ann Surg 206 (1987) 685-693
9. Cunningham D., Pyrhonen S., James R.D., et al. Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 352 (1998) 1413-1418
10. Cunningham D., Humblet Y., Siena S., et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351 (2004) 337-345
11. Hurwitz H., Fehrenbacher L., Novotny W., et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350 (2004) 2335-2342
12. Kemeny M.M., Goldberg D., Beatty D., et al. Results of a prospective randomized trial of continuous regional chemotherapy and hepatic resection as treatment of hepatic metastases from colorectal primaries. Cancer 57 (1986) 492-498
13. Lorenz M., Muller H.H., Schramm H., et al. Randomized trial of surgery versus surgery followed by adjuvant hepatic arterial infusion with 5-fluorouracil and folinic acid for liver metastases of colorectal cancer. Ann Surg 228 (1998) 756-762
14. Kemeny M.M., Adak S., Gray B., et al. Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy-an intergroup study. J Clin Oncol 20 (2002) 1499-1505
15. Kemeny N., Huang Y., Cohen A.M., et al. Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer. N Engl J Med 341 (1999) 2039-2048
16. Lygidakis N.J., Sgourakis G., Vlachos L., et al. Metastatic liver disease of colorectal origin: the value of locoregional immunochemotherapy combined with systemic chemotherapy following liver resection. Results of a prospective randomized study. Hepatogastroenterology 48 (2001) 1685-1691
17. O'Connell M.J., Adson M.A., Schutt A.J., et al. Clinical trial of adjuvant chemotherapy after surgical resection of colorectal cancer metastatic to the liver. Mayo Clin Proc 60 (1985) 517-520
18. Portier G., Elias D., Bouche O., et al. Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases: FFCD ACHBTH AURC 9002 trial. J Clin Oncol 24 (2006) 4976-4982
19. Mala T., Bohler G., Mathisen O., et al. Hepatic resection for colorectal metastases: can preoperative scoring predict patient outcome?. World J Surg 26 (2002) 1348-1353
20. Matthews D.E., and Farewell V.T. Understanding medical statistics (1990), Karger, New York
21. Cox D.R. Regression models and life tables. (with discussion). J R Statist Soc B (1972) 187-220
22. Connor S., Hart M.G., Redhead D.N., et al. Followup and outcomes for resection of colorectal liver metastases in Edinburgh. Eur J Surg Oncol (2006) [epub].
23. Maeda T., Hasebe Y., Hanawa S., et al. Trial of percutaneous hepatic cryotherapy: preliminary report. Nippon Geka Gakkai Zasshi - Journal of the Japanese Surgical Society 93 (1992) 666
24. Ekberg H., Tranberg K.G., Andersson R., et al. Pattern of recurrence in liver resection for colorectal secondaries. World J Surg 11 (1987) 541-547
25. Bozzetti F., Bignami P., Morabito A., et al. Patterns of failure following surgical resection of colorectal cancer liver metastases. Ann Surg 205 (1987) 264-270
26. Hohenberger P., Schlag P., Schwarz V., et al. Tumor recurrence and options for further treatment after resection of liver metastases in patients with colorectal cancer. J Surg Oncol 44 (1990) 245-251
27. Nordlinger B., Parc R., Delva E., et al. Hepatic resection for colorectal liver metastases. Ann Surg 205 (1987) 256-263
28. Kemeny N., Daly J., Reichman B., et al. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma. Ann Int Med 107 (1987) 459-465
29. Chang A.E., Schneider P.D., Sugarbaker P.H., et al. A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. Ann Surg 206 (1987) 685-693
30. Hohn D.C., Stagg R.J., Friedman M.A., et al. A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: the Northern California Oncology Group trial. J Clin Oncol 7 (1989) 1646-1654
31. Martin J.K., O'Connell M.J., Wieand H.S., et al. Intra-arterial floxuridine vs systemic fluorouracil for hepatic metastases from colorectal cancer. Arch Surg 125 (1990) 1022-1027
32. Rougier P., Laplanche A., Huguier M., et al. Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long-term results of a prospective randomized trial. J Clin Oncol 10 (1992) 1112-1118
33. Marcove R.C., Searfoss R.C., Whitmore W.F., et al. Cryosurgery in the treatment of bone metastases from renal cell carcinoma. Clin Orthop 127 (1977) 220-227
34. Goodie D.B., Horton M.D., Morris R.W., et al. Anaesthetic experience with cryotherapy for treatment of hepatic malignancy. Anaesth Intens Care 20 (1992) 491-496
35. Moriya Y., Sugihara K., Hojo K., et al. Adjuvant hepatic intra-arterial chemotherapy after potentially curative hepatectomy for liver metastases from colorectal cancer: a pilot study. Eur J Surg Oncol 17 (1991) 519-525
36. Curley S.A., Roh M.S., Chase J.L., et al. Adjuvant hepatic artery infusion chemotherapy after curative resection of colorectal liver metastases. Am J Surg 166 (1993) 743-748
37. Iwasuki S., Esquivel C.O., Gordon R.D., and Starzl T.E. Liver resection for metastatic colorectal cancer. Surgery 100 (1986) 804-810
38. Hughes K.S., Simons R., Songhorabodi S., et al. Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of indications for resection. Surgery 103 (1988) 278-288
39. Banerjee D., Gorlick R., Liefshitz A., et al. Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase. Cancer Res 60 (2000) 2365-2367
40. Gorlick R., Metzger R., Danenberg K.D., et al. Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma. J Clin Oncol 16 (1998) 1465-1469
41. Kemeny N., Jarnagin W., Gonen M., et al. Phase I/II study of hepatic arterial therapy with floxuridine and dexamethasone in combination with intravenous irinotecan as adjuvant treatment after resection of hepatic metastases from colorectal cancer. J Clin Oncol 21 (2003) 3303-3309
42. Saltz L.B., Niedzwiecki D., Hollis D., et al. Irinotecan plus fluorouracil/leucovorin (IFL) versus fluorouracil/leucovorin alone (FL) in stage III colon cancer (intergroup trial CALGB C89803). J Clin Oncol 22 (2004) 246
43. Kemeny N., Huang Y., Cohen A.M., et al. Randomized study of hepatic arterial infusion and systemic chemotherapy versus systemic chemotherapy alone as adjuvant treatment following resection of hepatic metastases from colorectal cancer. Proc Am Soc Clin Oncol 18 (1999) 163A
44. Cady B., and Stone M.D. The role of surgical resection of liver metastases in colorectal carcinoma. Semin Oncol 18 (1991) 399-406
45. Schussler-Fiorenza C.M., Mahvi D.M., Niederhuber J., et al. Clinical risk score correlates with yield of PET scan in patients with colorectal hepatic metastases. J Gastrointest Surg 8 (2004) 150-157
46. Jarnagin W.R., Conlon K., Bodniewicz J., et al. A clinical scoring system predicts the yield of diagnostic laparoscopy in patients with potentially resectable hepatic colorectal metastases. Cancer 91 (2001) 1121-1128
47. Kemeny N., and Fong Y. Treatment of liver metastases. In: Holland J.F., Frei E., Bast R.C., et al. (Eds). Cancer medicine (1997), Williams & Wilkins, Baltimore 1939-1954
48. Gilbert H.A., and Kagan A.R. Metastases: incidence, detection, and evaluation without histologic confirmation. In: Weiss L. (Ed). Fundamental aspects of metastasis (1976), North-Holland Publishing Company, Amsterdam 385-405
49. Foster J.H. Survival after liver resection for secondary tumors. Am J Surg 135 (1978) 389-394
50. Butler J., Attiyeh F.F., and Daly J.M. Hepatic resection for metastases of the colon and rectum. Surg Gynecol Obstet 162 (1986) 109-113
51. Cobourn C.S., Makowka L., Langer B., et al. Examination of patient selection and outcome for hepatic resection for metastatic disease. Surg Gynecol Obstet 165 (1987) 239-246
52. Schlag P., Hohenberger P., and Herfarth C.H. Resection of liver metastases in colorectal cancer-competitive analysis of treatment results in synchronous versus metachronous metastases. Eu J Surg Oncol 16 (1990) 360-365
53. Younes R.N., Rogatko A., and Brennan M.F. The influence of intraoperative hypotension and perioperative blood transfusion on disease-free survival in patients with complete resection of colorectal liver metastases. Ann Surg 214 (1991) 107-113
54. Scheele J., Stangl R., Altendorf-Hofmann A., et al. Indicators of prognosis after hepatic resection for colorectal secondaries. Surgery 110 (1991) 13-29
55. Cady B., Stone M.D., McDermott Jr. W.V., et al. Technical and biological factors in disease-free survival after hepatic resection for colorectal cancer metastases. Arch Surg 127 (1992) 561-569
56. Fong Y., Cohen A.M., Fortner J.G., et al. Liver resection for colorectal metastases. J Clin Oncol 15 (1997) 938-946